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Matthew J. Smith
Matthew J. Smith
Principal Investigator, IRIC, Université de Montréal
Verified email at umontreal.ca - Homepage
Title
Cited by
Cited by
Year
Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion
N Ishiyama, SH Lee, S Liu, GY Li, MJ Smith, LF Reichardt, M Ikura
Cell 141 (1), 117-128, 2010
3962010
Inhibition of RAS function through targeting an allosteric regulatory site
R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ...
Nature chemical biology 13 (1), 62-68, 2017
2692017
NMR-based functional profiling of RASopathies and oncogenic RAS mutations
MJ Smith, BG Neel, M Ikura
Proceedings of the National Academy of Sciences 110 (12), 4574-4579, 2013
2612013
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site
MT Mazhab-Jafari, CB Marshall, MJ Smith, GMC Gasmi-Seabrook, ...
Proceedings of the National Academy of Sciences 112 (21), 6625-6630, 2015
2052015
Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays
MJ Smith, WR Hardy, JM Murphy, N Jones, T Pawson
Molecular and cellular biology 26 (22), 8461-8474, 2006
1382006
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators
MJ Smith, M Ikura
Nature chemical biology 10 (3), 223-230, 2014
912014
FF domains of CA150 bind transcription and splicing factors through multiple weak interactions
MJ Smith, S Kulkarni, T Pawson
Molecular and cellular biology, 2004
832004
Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase
N Jones, WR Hardy, MB Friese, C Jorgensen, MJ Smith, NM Woody, ...
Molecular and cellular biology 27 (13), 4759-4773, 2007
822007
Real-time NMR monitoring of biological activities in complex physiological environments
MJ Smith, CB Marshall, FX Theillet, A Binolfi, P Selenko, M Ikura
Current opinion in structural biology 32, 39-47, 2015
702015
Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate
GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ...
Cell 152 (5), 1008-1020, 2013
682013
Real-time NMR study of three small GTPases reveals that fluorescent 2′(3′)-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics
MT Mazhab-Jafari, CB Marshall, M Smith, GMC Gasmi-Seabrook, ...
Journal of biological chemistry 285 (8), 5132-5136, 2010
542010
Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts
CB Marshall, D Meiri, MJ Smith, MT Mazhab-Jafari, ...
Methods 57 (4), 473-485, 2012
532012
A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues
D Long, CB Marshall, G Bouvignies, MT Mazhab‐Jafari, MJ Smith, M Ikura, ...
Angewandte Chemie 125 (41), 10971-10974, 2013
492013
Structure of the DOCK2− ELMO1 complex provides insights into regulation of the auto-inhibited state
L Chang, J Yang, CH Jo, A Boland, Z Zhang, SH McLaughlin, ...
Nature communications 11 (1), 3464, 2020
402020
Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel
RC Killoran, MJ Smith
Journal of Biological Chemistry 294 (25), 9937-9948, 2019
362019
The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1
MJ Smith, WR Hardy, GY Li, M Goudreault, S Hersch, P Metalnikov, ...
The EMBO Journal 29 (5), 884-896, 2010
332010
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia
MJ Smith, E Ottoni, N Ishiyama, M Goudreault, A Haman, C Meyer, ...
Nature Communications 8 (1), 1099, 2017
282017
Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival
TK Lundgren, RP Scott, M Smith, T Pawson, P Ernfors
Journal of biological chemistry 281 (40), 29886-29896, 2006
232006
RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway
T Dhanaraman, S Singh, RC Killoran, A Singh, X Xu, JM Shifman, ...
Science Signaling 13 (653), eabb4778, 2020
222020
Biochemical classification of disease-associated mutants of RAS-like protein expressed in many tissues (RIT1)
Z Fang, CB Marshall, JC Yin, MT Mazhab-Jafari, GMC Gasmi-Seabrook, ...
Journal of Biological Chemistry 291 (30), 15641-15652, 2016
202016
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