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Michelle Guignet
Michelle Guignet
Acting Assistant Professor, University of Washington
Verifierad e-postadress på uw.edu - Startsida
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Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status …
EA Johnson, TL Dao, MA Guignet, CE Geddes, AI Koemeter-Cox, RK Kan
Journal of neuroinflammation 8, 1-10, 2011
1342011
Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication
M Guignet, K Dhakal, BM Flannery, BA Hobson, D Zolkowska, A Dhir, ...
Neurobiology of disease 133, 104431, 2020
952020
Development of dendrite polarity in Drosophila neurons
SE Hill, M Parmar, KW Gheres, MA Guignet, Y Huang, FR Jackson, ...
Neural Development 7, 1-13, 2012
572012
Cenobamate (XCOPRI): can preclinical and clinical evidence provide insight into its mechanism of action?
M Guignet, A Campbell, HS White
Epilepsia 61 (11), 2329-2339, 2020
472020
Neuroinflammation in organophosphate-induced neurotoxicity
M Guignet, PJ Lein
Advances in neurotoxicology 3, 35-79, 2019
402019
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate
S Supasai, EA González, DJ Rowland, B Hobson, DA Bruun, MA Guignet, ...
European journal of pharmacology 886, 173538, 2020
272020
The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity
EA González, AC Rindy, MA Guignet, JJ Calsbeek, DA Bruun, A Dhir, ...
Archives of toxicology 94, 2149-2162, 2020
272020
TSPO PET Using [18F]PBR111 Reveals Persistent Neuroinflammation Following Acute Diisopropylfluorophosphate Intoxication in the Rat
BA Hobson, DJ Rowland, S Sisó, MA Guignet, ZT Harmany, SB Bandara, ...
Toxicological Sciences 170 (2), 330-344, 2019
232019
Interleukin-18 expression increases in response to neurovascular damage following soman-induced status epilepticus in rats
EA Johnson, MA Guignet, TL Dao, TA Hamilton, RK Kan
Journal of inflammation 12, 1-11, 2015
232015
Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate‐induced status epilepticus in rats
A Dhir, DA Bruun, M Guignet, YH Tsai, E González, J Calsbeek, J Vu, ...
Annals of the New York Academy of Sciences 1480 (1), 183-206, 2020
222020
Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication
DA Bruun, M Guignet, DJ Harvey, PJ Lein
Neurotoxicology 73, 81-84, 2019
162019
Neuropathological and behavioral sequelae in IL-1R1 and IL-1Ra gene knockout mice after soman (GD) exposure
TM Ferrara-Bowens, JK Chandler, MA Guignet, JF Irwin, K Laitipaya, ...
Neurotoxicology 63, 43-56, 2017
142017
Identification of proteins required for precise positioning of Apc2 in dendrites
AT Weiner, DY Seebold, NL Michael, M Guignet, C Feng, B Follick, ...
G3: Genes, Genomes, Genetics 8 (5), 1841-1853, 2018
102018
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
JJ Calsbeek, EA González, DA Bruun, MA Guignet, N Copping, ...
Neurotoxicology 87, 106-119, 2021
92021
Advances in Neurotoxicology: Role of Inflammation in Environmental Neurotoxicity
M Guignet, PJ Lein, M Aschner, LG Costa
Academic Press, Cambridge, MA 3, 35-79, 2019
92019
Apoptosis as a mechanism of developmental neurotoxicity
PJ Lein, S Supasai, M Guignet
Handbook of Developmental Neurotoxicology, 91-112, 2018
62018
Perampanel’s forgiveness factor in a variable medication adherence paradigm in a rat model of chronic epilepsy
M Guignet, A Campbell, J Vuong, D Whittington, HS White
Journal of Translational Medicine 21 (1), 642, 2023
32023
Developmental toxicity within the central cholinergic nervous system
DA Jett, M Guignet, S Supasai, PJ Lein
Handbook of Developmental Neurotoxicology, 183-198, 2018
22018
Repurposing dimethyl fumarate as an antiepileptogenic and disease-modifying treatment for drug-resistant epilepsy
S Sandouka, PK Singh, A Saadi, RO Taiwo, Y Sheeni, T Zhang, L Deeb, ...
Journal of Translational Medicine 21 (1), 796, 2023
12023
Novel image analysis tool for rapid screening of cell morphology in preclinical animal models of disease
M Guignet, M Schmuck, DJ Harvey, D Nguyen, D Bruun, A Echeverri, ...
Heliyon 9 (2), 2023
12023
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Artiklar 1–20