|Development of α-helical calpain probes by mimicking a natural protein–protein interaction|
H Jo, N Meinhardt, Y Wu, S Kulkarni, X Hu, KE Low, PL Davies, ...
Journal of the American Chemical Society 134 (42), 17704-17713, 2012
|The αvβ1 integrin plays a critical in vivo role in tissue fibrosis|
NI Reed, H Jo, C Chen, K Tsujino, TD Arnold, WF DeGrado, D Sheppard
Science translational medicine 7 (288), 288ra79-288ra79, 2015
|Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins|
AJ Reig, MM Pires, RA Snyder, Y Wu, H Jo, DW Kulp, SE Butch, ...
Nature chemistry 4 (11), 900-906, 2012
|Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus|
J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ...
Journal of medicinal chemistry 56 (7), 2804-2812, 2013
|Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding|
RM Culik, H Jo, WF DeGrado, F Gai
Journal of the American Chemical Society 134 (19), 8026-8029, 2012
|Asymmetric Total Synthesis of (+)-Brefeldin A from (S)-Lactate by Triple Chirality Transfer Process and Nitrile Oxide Cycloaddition,1|
D Kim, J Lee, PJ Shim, JI Lim, H Jo, S Kim
The Journal of organic chemistry 67 (3), 764-771, 2002
|Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 …|
Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ...
Journal of the American Chemical Society 136 (52), 17987-17995, 2014
|Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials|
MS Love, MG Millholland, S Mishra, S Kulkarni, KB Freeman, W Pan, ...
Cell host & microbe 12 (6), 815-823, 2012
|Highly stereoselective and efficient total synthesis of (+)-laurencin|
S Baek, H Jo, H Kim, H Kim, S Kim, D Kim
Organic letters 7 (1), 75-77, 2005
|Inhibition of integrin α2β1 ameliorates glomerular injury|
CM Borza, Y Su, X Chen, L Yu, S Mont, S Chetyrkin, P Voziyan, ...
Journal of the American Society of Nephrology 23 (6), 1027-1038, 2012
|Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment|
DT Moore, P Nygren, H Jo, K Boesze-Battaglia, JS Bennett, WF DeGrado
Proceedings of the National Academy of Sciences 109 (3), 793-798, 2012
|Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay|
E Lucumi, C Darling, H Jo, AD Napper, R Chandramohanadas, N Fisher, ...
Antimicrobial agents and chemotherapy 54 (9), 3597-3604, 2010
|Structural polymorphism of Alzheimer’s β-amyloid fibrils as controlled by an E22 switch: A solid-state NMR study|
MR Elkins, T Wang, M Nick, H Jo, T Lemmin, SB Prusiner, WF DeGrado, ...
Journal of the American Chemical Society 138 (31), 9840-9852, 2016
|Blue fluorescent amino acid for biological spectroscopy and microscopy|
MR Hilaire, IA Ahmed, CW Lin, H Jo, WF DeGrado, F Gai
Proceedings of the National Academy of Sciences 114 (23), 6005-6009, 2017
|Water distribution, dynamics, and interactions with Alzheimer’s β-amyloid fibrils investigated by solid-state NMR|
T Wang, H Jo, WF DeGrado, M Hong
Journal of the American Chemical Society 139 (17), 6242-6252, 2017
|Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation|
H Jo, RM Culik, IV Korendovych, WF DeGrado, F Gai
Biochemistry 49 (49), 10354-10356, 2010
|Pharmacologic blockade of αvβ1 integrin ameliorates renal failure and fibrosis in vivo|
Y Chang, WL Lau, H Jo, K Tsujino, L Gewin, NI Reed, A Atakilit, ...
Journal of the American Society of Nephrology 28 (7), 1998-2005, 2017
|Composite tether and methods for manufacturing, transporting, and installing same|
S Hanna, M Salama
US Patent App. 10/131,658, 2003
|Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of CaV Function|
F Findeisen, M Campiglio, H Jo, F Abderemane-Ali, CH Rumpf, L Pope, ...
ACS chemical neuroscience 8 (6), 1313-1326, 2017
|Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma|
A Sundaram, C Chen, A Khalifeh-Soltani, A Atakilit, X Ren, W Qiu, H Jo, ...
The Journal of clinical investigation 127 (1), 365-374, 2017