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| Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self J Derbinski, A Schulte, B Kyewski, L Klein Nature immunology 2 (11), 1032-1039, 2001 | 1395 | 2001 |
| A central role for central tolerance B Kyewski, L Klein Annu. Rev. Immunol. 24, 571-606, 2006 | 967 | 2006 |
| Antigen presentation in the thymus for positive selection and central tolerance induction L Klein, M Hinterberger, G Wirnsberger, B Kyewski Nature Reviews Immunology 9 (12), 833-844, 2009 | 798 | 2009 |
| Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels J Derbinski, J Gäbler, B Brors, S Tierling, S Jonnakuty, M Hergenhahn, ... The Journal of experimental medicine 202 (1), 33-45, 2005 | 711 | 2005 |
| Two genetically separable steps in the differentiation of thymic epithelium M Nehls, B Kyewski, M Messerle, R Waldschütz, K Schüddekopf, ... Science 272 (5263), 886-889, 1996 | 528 | 1996 |
| Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells L Klein, M Klugmann, KA Nave, VK Tuohy, B Kyewski Nature medicine 6 (1), 56-61, 2000 | 479 | 2000 |
| Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters J Gotter, B Brors, M Hergenhahn, B Kyewski The Journal of experimental medicine 199 (2), 155-166, 2004 | 462 | 2004 |
| Self-representation in the thymus: an extended view B Kyewski, J Derbinski Nature Reviews Immunology 4 (9), 688-698, 2004 | 451 | 2004 |
| Bone marrow as a priming site for T-cell responses to blood-borne antigen M Feuerer, P Beckhove, N Garbi, Y Mahnke, A Limmer, M Hommel, ... Nature medicine 9 (9), 1151-1157, 2003 | 392 | 2003 |
| The thymic medulla: a unique microenvironment for intercellular self-antigen transfer C Koble, B Kyewski Journal of Experimental Medicine 206 (7), 1505-1513, 2009 | 312 | 2009 |
| Thymic B cells are licensed to present self antigens for central T cell tolerance induction T Yamano, J Nedjic, M Hinterberger, M Steinert, S Koser, S Pinto, ... Immunity 42 (6), 1048-1061, 2015 | 294 | 2015 |
| Promiscuous gene expression and central T-cell tolerance: more than meets the eye B Kyewski, J Derbinski, J Gotter, L Klein Trends in immunology 23 (7), 364-371, 2002 | 250 | 2002 |
| Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development CN Miller, I Proekt, J von Moltke, KL Wells, AR Rajpurkar, H Wang, ... Nature 559 (7715), 627-631, 2018 | 248 | 2018 |
| Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism J Derbinski, S Pinto, S Rösch, K Hexel, B Kyewski Proceedings of the National Academy of Sciences 105 (2), 657-662, 2008 | 231 | 2008 |
| CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium L Klein, T Klein, U Rüther, B Kyewski The Journal of experimental medicine 188 (1), 5-16, 1998 | 217 | 1998 |
| An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus M Giraud, R Taubert, C Vandiedonck, X Ke, M Lévi-Strauss, F Pagani, ... Nature 448 (7156), 934-937, 2007 | 214 | 2007 |
| Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans HJ Lv, E Havari, S Pinto, RV Gottumukkala, L Cornivelli, K Raddassi, ... The Journal of clinical investigation 121 (4), 1561-1573, 2011 | 213 | 2011 |
| A filarial cysteine protease inhibitor down‐regulates T cell proliferation and enhances interleukin‐10 production S Hartmann, B Kyewski, B Sonnenburg, R Lucius European journal of immunology 27 (9), 2253-2260, 1997 | 196 | 1997 |
| Programmed cell death is affected in the novel mouse mutant Fused toes (Ft) F Hoeven, T Schimmang, A Volkmann, MG Mattei, B Kyewski, U Rüther Development 120 (9), 2601-2607, 1994 | 195 | 1994 |
