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Shan Lin
Shan Lin
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Instructive role of MLL-fusion proteins revealed by a model of t (4; 11) pro-B acute lymphoblastic leukemia
S Lin, RT Luo, A Ptasinska, J Kerry, SA Assi, M Wunderlich, T Imamura, ...
Cancer Cell 30 (5), 737-749, 2016
1102016
The AS‐RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation
NT Tran, H Su, A Khodadadi‐Jamayran, S Lin, L Zhang, D Zhou, ...
EMBO reports 17 (6), 887-900, 2016
732016
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO
S Goyama, J Schibler, A Gasilina, M Shrestha, S Lin, KA Link, J Chen, ...
Leukemia 30 (3), 728-739, 2016
622016
The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO
FS Chou, A Griesinger, M Wunderlich, S Lin, KA Link, M Shrestha, ...
Blood 120 (4), 709-719, 2012
592012
RUNX1-ETO Leukemia
S Lin, JC Mulloy, S Goyama
RUNX Proteins in Development and Cancer, 151-173, 2017
582017
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
BKA Seong, NV Dharia, S Lin, KA Donovan, S Chong, A Robichaud, ...
Cancer cell 39 (9), 1262-1278. e7, 2021
542021
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ...
Cancer Cell 39 (6), 827-844. e10, 2021
522021
Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo
Y Tarumoto, S Lin, J Wang, JP Milazzo, Y Xu, B Lu, Z Yang, Y Wei, ...
Blood 135 (1), 56-70, 2020
482020
An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML
S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, M Kuljanin, ...
Cancer Discovery, 2021
432021
A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program
S Lin, A Ptasinska, X Chen, M Shrestha, SA Assi, PS Chin, MR Imperato, ...
Blood 130 (10), 1213-1222, 2017
422017
The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment
S Lin, RT Luo, M Shrestha, MJ Thirman, JC Mulloy
Blood 130 (7), 903-907, 2017
372017
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia
R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ...
Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022
322022
Matched targeted therapy for pediatric patients with relapsed, refractory, or high-risk leukemias: A report from the LEAP consortium
Y Pikman, SK Tasian, ML Sulis, K Stevenson, TM Blonquist, BA Winger, ...
Cancer discovery 11 (6), 1424-1439, 2021
252021
Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation
KA Link, S Lin, M Shrestha, M Bowman, M Wunderlich, CD Bloomfield, ...
Proceedings of the National Academy of Sciences 113 (32), 9075-9080, 2016
232016
Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts
JM Ellegast, G Alexe, A Hamze, S Lin, HJ Uckelmann, PJ Rauch, ...
Cancer Discovery 12 (7), 1760-1781, 2022
182022
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor
N Darabedian, W Ji, M Fan, S Lin, HS Seo, EV Vinogradova, TM Yaron, ...
Nature Chemical Biology, 1-10, 2023
172023
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ...
Nature Cell Biology, 1-13, 2023
152023
Immortalization of human AE pre-leukemia cells by hTERT allows leukemic transformation
S Lin, J Wei, M Wunderlich, FS Chou, JC Mulloy
Oncotarget 7 (35), 55939-55950, 2016
122016
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia
C Larrue, S Mouche, S Lin, F Simonetta, NK Scheidegger, L Poulain, ...
Leukemia 37 (4), 765-775, 2023
82023
The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding
S Lin, A Ptasinska, SA Assi, J Kerry, RA Meetei, RT Luo, MJ Thirman, ...
Blood 128 (22), 576-576, 2016
32016
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