| Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ... Cell 154 (2), 452-464, 2013 | 520 | 2013 |
| The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues S Al-Mahdawi, RM Pinto, O Ismail, D Varshney, S Lymperi, C Sandi, ... Human molecular genetics 17 (5), 735-746, 2008 | 312 | 2008 |
| Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ... Brain 143 (8), 2576-2593, 2020 | 266 | 2020 |
| Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia GP Crossan, L van Der Weyden, IV Rosado, F Langevin, PHL Gaillard, ... Nature genetics 43 (2), 147-152, 2011 | 240 | 2011 |
| Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease N Colgan, B Siow, JM O'Callaghan, IF Harrison, JA Wells, HE Holmes, ... Neuroimage 125, 739-744, 2016 | 219 | 2016 |
| Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI IF Harrison, B Siow, AB Akilo, PG Evans, O Ismail, Y Ohene, P Nahavandi, ... Elife 7, e34028, 2018 | 144 | 2018 |
| Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study Y Ohene, IF Harrison, P Nahavandi, O Ismail, EV Bird, OP Ottersen, ... Neuroimage 188, 515-523, 2019 | 114 | 2019 |
| The role of sphingosine-1-phosphate transporter Spns2 in immune system function A Nijnik, S Clare, C Hale, J Chen, C Raisen, L Mottram, M Lucas, ... The Journal of Immunology 189 (1), 102-111, 2012 | 102 | 2012 |
| The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation A Nijnik, S Clare, C Hale, C Raisen, RE McIntyre, K Yusa, AR Everitt, ... Blood, The Journal of the American Society of Hematology 119 (6), 1370-1379, 2012 | 102 | 2012 |
| Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome RE McIntyre, P Lakshminarasimhan Chavali, O Ismail, DM Carragher, ... PLoS genetics 8 (11), e1003022, 2012 | 101 | 2012 |
| In vivo imaging of tau pathology using multi-parametric quantitative MRI JA Wells, JM O'Callaghan, HE Holmes, NM Powell, RA Johnson, B Siow, ... Neuroimage 111, 369-378, 2015 | 99 | 2015 |
| Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength JHD Bassett, A Gogakos, JK White, H Evans, RM Jacques, ... Public Library of Science 8 (8), e1002858, 2012 | 91 | 2012 |
| Non-invasive MRI of blood–cerebrospinal fluid barrier function PG Evans, M Sokolska, A Alves, IF Harrison, Y Ohene, P Nahavandi, ... Nature communications 11 (1), 2081, 2020 | 80 | 2020 |
| Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice M Simon, MX Wang, O Ismail, M Braun, AG Schindler, J Reemmer, ... Alzheimer's research & therapy 14 (1), 59, 2022 | 67 | 2022 |
| Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease J O'callaghan, H Holmes, N Powell, JA Wells, O Ismail, IF Harrison, ... Neuroimage 159, 334-345, 2017 | 61 | 2017 |
| Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media J Chen, N Ingham, S Clare, C Raisen, VE Vancollie, O Ismail, RE McIntyre, ... PloS one 8 (3), e58156, 2013 | 46 | 2013 |
| Experimental and husbandry procedures as potential modifiers of the results of phenotyping tests AK Gerdin, N Igosheva, LA Roberson, O Ismail, N Karp, M Sanderson, ... Physiology & behavior 106 (5), 602-611, 2012 | 46 | 2012 |
| Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study STARSurg Collaborative, ... BJS open 2 (6), 400-410, 2018 | 44 | 2018 |
| Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy HE Holmes, NM Powell, D Ma, O Ismail, IF Harrison, JA Wells, N Colgan, ... Frontiers in neuroinformatics 11, 20, 2017 | 44 | 2017 |
| Imaging the accumulation and suppression of tau pathology using multiparametric MRI HE Holmes, N Colgan, O Ismail, D Ma, NM Powell, JM O'Callaghan, ... Neurobiology of aging 39, 184-194, 2016 | 44 | 2016 |
Mark LythgoeProfessor of Biomedical Imaging, University College LondonVerifierad e-postadress på ucl.ac.uk
