| Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ... Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017 | 110 | 2017 |
| HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors V Cento, C Mirabelli, R Salpini, S Dimonte, A Artese, G Costa, F Mercurio, ... PloS one 7 (7), e39652, 2012 | 109 | 2012 |
| Hybrid ligand–alkylating agents targeting telomeric G-quadruplex structures F Doria, M Nadai, M Folini, M Di Antonio, L Germani, C Percivalle, C Sissi, ... Organic & biomolecular chemistry 10 (14), 2798-2806, 2012 | 101 | 2012 |
| Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses A Artese, V Svicher, G Costa, R Salpini, VC Di Maio, M Alkhatib, ... Drug Resistance Updates 53, 100721, 2020 | 96 | 2020 |
| Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches S Alcaro, C Musetti, S Distinto, M Casatti, G Zagotto, A Artese, L Parrotta, ... Journal of medicinal chemistry 56 (3), 843-855, 2013 | 95 | 2013 |
| New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors I Malet, L Gimferrer Arriaga, A Artese, G Costa, L Parrotta, S Alcaro, ... Journal of Antimicrobial Chemotherapy 69 (8), 2118-2122, 2014 | 85 | 2014 |
| Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to … F Ceccherini-Silberstein, V Svicher, T Sing, A Artese, MM Santoro, ... Journal of virology 81 (20), 11507-11519, 2007 | 83 | 2007 |
| Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome D Bagetta, A Maruca, A Lupia, F Mesiti, R Catalano, I Romeo, F Moraca, ... European journal of medicinal chemistry 186, 111903, 2020 | 78 | 2020 |
| The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile A Maruca, R Catalano, D Bagetta, F Mesiti, FA Ambrosio, I Romeo, ... European journal of medicinal chemistry 181, 111579, 2019 | 72 | 2019 |
| Hepatitis C virus genetic variability and the presence of NS5B resistance-associated mutations as natural polymorphisms in selected genotypes could affect the response to NS5B … VC Di Maio, V Cento, C Mirabelli, A Artese, G Costa, S Alcaro, CF Perno, ... Antimicrobial agents and chemotherapy 58 (5), 2781-2797, 2014 | 69 | 2014 |
| Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors F Ceccherini-Silberstein, I Malet, L Fabeni, S Dimonte, V Svicher, ... Journal of antimicrobial chemotherapy 65 (11), 2305-2318, 2010 | 63 | 2010 |
| SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation L D''antona, R Amato, C Talarico, F Ortuso, M Menniti, V Dattilo, R Iuliano, ... Cellular physiology and biochemistry 35 (5), 2006-2018, 2015 | 61 | 2015 |
| Kaempferol as selective human MAO-A inhibitor: analytical detection in calabrian red wines, biological and molecular modeling studies MC Gidaro, C Astorino, A Petzer, S Carradori, F Alcaro, G Costa, A Artese, ... Journal of agricultural and food chemistry 64 (6), 1394-1400, 2016 | 60 | 2016 |
| (3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase R Meleddu, S Distinto, A Corona, G Bianco, V Cannas, F Esposito, ... European journal of medicinal chemistry 93, 452-460, 2015 | 59 | 2015 |
| Molecular interaction fields in drug discovery: recent advances and future perspectives A Artese, S Cross, G Costa, S Distinto, L Parrotta, S Alcaro, F Ortuso, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 3 (6), 594-613, 2013 | 53 | 2013 |
| SARS-CoV-2 variants and their relevant mutational profiles: update summer 2021 M Alkhatib, V Svicher, R Salpini, FA Ambrosio, MC Bellocchi, L Carioti, ... Microbiology spectrum 9 (3), e01096-21, 2021 | 51 | 2021 |
| Update on SARS-CoV-2 omicron variant of concern and its peculiar mutational profile M Alkhatib, R Salpini, L Carioti, FA Ambrosio, S D’Anna, L Duca, G Costa, ... Microbiology spectrum 10 (2), e02732-21, 2022 | 47 | 2022 |
| Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir-containing regimens V Svicher, C Alteri, A Artese, F Forbici, MM Santoro, D Schols, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 55 (3), 336-344, 2010 | 45 | 2010 |
| In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold F Ortuso, R Amato, A Artese, L D’antona, G Costa, C Talarico, F Gigliotti, ... Journal of chemical information and modeling 54 (7), 1828-1832, 2014 | 44 | 2014 |
| Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures C Percivalle, C Sissi, ML Greco, C Musetti, A Mariani, A Artese, G Costa, ... Organic & biomolecular chemistry 12 (22), 3744-3754, 2014 | 44 | 2014 |
