| Sphingosine 1-phosphate and cancer NJ Pyne, S Pyne Nature Reviews Cancer 10 (7), 489, 2010 | 977 | 2010 |
| Sphingosine 1-phosphate signalling in mammalian cells S Pyne, NJ Pyne Biochem J 349, 385-402, 2000 | 938 | 2000 |
| The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors S Alexander British Journal of Pharmacology 170, 1449-1458, 2013 | 643 | 2013 |
| The concise guide to pharmacology 2019/20: Enzymes SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ... British Journal of Pharmacology 176, S297-S396, 2019 | 497 | 2019 |
| The concise guide to pharmacology 2021/22: Enzymes SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ... British journal of pharmacology 178, S313-S411, 2021 | 367 | 2021 |
| Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors S Pyne, N Pyne Pharmacology & Therapeutics 88 (2), 115-131, 2000 | 241 | 2000 |
| FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen … F Tonelli, KG Lim, C Loveridge, J Long, SM Pitson, G Tigyi, R Bittman, ... Cellular Signalling 22 (10), 1536-1542, 2010 | 225 | 2010 |
| High expression of sphingosine 1-phosphate receptors, S1P 1 and S1P 3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of … C Watson, JS Long, C Orange, CL Tannahill, E Mallon, LM McGlynn, ... The American Journal of Pathology 177 (5), 2205-2215, 2010 | 199 | 2010 |
| Tethering of the platelet-derived growth factorbeta receptor to G-protein coupled receptors: A novel platform for integrative signaling by these receptor classes in mammalian cells F Alderton, S Rakhit, KK Choi, T Palmer, B Sambi, S Pyne, NJ Pyne Journal of Biological Chemistry 276, 28578-28585, 2001 | 194 | 2001 |
| Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances S Pyne, DR Adams, NJ Pyne Progress in Lipid Research 62, 93-106, 2016 | 191 | 2016 |
| The Concise Guide to PHARMACOLOGY 2013/14: Overview SPH Alexander, HE Benson, E Faccenda, AJ Pawson, JL Sharman, ... British Journal of Pharmacology 170 (8), 1449-1458, 2013 | 183 | 2013 |
| Increased expression of the cGMP‐inhibited cAMP‐specific (PDE3) and cGMP binding cGMP‐specific (PDE5) phosphodiesterases in models of pulmonary hypertension F Murray, MR MacLean, NJ Pyne British Journal of Pharmacology 137 (8), 1187-1194, 2002 | 159 | 2002 |
| Sphingosine 1-phosphate signalling in cancer NJ Pyne, F Tonelli, KG Lim, JS Long, J Edwards, S Pyne Biochemical Society Transactions 40 (1), 94-100, 2012 | 154 | 2012 |
| Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease S Pyne, SC Lee, J Long, NJ Pyne Cellular Signalling 21 (1), 14-21, 2009 | 151 | 2009 |
| Platelet derived growth factor stimulation of the p42/p44 mitogen activated protein kinase pathway in airway smooth muscle: Role of pertussis toxin-sensitive G-proteins … AM Conway, S Rakhit, S Pyne, NJ Pyne Biochem J 337, 171-177, 1999 | 150 | 1999 |
| FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation and actin rearrangement in MCF-7 breast cancer cells KG Lim, F Tonelli, Z Li, X Lu, R Bittman, S Pyne, NJ Pyne Journal of Biological Chemistry 286, 18633-18640, 2011 | 148 | 2011 |
| Sphingomyelin‐derived lipids differentially regulate the extracellular signal‐regulated kinase 2 (ERK‐2) and c‐Jun N‐terminal kinase (JNK) signal cascades in airway smooth muscle S Pyne, J Chapman, L Steele, NJ Pyne European journal of biochemistry 237 (3), 819-826, 1996 | 146 | 1996 |
| Role of sphingosine 1-phosphate receptors, sphingosine kinases and sphingosine in cancer and inflammation NJ Pyne, M McNaughton, S Boomkamp, N MacRitchie, C Evangelisti, ... Advances in Biological Regulation 60, 151-159, 2016 | 144 | 2016 |
| Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGFβ receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells C Waters, B Sambi, KC Kong, D Thompson, SM Pitson, S Pyne, NJ Pyne Journal of Biological Chemistry 278 (8), 6282-6290, 2003 | 143 | 2003 |
| The sphingosine kinase 1 inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells C Loveridge, F Tonelli, T Leclercq, KG Lim, JS Long, E Berdyshev, ... Journal of Biological Chemistry, 38841-38852, 2010 | 142 | 2010 |
Susan PyneProfessor, University of StrathclydeVerified email at strath.ac.uk
