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| Targeted expression of mutated ALK induces neuroblastoma in transgenic mice LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ... Science translational medicine 4 (141), 141ra91-141ra91, 2012 | 200 | 2012 |
| Functional Tuning of CARs Reveals Signaling Threshold above Which CD8+ CTL Antitumor Potency Is Attenuated due to Cell Fas–FasL-Dependent AICD A Künkele, AJ Johnson, LS Rolczynski, CA Chang, V Hoglund, ... Cancer immunology research 3 (4), 368-379, 2015 | 185 | 2015 |
| Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis NA Vitanza, AJ Johnson, AL Wilson, C Brown, JK Yokoyama, A Künkele, ... Nature medicine 27 (9), 1544-1552, 2021 | 167 | 2021 |
| The immune landscape of neuroblastoma: challenges and opportunities for novel therapeutic strategies in pediatric oncology J Wienke, MP Dierselhuis, GAM Tytgat, A Künkele, S Nierkens, ... European journal of cancer 144, 123-150, 2021 | 125 | 2021 |
| MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells JH Schulte, S Lindner, A Bohrer, J Maurer, K De Preter, S Lefever, ... Oncogene 32 (8), 1059-1065, 2013 | 123 | 2013 |
| Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia MA Weber, H Krakowski-Roosen, L Schröder, R Kinscherf, M Krix, ... Acta Oncologica 48 (1), 116-124, 2009 | 116 | 2009 |
| Preclinical assessment of CD171-directed CAR T-cell adoptive therapy for childhood neuroblastoma: CE7 epitope target safety and product manufacturing feasibility A Künkele, A Taraseviciute, LS Finn, AJ Johnson, C Berger, O Finney, ... Clinical cancer research 23 (2), 466-477, 2017 | 114 | 2017 |
| Relationship of skeletal muscle perfusion measured by contrast‐enhanced ultrasonography to histologic microvascular density MA Weber, H Krakowski-Roosen, S Delorme, H Renk, M Krix, J Millies, ... Journal of ultrasound in medicine 25 (5), 583-591, 2006 | 77 | 2006 |
| Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas A Künkele, K De Preter, L Heukamp, T Thor, KW Pajtler, W Hartmann, ... Neuro-oncology 14 (7), 859-869, 2012 | 72 | 2012 |
| Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma V Arnhold, K Schmelz, J Proba, A Winkler, J Wünschel, J Toedling, ... Oncotarget 9 (2), 2304, 2018 | 65 | 2018 |
| Myoglobin plasma level related to muscle mass and fiber composition–a clinical marker of muscle wasting? MA Weber, R Kinscherf, H Krakowski-Roosen, M Aulmann, H Renk, ... Journal of molecular medicine 85, 887-896, 2007 | 63 | 2007 |
| CD171-and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing L Andersch, J Radke, A Klaus, S Schwiebert, A Winkler, E Schumann, ... BMC cancer 19, 1-17, 2019 | 56 | 2019 |
| Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions K Schmelz, J Toedling, M Huska, MC Cwikla, LM Kruetzfeldt, J Proba, ... Nature communications 12 (1), 6804, 2021 | 49 | 2021 |
| MiR‐34a deficiency accelerates medulloblastoma formation in vivo T Thor, A Künkele, KW Pajtler, AK Wefers, H Stephan, P Mestdagh, ... International Journal of Cancer 136 (10), 2293-2303, 2015 | 47 | 2015 |
| Long‐term follow‐up of pediatric patients receiving total body irradiation before hematopoietic stem cell transplantation and post‐transplant survival of> 2 years A Künkele, M Engelhard, BP Hauffa, U Mellies, C Müntjes, C Hüer, ... Pediatric blood & cancer 60 (11), 1792-1797, 2013 | 45 | 2013 |
| The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma KW Pajtler, C Weingarten, T Thor, A Künkele, LC Heukamp, R Büttner, ... Acta neuropathologica communications 1, 1-13, 2013 | 42 | 2013 |
| The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models KW Pajtler, N Sadowski, S Ackermann, K Althoff, K Schönbeck, K Batzke, ... Oncotarget 8 (4), 6730, 2017 | 41 | 2017 |
| MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma J Fabian, D Opitz, K Althoff, M Lodrini, B Hero, R Volland, A Beckers, ... Oncotarget 7 (41), 66344, 2016 | 37 | 2016 |
| Chemoreduction improves eye retention in patients with retinoblastoma: a report from the German Retinoblastoma Reference Centre A Künkele, C Jurklies, R Wieland, D Lohmann, N Bornfeld, A Eggert, ... British Journal of Ophthalmology 97 (10), 1277-1283, 2013 | 37 | 2013 |
