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Ryan N. Ptashkin
Ryan N. Ptashkin
Department of Computational Medicine and Bioinformatics, University of Michigan
Verifierad e-postadress på umich.edu
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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
A Zehir, R Benayed, RH Shah, A Syed, S Middha, HR Kim, P Srinivasan, ...
Nature medicine 23 (6), 703-713, 2017
29362017
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ...
Nature genetics 52 (11), 1219-1226, 2020
4372020
Comprehensive molecular profiling of intrahepatic and extrahepatic cholangiocarcinomas: potential targets for intervention
MA Lowery, R Ptashkin, E Jordan, MF Berger, A Zehir, M Capanu, ...
Clinical Cancer Research 24 (17), 4154-4161, 2018
4192018
High yield of RNA sequencing for targetable kinase fusions in lung adenocarcinomas with no mitogenic driver alteration detected by DNA sequencing and low tumor mutation burden
R Benayed, M Offin, K Mullaney, P Sukhadia, K Rios, P Desmeules, ...
Clinical Cancer Research 25 (15), 4712-4722, 2019
3482019
First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
YY Janjigian, SB Maron, WK Chatila, B Millang, SS Chavan, C Alterman, ...
The Lancet Oncology 21 (6), 821-831, 2020
2982020
SMARCA4-deficient thoracic sarcomatoid tumors represent primarily smoking-related undifferentiated carcinomas rather than primary thoracic sarcomas
N Rekhtman, J Montecalvo, JC Chang, D Alex, RN Ptashkin, N Ai, ...
Journal of Thoracic Oncology 15 (2), 231-247, 2020
2112020
Real-time genomic profiling of pancreatic ductal adenocarcinoma: potential actionability and correlation with clinical phenotype
MA Lowery, EJ Jordan, O Basturk, RN Ptashkin, A Zehir, MF Berger, ...
Clinical Cancer Research 23 (20), 6094-6100, 2017
1822017
Resistance to TRK inhibition mediated by convergent MAPK pathway activation
E Cocco, AM Schram, A Kulick, S Misale, HH Won, R Yaeger, P Razavi, ...
Nature medicine 25 (9), 1422-1427, 2019
1792019
Respiratory syncytial virus utilizes a tRNA fragment to suppress antiviral responses through a novel targeting mechanism
J Deng, RN Ptashkin, Y Chen, Z Cheng, G Liu, T Phan, X Deng, J Zhou, ...
Molecular Therapy 23 (10), 1622-1629, 2015
1612015
Prevalence of clonal hematopoiesis mutations in tumor-only clinical genomic profiling of solid tumors
RN Ptashkin, DL Mandelker, CC Coombs, K Bolton, Z Yelskaya, ...
JAMA oncology 4 (11), 1589-1593, 2018
1572018
Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli
C Raeside, J Gaffé, DE Deatherage, O Tenaillon, AM Briska, RN Ptashkin, ...
MBio 5 (5), 10.1128/mbio. 01377-14, 2014
1392014
Clonal hematopoiesis is associated with risk of severe Covid-19
KL Bolton, Y Koh, MB Foote, H Im, J Jee, CH Sun, A Safonov, R Ptashkin, ...
Nature communications 12 (1), 5975, 2021
982021
DNA methylation-based classification of sinonasal undifferentiated carcinoma
S Dogan, V Vasudevaraja, B Xu, J Serrano, RN Ptashkin, HJ Jung, ...
Modern Pathology 32 (10), 1447-1459, 2019
972019
Frequent IDH2 R172 mutations in undifferentiated and poorly‐differentiated sinonasal carcinomas
S Dogan, DJ Chute, B Xu, RN Ptashkin, R Chandramohan, ...
The Journal of pathology 242 (4), 400-408, 2017
942017
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
A Rose Brannon, G Jayakumaran, M Diosdado, J Patel, A Razumova, ...
Nature Communications 12 (1), 3770, 2021
852021
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis
T Gao, R Ptashkin, KL Bolton, M Sirenko, C Fong, B Spitzer, ...
Nature communications 12 (1), 338, 2021
802021
Mammary analog secretory carcinoma of the thyroid gland: a primary thyroid adenocarcinoma harboring ETV6–NTRK3 fusion
S Dogan, L Wang, RN Ptashkin, RR Dawson, JP Shah, EJ Sherman, ...
Modern Pathology 29 (9), 985-995, 2016
792016
Clinicopathologic and genetic characterization of nonacute NPM1-mutated myeloid neoplasms
SS Patel, C Ho, RN Ptashkin, S Sadigh, A Bagg, JT Geyer, ML Xu, ...
Blood Advances 3 (9), 1540-1545, 2019
522019
The clinical management of clonal hematopoiesis: creation of a clonal hematopoiesis clinic
KL Bolton, A Zehir, RN Ptashkin, M Patel, D Gupta, R Sidlow, ...
Hematology/Oncology Clinics 34 (2), 357-367, 2020
472020
Fragment size analysis may distinguish clonal hematopoiesis from tumor-derived mutations in cell-free DNA
F Marass, D Stephens, R Ptashkin, A Zehir, MF Berger, DB Solit, ...
Clinical chemistry 66 (4), 616-618, 2020
412020
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Artiklar 1–20