| FcRn: the neonatal Fc receptor comes of age DC Roopenian, S Akilesh Nature reviews immunology 7 (9), 715-725, 2007 | 2588 | 2007 |
| Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6 K Ozaki, R Spolski, R Ettinger, HP Kim, G Wang, CF Qi, P Hwu, DJ Shaffer, ... The Journal of Immunology 173 (9), 5361-5371, 2004 | 825 | 2004 |
| Enhanced antibody half-life improves in vivo activity J Zalevsky, AK Chamberlain, HM Horton, S Karki, IWL Leung, TJ Sproule, ... Nature biotechnology 28 (2), 157-159, 2010 | 745 | 2010 |
| The major histocompatibility complex–related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan C Chaudhury, S Mehnaz, JM Robinson, WL Hayton, DK Pearl, ... The Journal of experimental medicine 197 (3), 315-322, 2003 | 701 | 2003 |
| Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease SB Petkova, S Akilesh, TJ Sproule, GJ Christianson, H Al Khabbaz, ... International immunology 18 (12), 1759-1769, 2006 | 644 | 2006 |
| Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells M Yoshida, SM Claypool, JS Wagner, E Mizoguchi, A Mizoguchi, ... Immunity 20 (6), 769-783, 2004 | 533 | 2004 |
| The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs DC Roopenian, GJ Christianson, TJ Sproule, AC Brown, S Akilesh, ... The Journal of Immunology 170 (7), 3528-3533, 2003 | 514 | 2003 |
| CD4+ T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice PJ Baker, M Dixon, RT Evans, L Dufour, E Johnson, DC Roopenian Infection and immunity 67 (6), 2804-2809, 1999 | 440 | 1999 |
| Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant DV Serreze, EH Leiter, GJ Christianson, D Greiner, DC Roopenian Diabetes 43 (3), 505-509, 1994 | 408 | 1994 |
| A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice JA Bubier, TJ Sproule, O Foreman, R Spolski, DJ Shaffer, HC Morse III, ... Proceedings of the National Academy of Sciences 106 (5), 1518-1523, 2009 | 362 | 2009 |
| Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice PJ Baker, RT Evans, DC Roopenian Archives of oral biology 39 (12), 1035-1040, 1994 | 352 | 1994 |
| Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. SW Christianson, DL Greiner, RA Hesselton, JH Leif, EJ Wagar, ... Journal of immunology (Baltimore, Md.: 1950) 158 (8), 3578-3586, 1997 | 335 | 1997 |
| Podocytes use FcRn to clear IgG from the glomerular basement membrane S Akilesh, TB Huber, H Wu, G Wang, B Hartleben, JB Kopp, JH Miner, ... Proceedings of the National Academy of Sciences 105 (3), 967-972, 2008 | 305 | 2008 |
| Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism S Akilesh, GJ Christianson, DC Roopenian, AS Shaw The Journal of Immunology 179 (7), 4580-4588, 2007 | 299 | 2007 |
| Dependence of antibody-mediated presentation of antigen on FcRn SW Qiao, K Kobayashi, FE Johansen, LM Sollid, JT Andersen, E Milford, ... Proceedings of the National Academy of Sciences 105 (27), 9337-9342, 2008 | 294 | 2008 |
| The molecular and functional characterization of a dominant minor H antigen, H60 S Malarkannan, PP Shih, PA Eden, T Horng, AR Zuberi, G Christianson, ... The Journal of Immunology 161 (7), 3501-3509, 1998 | 289 | 1998 |
| Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases N Li, M Zhao, J Hilario-Vargas, P Prisayanh, S Warren, LA Diaz, ... The Journal of clinical investigation 115 (12), 3440-3450, 2005 | 281 | 2005 |
| Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria M Yoshida, K Kobayashi, TT Kuo, L Bry, JN Glickman, SM Claypool, ... The Journal of clinical investigation 116 (8), 2142-2151, 2006 | 266 | 2006 |
| Maternal IL-11Rα function is required for normal decidua and fetoplacental development in mice P Bilinski, D Roopenian, A Gossler Genes & development 12 (14), 2234-2243, 1998 | 248 | 1998 |
| The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease S Akilesh, S Petkova, TJ Sproule, DJ Shaffer, GJ Christianson, ... The Journal of clinical investigation 113 (9), 1328-1333, 2004 | 233 | 2004 |
