Michael Crichton
Michael Crichton
Institute of Mechanical, Process and Energy Engineering, Heriot-Watt University, Edinburgh, UK
Verifierad e-postadress på hw.ac.uk - Startsida
Citeras av
Citeras av
Nanopatch‐targeted skin vaccination against West Nile virus and chikungunya virus in mice
TW Prow, X Chen, NA Prow, GJP Fernando, CSE Tan, AP Raphael, ...
Small 6 (16), 1776-1784, 2010
Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
X Chen, TW Prow, ML Crichton, DWK Jenkins, MS Roberts, IH Frazer, ...
Journal of Controlled Release 139 (3), 212-220, 2009
Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model
GJP Fernando, X Chen, TW Prow, ML Crichton, EJ Fairmaid, MS Roberts, ...
PloS one 5 (4), e10266, 2010
Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model
GJP Fernando, X Chen, TW Prow, ML Crichton, EJ Fairmaid, MS Roberts, ...
PloS one 5 (4), e10266, 2010
Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization
X Chen, GJP Fernando, ML Crichton, C Flaim, SR Yukiko, EJ Fairmaid, ...
Journal of controlled release 152 (3), 349-355, 2011
Targeted, needle‐free vaccinations in skin using multilayered, densely‐packed dissolving microprojection arrays
AP Raphael, TW Prow, ML Crichton, X Chen, GJP Fernando, ...
Small 6 (16), 1785-1793, 2010
The effect of strain rate on the precision of penetration of short densely-packed microprojection array patches coated with vaccine
ML Crichton, A Ansaldo, X Chen, TW Prow, GJP Fernando, MAF Kendall
Biomaterials 31 (16), 4562-4572, 2010
The viscoelastic, hyperelastic and scale dependent behaviour of freshly excised individual skin layers
ML Crichton, BC Donose, X Chen, AP Raphael, H Huang, MAF Kendall
Biomaterials 32 (20), 4670-4681, 2011
Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays
X Chen, AS Kask, ML Crichton, C McNeilly, S Yukiko, L Dong, ...
Journal of controlled release 148 (3), 327-333, 2010
Dry-coated live viral vector vaccines delivered by nanopatch microprojections retain long-term thermostability and induce transgene-specific T cell responses in mice
FE Pearson, CL McNeilly, ML Crichton, CA Primiero, SR Yukiko, ...
PloS one 8 (7), e67888, 2013
Surface-modified microprojection arrays for intradermal biomarker capture, with low non-specific protein binding
SR Corrie, GJP Fernando, ML Crichton, MEG Brunck, CD Anderson, ...
Lab on a Chip 10 (20), 2655-2658, 2010
Elastic modulus and viscoelastic properties of full thickness skin characterised at micro scales
ML Crichton, X Chen, H Huang, MAF Kendall
Biomaterials 34 (8), 2087-2097, 2013
Formulations for microprojection/microneedle vaccine delivery: Structure, strength and release profiles
AP Raphael, ML Crichton, RJ Falconer, S Meliga, X Chen, GJP Fernando, ...
Journal of Controlled Release 225, 40-52, 2016
Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans
JCJ Wei, GA Edwards, DJ Martin, H Huang, ML Crichton, MAF Kendall
Scientific reports 7 (1), 1-16, 2017
Inactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses
DA Muller, FE Pearson, GJP Fernando, C Agyei-Yeboah, NS Owens, ...
Scientific reports 6, 22094, 2016
The hyperelastic and failure behaviors of skin in relation to the dynamic application of microscopic penetrators in a murine model
SC Meliga, JW Coffey, ML Crichton, C Flaim, M Veidt, MAF Kendall
Acta biomaterialia 48, 341-356, 2017
Microprojection arrays to immunise at mucosal surfaces
CL McNeilly, ML Crichton, CA Primiero, IH Frazer, MS Roberts, ...
Journal of Controlled Release 196, 252-260, 2014
Delivery device
MAF Kendall, S Meliga, ACI Depelsenaire, ML Crichton, C Flaim
US Patent App. 14/351,499, 2014
The changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunization
ML Crichton, DA Muller, ACI Depelsenaire, FE Pearson, J Wei, J Coffey, ...
Scientific reports 6 (1), 1-8, 2016
Patch applying apparatus
MAF Kendall, AB Ansaldo, ML Crichton, RJ Falconer
US Patent 9,943,673, 2018
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Artiklar 1–20