| An aggregation advisor for ligand discovery JJ Irwin, D Duan, H Torosyan, AK Doak, KT Ziebart, T Sterling, ... Journal of medicinal chemistry 58 (17), 7076-7087, 2015 | 405 | 2015 |
| The activities of drug inactive ingredients on biological targets J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ... Science 369 (6502), 403-413, 2020 | 69 | 2020 |
| Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ... Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018 | 66 | 2018 |
| Stable colloidal drug aggregates catch and release active enzymes CK McLaughlin, D Duan, AN Ganesh, H Torosyan, BK Shoichet, ... ACS chemical biology 11 (4), 992-1000, 2016 | 46 | 2016 |
| Internal structure and preferential protein binding of colloidal aggregates D Duan, H Torosyan, D Elnatan, CK McLaughlin, J Logie, MS Shoichet, ... ACS chemical biology 12 (1), 282-290, 2017 | 32 | 2017 |
| Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma N Jin, B Keam, J Cho, MJ Lee, HR Kim, H Torosyan, N Jura, PKS Ng, ... The Journal of clinical investigation 131 (22), 2021 | 25 | 2021 |
| Identification of novel smoothened ligands using structure-based docking C Lacroix, I Fish, H Torosyan, P Parathaman, JJ Irwin, BK Shoichet, ... PLoS One 11 (8), e0160365, 2016 | 25 | 2016 |
| Protein stability effects in aggregate-based enzyme inhibition H Torosyan, BK Shoichet Journal of medicinal chemistry 62 (21), 9593-9599, 2019 | 21 | 2019 |
| Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors J Sgrignani, F De Luca, H Torosyan, JD Docquier, D Duan, B Novati, ... Journal of computer-aided molecular design 30, 851-861, 2016 | 13 | 2016 |
| Robust sequence determinants of α-synuclein toxicity in yeast implicate membrane binding RW Newberry, T Arhar, J Costello, GC Hartoularos, AM Maxwell, ... ACS chemical biology 15 (8), 2137-2153, 2020 | 11 | 2020 |
| Triggered release enhances the cytotoxicity of stable colloidal drug aggregates EN Donders, AN Ganesh, H Torosyan, P Lak, BK Shoichet, MS Shoichet ACS chemical biology 14 (7), 1507-1514, 2019 | 9 | 2019 |
| CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids M Lo, A Sharir, MD Paul, H Torosyan, C Agnew, A Li, C Neben, ... Nature communications 13 (1), 2407, 2022 | 5 | 2022 |
| Piquing our interest: Insights into the role of PEAK3 in signaling and disease MD Paul, H Torosyan, N Jura Science signaling 15 (722), eabm9396, 2022 | 2 | 2022 |
| Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3 H Torosyan, MD Paul, A Forget, M Lo, D Diwanji, K Pawłowski, NJ Krogan, ... Nature communications 14 (1), 3543, 2023 | | 2023 |
| Stable colloidal drug aggregates and methods of manufacture and use thereof MS Shoichet, AN Ganesh, EN Donders, BK Shoichet, H Torosyan US Patent App. 17/619,837, 2022 | | 2022 |
