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Christopher O'Shea
Christopher O'Shea
Verified email at bham.ac.uk
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Year
ElectroMap: high-throughput open-source software for analysis and mapping of cardiac electrophysiology
C O’Shea, AP Holmes, TY Yu, J Winter, SP Wells, J Correia, BJ Boukens, ...
Scientific reports 9 (1), 1389, 2019
692019
Cardiac optogenetics and optical mapping–overcoming spectral congestion in all-optical cardiac electrophysiology
C O’shea, AP Holmes, J Winter, J Correia, X Ou, P Kirchhof, L Fabritz, ...
Frontiers in physiology 10, 430706, 2019
522019
Cardiac optical mapping–State-of-the-art and future challenges
C O’Shea, SN Kabir, AP Holmes, M Lei, L Fabritz, K Rajpoot, D Pavlovic
The international journal of biochemistry & cell biology 126, 105804, 2020
382020
Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca2+ transients in murine heart
Q Wen, K Gandhi, RA Capel, G Hao, C O'Shea, G Neagu, S Pearcey, ...
The Journal of Physiology 596 (17), 3951-3965, 2018
382018
Sympathetic nervous regulation of calcium and action potential alternans in the intact heart
J Winter, MJ Bishop, CDE Wilder, C O'Shea, D Pavlovic, MJ Shattock
Frontiers in physiology 9, 16, 2018
222018
Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets
C Pallini, JA Pike, C O’Shea, RK Andrews, EE Gardiner, SP Watson, ...
Platelets 32 (1), 59-73, 2021
182021
Anti‐GPVI nanobody blocks collagen‐and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation
NJ Jooss, CW Smith, A Slater, SJ Montague, Y Di, C O'shea, MR Thomas, ...
Journal of Thrombosis and Haemostasis 20 (11), 2617-2631, 2022
172022
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone
AP Holmes, P Saxena, SN Kabir, C O’Shea, SM Kuhlmann, S Gupta, ...
Heart Rhythm 18 (7), 1212-1220, 2021
162021
Effects of genetic background, sex, and age on murine atrial electrophysiology
J Obergassel, M O’Reilly, LC Sommerfeld, SN Kabir, C O’Shea, F Syeda, ...
EP Europace 23 (6), 958-969, 2021
142021
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels
S O'Brien, AP Holmes, DM Johnson, SN Kabir, C O'Shea, M O'Reilly, ...
Journal of Molecular and Cellular Cardiology 166, 23-35, 2022
132022
High-throughput analysis of optical mapping data using ElectroMap
C O’Shea, AP Holmes, YY Ting, J Winter, SP Wells, BA Parker, D Fobian, ...
JoVE (Journal of Visualized Experiments), e59663, 2019
132019
High resolution optical mapping of cardiac electrophysiology in pre-clinical models
C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ...
Scientific Data 9 (1), 135, 2022
112022
A protocol for dual calcium-voltage optical mapping in murine sinoatrial preparation with optogenetic pacing
R Dong, R Mu-U-Min, AJM Reith, C O’Shea, S He, K Duan, K Kou, ...
Frontiers in physiology 10, 954, 2019
112019
A protocol for transverse cardiac slicing and optical mapping in murine heart
S He, Q Wen, C O’Shea, R Mu-U-Min, K Kou, A Grassam-Rowe, Y Liu, ...
Frontiers in Physiology 10, 441705, 2019
102019
Examination of the effects of conduction slowing on the upstroke of optically recorded action potentials
C O’Shea, D Pavlovic, K Rajpoot, J Winter
Frontiers in physiology 10, 475399, 2019
92019
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide
M O’Reilly, LC Sommerfeld, C O’Shea, S Broadway-Stringer, S Andaleeb, ...
Europace 25 (3), 1152-1161, 2023
82023
Generation of cardiomyocytes from human-induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists
FS Ahmad, Y Jin, A Grassam-Rowe, Y Zhou, M Yuan, X Fan, R Zhou, ...
Philosophical Transactions of the Royal Society B 378 (1879), 20220312, 2023
72023
Basic research approaches to evaluate cardiac arrhythmia in heart failure and beyond
MJ Cumberland, LL Riebel, A Roy, C O’Shea, AP Holmes, C Denning, ...
Frontiers in Physiology 13, 806366, 2022
62022
Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity
C O’Shea, J Winter, AP Holmes, DM Johnson, JN Correia, P Kirchhof, ...
Progress in biophysics and molecular biology 157, 84-93, 2020
62020
A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts
S He, K Kou, C O’shea, T Chen, R Mu-U-Min, R Dong, H Ren, X Zhou, ...
Scientific Data 8 (1), 314, 2021
42021
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