| Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69− CD56dim cells N Marquardt, E Kekäläinen, P Chen, E Kvedaraite, JN Wilson, ... Journal of allergy and clinical immunology 139 (4), 1321-1330. e4, 2017 | 138 | 2017 |
| IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways ML Manson, J Säfholm, A James, AK Johnsson, P Bergman, M Al-Ameri, ... Journal of Allergy and Clinical Immunology 145 (3), 808-817. e2, 2020 | 113 | 2020 |
| Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing L Mazzurana, P Czarnewski, V Jonsson, L Wigge, M Ringnér, TC Williams, ... Cell research 31 (5), 554-568, 2021 | 112 | 2021 |
| Prostaglandin E2 inhibits mast cell–dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor J Säfholm, ML Manson, J Bood, I Delin, AC Orre, P Bergman, M Al-Ameri, ... Journal of Allergy and Clinical Immunology 136 (5), 1232-1239. e1, 2015 | 103 | 2015 |
| The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea V Pulkkinen, ML Manson, J Säfholm, M Adner, SE Dahlén American Journal of Physiology-Lung Cellular and Molecular Physiology 303 …, 2012 | 86 | 2012 |
| Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle ML Manson, J Säfholm, M Al-Ameri, P Bergman, AC Orre, K Swärd, ... European journal of pharmacology 740, 302-311, 2014 | 63 | 2014 |
| PGE2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors J Säfholm, SE Dahlén, I Delin, K Maxey, K Stark, LO Cardell, M Adner British journal of pharmacology 168 (4), 794-806, 2013 | 52 | 2013 |
| Lipid mediator quantification in isolated human and guinea pig airways: an expanded approach for respiratory research J Kolmert, A Fauland, D Fuchs, J Säfholm, C Gómez, M Adner, ... Analytical chemistry 90 (17), 10239-10248, 2018 | 46 | 2018 |
| Divergent effects of acute and prolonged interleukin 33 exposure on mast cell IgE-mediated functions E Rönnberg, A Ghaib, C Ceriol, M Enoksson, M Arock, J Säfholm, M Ekoff, ... Frontiers in immunology 10, 1361, 2019 | 35 | 2019 |
| An optimized protocol for the isolation and functional analysis of human lung mast cells A Ravindran, E Rönnberg, JS Dahlin, L Mazzurana, J Säfholm, AC Orre, ... Frontiers in immunology 9, 2193, 2018 | 34 | 2018 |
| Dividing neutrophils in subsets reveals a significant role for activated neutrophils in the development of airway hyperreactivity S Ekstedt, J Säfholm, SK Georén, LO Cardell Clinical & Experimental Allergy 49 (3), 285-291, 2019 | 21 | 2019 |
| Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice J Säfholm, C Lövdahl, L Swedin, PJM Boels, SE Dahlén, A Arner, ... Pulmonary pharmacology & therapeutics 24 (4), 361-366, 2011 | 20 | 2011 |
| Budesonide prevents cytokine-induced decrease of the relaxant responses to formoterol and terbutaline, but not to salmeterol, in mouse trachea M Adner, B Larsson, J Säfholm, I Naya, A Miller-Larsson Journal of Pharmacology and Experimental Therapeutics 333 (1), 273-280, 2010 | 20 | 2010 |
| Immunoprofiling reveals novel mast cell receptors and the continuous nature of human lung mast cell heterogeneity E Rönnberg, DZH Boey, A Ravindran, J Säfholm, AC Orre, M Al-Ameri, ... Frontiers in Immunology 12, 804812, 2022 | 19 | 2022 |
| Mannitol triggers mast cell–dependent contractions of human small bronchi and prostacyclin bronchoprotection J Säfholm, ML Manson, J Bood, M Al-Ameri, AC Orre, J Raud, SE Dahlén, ... Journal of Allergy and Clinical Immunology 144 (4), 984-992, 2019 | 17 | 2019 |
| Antagonising EP1 and EP2 receptors reveal that the TP receptor mediates a component of antigen-induced contraction of the guinea pig trachea J Säfholm, SE Dahlén, M Adner European journal of pharmacology 718 (1-3), 277-282, 2013 | 15 | 2013 |
| Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction X Tang, E Rönnberg, J Säfholm, M Thulasingam, M Trauelsen, ... Allergy 77 (9), 2677-2687, 2022 | 10 | 2022 |
| Wnt-3a induces cytokine release in human mast cells J Tebroke, JE Lieverse, J Säfholm, G Schulte, G Nilsson, E Rönnberg Cells 8 (11), 1372, 2019 | 10 | 2019 |
| COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells AK Johnsson, E Rönnberg, D Fuchs, J Kolmert, J Säfholm, HE Claesson, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021 | 6 | 2021 |
| Complex involvement of interleukin-26 in bacterial lung infection KF Che, M Paulsson, K Piersiala, J Sax, I Mboob, M Rahman, RS Rekha, ... Frontiers in Immunology 12, 761317, 2021 | 5 | 2021 |
Martijn MansonAssistant Professor, Leiden Academic Centre for Drug Research (LACDR) / Master of Pharmacy LeidenVerified email at lacdr.leidenuniv.nl
