| Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ... Nature 596 (7872), 417-422, 2021 | 620 | 2021 |
| Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ... The American Journal of Human Genetics 100 (1), 75-90, 2017 | 408 | 2017 |
| Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine RP Payne, S Longet, JA Austin, DT Skelly, W Dejnirattisai, S Adele, ... Cell 184 (23), 5699-5714. e11, 2021 | 268 | 2021 |
| Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease L Bergamaschi, F Mescia, L Turner, AL Hanson, P Kotagiri, BJ Dunmore, ... Immunity 54 (6), 1257-1275. e8, 2021 | 265 | 2021 |
| The evolution of cellular deficiency in GATA2 mutation RE Dickinson, P Milne, L Jardine, S Zandi, SI Swierczek, N McGovern, ... Blood, The Journal of the American Society of Hematology 123 (6), 863-874, 2014 | 232 | 2014 |
| “A rose is a rose is a rose,” but CVID is not CVID: common variable immune deficiency (CVID), what do we know in 2011? PFK Yong, JED Thaventhiran, B Grimbacher Advances in immunology 111, 47-107, 2011 | 216 | 2011 |
| Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans P Tuijnenburg, HL Allen, SO Burns, D Greene, MH Jansen, E Staples, ... Journal of allergy and clinical immunology 142 (4), 1285-1296, 2018 | 209 | 2018 |
| Germline selection shapes human mitochondrial DNA diversity W Wei, S Tuna, MJ Keogh, KR Smith, TJ Aitman, PL Beales, DL Bennett, ... Science 364 (6442), eaau6520, 2019 | 184 | 2019 |
| CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response D Biasci, M Smoragiewicz, CM Connell, Z Wang, Y Gao, ... Proceedings of the National Academy of Sciences 117 (46), 28960-28970, 2020 | 173 | 2020 |
| Differential IRF8 transcription factor requirement defines two pathways of dendritic cell development in humans U Cytlak, A Resteu, S Pagan, K Green, P Milne, S Maisuria, D McDonald, ... Immunity 53 (2), 353-370. e8, 2020 | 170 | 2020 |
| Differential IRF8 transcription factor requirement defines two pathways of dendritic cell development in humans U Cytlak, A Resteu, S Pagan, K Green, P Milne, S Maisuria, D McDonald, ... Immunity 53 (2), 353-370. e8, 2020 | 170 | 2020 |
| Whole-genome sequencing of a sporadic primary immunodeficiency cohort JED Thaventhiran, H Lango Allen, OS Burren, W Rae, D Greene, ... Nature 583 (7814), 90-95, 2020 | 166 | 2020 |
| Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses S Spencer, S Köstel Bal, W Egner, H Lango Allen, SI Raza, CA Ma, ... Journal of Experimental Medicine 216 (9), 1986-1998, 2019 | 165 | 2019 |
| Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses S Spencer, S Köstel Bal, W Egner, H Lango Allen, SI Raza, CA Ma, ... Journal of Experimental Medicine 216 (9), 1986-1998, 2019 | 165 | 2019 |
| T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study A Angyal, S Longet, SC Moore, RP Payne, A Harding, T Tipton, ... The Lancet Microbe 3 (1), e21-e31, 2022 | 129 | 2022 |
| Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension C Hadinnapola, M Bleda, M Haimel, N Screaton, A Swift, P Dorfmüller, ... Circulation 136 (21), 2022-2033, 2017 | 126 | 2017 |
| Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report MS Buckland, JB Galloway, CN Fhogartaigh, L Meredith, NM Provine, ... Nature communications 11 (1), 6385, 2020 | 109 | 2020 |
| Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations T Lorenzini, M Fliegauf, N Klammer, N Frede, M Proietti, A Bulashevska, ... Journal of Allergy and Clinical Immunology 146 (4), 901-911, 2020 | 97 | 2020 |
| Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance Z Zhang, F Gothe, P Pennamen, JR James, D McDonald, CP Mata, ... Journal of Experimental Medicine 216 (6), 1311-1327, 2019 | 82 | 2019 |
| Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell JED Thaventhiran, A Hoffmann, L Magiera, M de la Roche, H Lingel, ... Proceedings of the National Academy of Sciences 109 (33), E2223-E2229, 2012 | 81 | 2012 |
