Laura Civiero
Laura Civiero
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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ...
Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014
Glutamate-induced excitotoxicity in Parkinson's disease: The role of glial cells
L Iovino, ME Tremblay, L Civiero
Journal of pharmacological sciences 144 (3), 151-164, 2020
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2
A Biosa, A Trancikova, L Civiero, L Glauser, L Bubacco, E Greggio, ...
Human molecular genetics 22 (6), 1140-1156, 2013
Glial phagocytic clearance in Parkinson’s disease
ME Tremblay, MR Cookson, L Civiero
Molecular neurodegeneration 14 (1), 16, 2019
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
L Civiero, R Vancraenenbroeck, E Belluzzi, A Beilina, E Lobbestael, ...
Public Library of Science 7 (8), e43472, 2012
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate
E Belluzzi, A Gonnelli, MD Cirnaru, A Marte, N Plotegher, I Russo, ...
Molecular neurodegeneration 11, 1-16, 2016
Differential protein–protein interactions of LRRK 1 and LRRK 2 indicate roles in distinct cellular signaling pathways
L Reyniers, MG Del Giudice, L Civiero, E Belluzzi, E Lobbestael, A Beilina, ...
Journal of neurochemistry 131 (2), 239-250, 2014
Analysis of the catecholaminergic phenotype in human SH-SY5Y and BE (2)-M17 neuroblastoma cell lines upon differentiation
R Filograna, L Civiero, V Ferrari, G Codolo, E Greggio, L Bubacco, ...
PLoS one 10 (8), e0136769, 2015
Pharmacological LRRK2 kinase inhibition induces LRRK2 protein destabilization and proteasomal degradation
E Lobbestael, L Civiero, T De Wit, JM Taymans, E Greggio, V Baekelandt
Scientific reports 6 (1), 33897, 2016
RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase–mediated centrosomal cohesion and ciliogenesis deficits
AJ Lara Ordónez, B Fernández, E Fdez, M Romo-Lozano, ...
Human molecular genetics 28 (21), 3552-3568, 2019
Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?
E Greggio, M Bisaglia, L Civiero, L Bubacco
Molecular neurodegeneration 6, 1-10, 2011
BEL β-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms
M Bovi, L Cenci, M Perduca, S Capaldi, ME Carrizo, L Civiero, ...
Glycobiology 23 (5), 578-592, 2013
Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain
L Civiero, MD Cirnaru, A Beilina, U Rodella, I Russo, E Belluzzi, ...
Journal of neurochemistry 135 (6), 1242-1256, 2015
Parkinson’s disease–associated LRRK2 interferes with astrocyte-mediated alpha-synuclein clearance
L Streubel-Gallasch, V Giusti, M Sandre, I Tessari, N Plotegher, E Giusto, ...
Molecular Neurobiology 58, 3119-3140, 2021
LRRK2 deficiency impacts ceramide metabolism in brain
R Ferrazza, S Cogo, H Melrose, L Bubacco, E Greggio, G Guella, ...
Biochemical and biophysical research communications 478 (3), 1141-1146, 2016
PAK6 phosphorylates 14-3-3γ to regulate steady state phosphorylation of LRRK2
L Civiero, S Cogo, A Kiekens, C Morganti, I Tessari, E Lobbestael, ...
Frontiers in molecular neuroscience 10, 417, 2017
Ceramides in Parkinson’s disease: from recent evidence to new hypotheses
N Plotegher, L Bubacco, E Greggio, L Civiero
Frontiers in Neuroscience 13, 446335, 2019
Parkinson’s disease and immune system: is the culprit LRRKing in the periphery?
E Greggio, L Civiero, M Bisaglia, L Bubacco
Journal of Neuroinflammation 9, 1-7, 2012
PAKs in the brain: Function and dysfunction
L Civiero, E Greggio
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (2), 444-453, 2018
The LRRK2 variant E193K prevents mitochondrial fission upon MPP+ treatment by altering LRRK2 binding to DRP1
M Perez Carrion, F Pischedda, A Biosa, I Russo, L Straniero, L Civiero, ...
Frontiers in molecular neuroscience 11, 64, 2018
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