| A simple and efficient method to reduce nontemplated nucleotide addition at the 3′ terminus of RNAs transcribed by T7 RNA polymerase C Kao, M Zheng, S Rüdisser Rna 5 (9), 1268-1272, 1999 | 364 | 1999 |
| Library design for fragment based screening A Schuffenhauer, S Ruedisser, A Marzinzik, W Jahnke, P Selzer, ... Current topics in medicinal chemistry 5 (8), 751-762, 2005 | 262 | 2005 |
| Spin label enhanced NMR screening W Jahnke, S Rüdisser, M Zurini Journal of the American Chemical Society 123 (13), 3149-3150, 2001 | 175 | 2001 |
| Solution structure of cobalt (III) hexammine complexed to the GAAA tetraloop, and metal-ion binding to G· A mismatches S Rüdisser, I Tinoco Jr Journal of molecular biology 295 (5), 1211-1223, 2000 | 140 | 2000 |
| Structural basis of a small molecule targeting RNA for a specific splicing correction S Campagne, S Boigner, S Rüdisser, A Moursy, L Gillioz, A Knörlein, ... Nature chemical biology 15 (12), 1191-1198, 2019 | 114 | 2019 |
| Nuclear magnetic resonance of hyperpolarized fluorine for characterization of protein–ligand interactions Y Lee, H Zeng, S Ruedisser, AD Gossert, C Hilty Journal of the American Chemical Society 134 (42), 17448-17451, 2012 | 100 | 2012 |
| A simple and efficient method to transcribe RNAs with reduced 3′ heterogeneity C Kao, S Rüdisser, M Zheng Methods 23 (3), 201-205, 2001 | 83 | 2001 |
| Small-molecule factor D inhibitors targeting the alternative complement pathway J Maibaum, SM Liao, A Vulpetti, N Ostermann, S Randl, S Rüdisser, ... Nature Chemical Biology 12 (12), 1105-1110, 2016 | 77 | 2016 |
| B-DNA's BI→ BII conformer substate dynamics is coupled with water migration RH Winger, KR Liedl, S Rüdisser, A Pichler, A Hallbrucker, E Mayer The Journal of Physical Chemistry B 102 (44), 8934-8940, 1998 | 62 | 1998 |
| Enthalpy, entropy, and structural relaxation behaviors of A-and B-DNA in their vitrified states and the effect of water on the dynamics of B-DNA S Rüdisser, A Hallbrucker, E Mayer, GP Johari The Journal of Physical Chemistry B 101 (2), 266-277, 1997 | 57 | 1997 |
| Fragment-based screening by biochemical assays: Systematic feasibility studies with trypsin and MMP12 A Boettcher, S Ruedisser, P Erbel, D Vinzenz, N Schiering, U Hassiepen, ... Journal of biomolecular screening 15 (9), 1029-1041, 2010 | 47 | 2010 |
| Unexpected BII conformer substate population in unoriented hydrated films of the d (CGCGAATTCGCG) 2 dodecamer and of native B-DNA from salmon testes A Pichler, S Rüdisser, M Mitterböck, CG Huber, RH Winger, KR Liedl, ... Biophysical journal 77 (1), 398-409, 1999 | 35 | 1999 |
| B-DNA's conformational substates revealed by Fourier transform infrared difference spectroscopy S Rüdisser, A Hallbrucker, E Mayer Journal of the American Chemical Society 119 (50), 12251-12256, 1997 | 35 | 1997 |
| Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo E Lorthiois, K Anderson, A Vulpetti, O Rogel, F Cumin, N Ostermann, ... Journal of medicinal chemistry 60 (13), 5717-5735, 2017 | 33 | 2017 |
| Hydrogen bonds in RNA base pairs investigated by cross-correlated relaxation of multiple-quantum coherence in NMR E Chiarparin, S Rudisser, G Bodenhausen ChemPhysChem 2 (1), 41-45, 2001 | 27 | 2001 |
| Probing DNA's dynamics and conformational substates by enthalpy relaxation and its recovery S Rüdisser, A Hallbrucker, E Mayer The Journal of Physical Chemistry 100 (2), 458-461, 1996 | 26 | 1996 |
| Structure-based library design and fragment screening for the identification of reversible complement factor D protease inhibitors A Vulpetti, S Randl, S Rüdisser, N Ostermann, P Erbel, A Mac Sweeney, ... Journal of Medicinal Chemistry 60 (5), 1946-1958, 2017 | 25 | 2017 |
| Azaindoles as Zinc‐Binding Small‐Molecule Inhibitors of the JAMM Protease CSN5 E Altmann, P Erbel, M Renatus, M Schaefer, A Schlierf, A Druet, L Kieffer, ... Angewandte Chemie 129 (5), 1314-1317, 2017 | 25 | 2017 |
| A Novel Class of Oral Direct Renin Inhibitors: Highly Potent 3,5-Disubstituted Piperidines Bearing a Tricyclic P3–P1 Pharmacophore N Ostermann, S Ruedisser, C Ehrhardt, W Breitenstein, A Marzinzik, ... Journal of medicinal chemistry 56 (6), 2196-2206, 2013 | 24 | 2013 |
| Nonoriented d(CGCGAATTCGCG)2 Dodecamer Persists in the B-Form Even at Low Water Activity A Pichler, S Rüdisser, RH Winger, KR Liedl, A Hallbrucker, E Mayer Journal of the American Chemical Society 122 (4), 716-717, 2000 | 24 | 2000 |
Klaus LiedlProfessor for Theoretical Chemistry, University of InnsbruckVerified email at uibk.ac.at
