Genetic variation in the 6p22. 3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia RE Straub, Y Jiang, CJ MacLean, Y Ma, BT Webb, MV Myakishev, ... The American Journal of Human Genetics 71 (2), 337-348, 2002 | 999 | 2002 |
Alternative lengthening of telomeres: models, mechanisms and implications AJ Cesare, RR Reddel Nature reviews genetics 11 (5), 319-330, 2010 | 867 | 2010 |
Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops AJ Cesare, JD Griffith Molecular and cellular biology 24 (22), 9948-9957, 2004 | 374 | 2004 |
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro VP Bermudez, LA Lindsey-Boltz, AJ Cesare, Y Maniwa, JD Griffith, ... Proceedings of the National Academy of Sciences 100 (4), 1633-1638, 2003 | 368 | 2003 |
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions AJ Cesare, Z Kaul, SB Cohen, CE Napier, HA Pickett, AA Neumann, ... Nature structural & molecular biology 16 (12), 1244, 2009 | 220 | 2009 |
Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis M Martin, J Cho, AJ Cesare, JD Griffith, G Attardi Cell 123 (7), 1227-1240, 2005 | 205 | 2005 |
Control of telomere length by a trimming mechanism that involves generation of t‐circles HA Pickett, AJ Cesare, RL Johnston, AA Neumann, RR Reddel The EMBO journal 28 (7), 799-809, 2009 | 195 | 2009 |
Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres ZH Zhong, WQ Jiang, AJ Cesare, AA Neumann, R Wadhwa, RR Reddel Journal of Biological Chemistry 282 (40), 29314-29322, 2007 | 189 | 2007 |
Five dysfunctional telomeres predict onset of senescence in human cells Z Kaul, AJ Cesare, LI Huschtscha, AA Neumann, RR Reddel EMBO reports, 2011 | 183 | 2011 |
Telomere uncapping and alternative lengthening of telomeres AJ Cesare, RR Reddel Mechanisms of ageing and development 129 (1-2), 99-108, 2008 | 161 | 2008 |
Telomere looping in P. sativum (common garden pea) AJ Cesare, N Quinney, S Willcox, D Subramanian, JD Griffith The Plant Journal 36 (2), 271-279, 2003 | 147 | 2003 |
A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest MT Hayashi, AJ Cesare, JAJ Fitzpatrick, E Lazzerini-Denchi, J Karlseder Nature structural & molecular biology 19 (4), 387, 2012 | 146 | 2012 |
The telomere deprotection response is functionally distinct from the genomic DNA damage response AJ Cesare, MT Hayashi, L Crabbe, J Karlseder Molecular cell 51 (2), 141-155, 2013 | 132 | 2013 |
The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats N Fouché, AJ Cesare, S Willcox, S Özgür, SA Compton, JD Griffith Journal of Biological Chemistry 281 (49), 37486-37495, 2006 | 114 | 2006 |
Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells SA Compton, JH Choi, AJ Cesare, S Özgür, JD Griffith Cancer research 67 (4), 1513-1519, 2007 | 107 | 2007 |
Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly L Crabbe, AJ Cesare, JM Kasuboski, JAJ Fitzpatrick, J Karlseder Cell reports 2 (6), 1521-1529, 2012 | 94 | 2012 |
Cell death during crisis is mediated by mitotic telomere deprotection MT Hayashi, AJ Cesare, T Rivera, J Karlseder Nature 522 (7557), 492-496, 2015 | 83 | 2015 |
A three-state model of telomere control over human proliferative boundaries AJ Cesare, J Karlseder Current opinion in cell biology 24 (6), 731-738, 2012 | 79 | 2012 |
Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain AJ Cesare, C Groff-Vindman, SA Compton, MJ McEachern, JD Griffith Molecular and cellular biology 28 (1), 20-29, 2008 | 71 | 2008 |
Recombination at long mutant telomeres produces tiny single-and double-stranded telomeric circles C Groff-Vindman, AJ Cesare, S Natarajan, JD Griffith, MJ McEachern Molecular and Cellular Biology 25 (11), 4406-4412, 2005 | 60 | 2005 |