Professor of Biochemistry and Molecular Biology, Universitat Pompeu Fabra, Barcelona. Spain
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Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1–YPD1–SSK1 “two-component” osmosensor
F Posas, SM Wurgler-Murphy, T Maeda, EA Witten, TC Thai, H Saito
Cell 86 (6), 865-875, 1996
Controlling gene expression in response to stress
E De Nadal, G Ammerer, F Posas
Nature Reviews Genetics 12 (12), 833-845, 2011
Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK
F Posas, H Saito
Science 276 (5319), 1702-1705, 1997
Response to hyperosmotic stress
H Saito, F Posas
Genetics 192 (2), 289-318, 2012
The transcriptional response of yeast to saline stress
F Posas, JR Chambers, JA Heyman, JP Hoeffler, E De Nadal, J Arino
Journal of Biological Chemistry 275 (23), 17249-17255, 2000
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1
P Ferrigno, F Posas, D Koepp, H Saito, PA Silver
The EMBO journal 17 (19), 5606-5614, 1998
Distributed biological computation with multicellular engineered networks
S Regot, J Macia, N Conde, K Furukawa, J Kjellén, T Peeters, S Hohmann, ...
Nature 469 (7329), 207-211, 2011
The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes
E De Nadal, M Zapater, PM Alepuz, L Sumoy, G Mas, F Posas
Nature 427 (6972), 370-374, 2004
Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two‐component response regulator
F Posas, H Saito
The EMBO journal, 1998
Yeast Cdc42 GTPase and Ste20 PAK‐like kinase regulate Sho1‐dependent activation of the Hog1 MAPK pathway
DC Raitt, F Posas, H Saito
The EMBO journal, 2000
The p38 pathway: from biology to cancer therapy
A Martínez-Limón, M Joaquin, M Caballero, F Posas, E De Nadal
International journal of molecular sciences 21 (6), 1913, 2020
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
M Proft, A Pascual‐Ahuir, E De Nadal, J Ariño, R Serrano, F Posas
The EMBO journal, 2001
3D-printing of transparent bio-microfluidic devices in PEG-DA
A Urrios, C Parra-Cabrera, N Bhattacharjee, AM Gonzalez-Suarez, ...
Lab on a Chip 16 (12), 2287-2294, 2016
Dealing with osmostress through MAP kinase activation
E De Nadal, PM Alepuz, F Posas
EMBO reports, 2002
Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1
X Escoté, M Zapater, J Clotet, F Posas
Nature cell biology 6 (10), 997-1002, 2004
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress‐induced activation of the p38 and JNK pathways
M Takekawa, F Posas, H Saito
The EMBO journal, 1997
Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II
PM Alepuz, E de Nadal, M Zapater, G Ammerer, F Posas
The EMBO journal 22 (10), 2433-2442, 2003
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress
C Bermejo, E Rodríguez, R García, JM Rodríguez-Peña, ...
Molecular biology of the cell 19 (3), 1113-1124, 2008
Signal transduction by MAP kinase cascades in budding yeast
F Posas, M Takekawa, H Saito
Current opinion in microbiology 1 (2), 175-182, 1998
The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast
M Thorsen, Y Di, C Tängemo, M Morillas, D Ahmadpour, C Van der Does, ...
Molecular biology of the cell 17 (10), 4400-4410, 2006
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