MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool H Gad, T Koolmeister, AS Jemth, S Eshtad, SA Jacques, CE Ström, ... Nature 508 (7495), 215-221, 2014 | 531 | 2014 |
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ... Nature 508 (7495), 222-227, 2014 | 435 | 2014 |
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer M Asim, F Tarish, HI Zecchini, K Sanjiv, E Gelali, CE Massie, A Baridi, ... Nature communications 8 (1), 374, 2017 | 249 | 2017 |
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ... Science 362 (6416), 834-839, 2018 | 191 | 2018 |
Cancer-specific synthetic lethality between ATR and CHK1 kinase activities K Sanjiv, A Hagenkort, JM Calderón-Montańo, T Koolmeister, PM Reaper, ... Cell reports 14 (2), 298-309, 2016 | 148 | 2016 |
Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 139 | 2016 |
Targeting DNA repair, DNA metabolism and replication stress as anti‐cancer strategies JC Puigvert, K Sanjiv, T Helleday The FEBS journal 283 (2), 232-245, 2016 | 138 | 2016 |
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies N Herold, SG Rudd, L Ljungblad, K Sanjiv, IH Myrberg, CBJ Paulin, ... Nature medicine 23 (2), 256-263, 2017 | 121 | 2017 |
Development of chitosan oligosaccharide-modified gold nanorods for in vivo targeted delivery and noninvasive imaging by NIR irradiation S Charan, K Sanjiv, N Singh, FC Chien, YF Chen, NN Nergui, SH Huang, ... Bioconjugate chemistry 23 (11), 2173-2182, 2012 | 79 | 2012 |
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites N Herold, SG Rudd, K Sanjiv, J Kutzner, J Bladh, CBJ Paulin, T Helleday, ... Cell Cycle 16 (11), 1029-1038, 2017 | 66 | 2017 |
Global survey of the immunomodulatory potential of common drugs GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ... Nature chemical biology 13 (6), 681-690, 2017 | 60 | 2017 |
Synthesis of tunable and multifunctional Ni-doped near-infrared QDs for cancer cell targeting and cellular sorting N Singh, S Charan, K Sanjiv, SH Huang, YC Hsiao, CW Kuo, FC Chien, ... Bioconjugate chemistry 23 (3), 421-430, 2012 | 58 | 2012 |
The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing M Tanikawa, K Sanjiv, T Helleday, P Herr, O Mortusewicz Oncogenesis 5 (12), e280-e280, 2016 | 53 | 2016 |
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1 N Herold, SG Rudd, K Sanjiv, J Kutzner, IH Myrberg, CBJ Paulin, ... Experimental hematology 52, 32-39, 2017 | 48 | 2017 |
Epidemiological typing of Staphylococcus aureus by DNA restriction fragment length polymorphism of coa gene K Sanjiv, AK Kataria, R Sharma, G Singh Veterinarski arhiv 78 (1), 31-38, 2008 | 47 | 2008 |
Ribonucleotide reductase inhibitors suppress SAMHD 1 ara‐CTP ase activity enhancing cytarabine efficacy SG Rudd, N Tsesmetzis, K Sanjiv, CBJ Paulin, L Sandhow, J Kutzner, ... EMBO molecular medicine 12 (3), e10419, 2020 | 41 | 2020 |
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic acids research 48 (21), 12234-12251, 2020 | 39 | 2020 |
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1 L Pudelko, P Rouhi, K Sanjiv, H Gad, C Kalderén, A Höglund, M Squatrito, ... Oncotarget 8 (49), 84671, 2017 | 35 | 2017 |
Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity PC Lee, HJ Lee, R Kakadiya, K Sanjiv, TL Su, TC Lee Oncogene 32 (9), 1144-1154, 2013 | 32 | 2013 |
The novel DNA alkylating agent BO‐1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models K Sanjiv, TL Su, S Suman, R Kakadiya, TC Lai, HY Wang, M Hsiao, ... International journal of cancer 130 (6), 1440-1450, 2012 | 30 | 2012 |