Pawel Kozielewicz
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The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
Mitochondrial protein biogenesis in the synapse is supported by local translation
B Kuzniewska, D Cysewski, M Wasilewski, P Sakowska, J Milek, ...
EMBO reports 21 (8), e48882, 2020
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
SC Wright, P Kozielewicz, M Kowalski-Jahn, J Petersen, CF Bowin, ...
Nature communications 10 (1), 667, 2019
Structural insight into small molecule action on Frizzleds
P Kozielewicz, A Turku, CF Bowin, J Petersen, J Valnohova, MCA Cañizal, ...
Nature communications 11 (1), 414, 2020
Antioxidant, cytotoxic, and antiproliferative activities and total polyphenol contents of the extracts of Geissospermum reticulatum bark
JJ Sajkowska-Kozielewicz, P Kozielewicz, NM Barnes, I Wawer, ...
Oxidative medicine and cellular longevity 2016, 2016
Molecular pharmacology of class F receptor activation
P Kozielewicz, A Turku, G Schulte
Molecular pharmacology 97 (2), 62-71, 2020
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled
J Wesslowski, P Kozielewicz, X Wang, H Cui, H Schihada, D Kranz, ...
Journal of Biological Chemistry 295 (26), 8759-8774, 2020
Structural insight into Class F receptors–What have we learnt regarding agonist‐induced activation?
G Schulte, P Kozielewicz
Basic & Clinical Pharmacology & Toxicology 126, 17-24, 2020
A NanoBRET-based binding assay for smoothened allows real-time analysis of ligand binding and distinction of two binding sites for BODIPY-cyclopamine
P Kozielewicz, CF Bowin, A Turku, G Schulte
Molecular Pharmacology 97 (1), 23-34, 2020
Novel vitamin D analogues; cytotoxic and anti-proliferative activity against a diffuse large B-cell lymphoma cell line and B-cells from healthy donors
P Kozielewicz, G Grafton, A Kutner, SJ Curnow, J Gordon, NM Barnes
The Journal of Steroid Biochemistry and Molecular Biology 164, 98-105, 2016
Insights into mechanism of anticancer activity of pentacyclic oxindole alkaloids of Uncaria tomentosa by means of a computational reverse virtual screening and …
P Kozielewicz, K Paradowska, S Erić, I Wawer, M Zloh
Monatshefte für Chemie-Chemical Monthly 145, 1201-1211, 2014
Intramolecular cyclization of β-nitroso-o-quinone methides. A theoretical endoscopy of a potentially useful innate ‘reclusive’reaction
D Tzeli, PG Tsoungas, ID Petsalakis, P Kozielewicz, M Zloh
Tetrahedron 71 (2), 359-369, 2015
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
L Xu, B Chen, H Schihada, SC Wright, A Turku, Y Wu, GW Han, ...
Cell Research 31 (12), 1311-1314, 2021
Residue 6.43 defines receptor function in class F GPCRs
A Turku, H Schihada, P Kozielewicz, CF Bowin, G Schulte
Nature communications 12 (1), 3919, 2021
Quantitative profiling of WNT-3A binding to all human Frizzled paralogues in HEK293 cells by nanoBiT/BRET assessments
P Kozielewicz, R Shekhani, S Moser, CF Bowin, J Wesslowski, ...
ACS Pharmacology & Translational Science 4 (3), 1235-1245, 2021
Naphthalene Peri Annelated N,N‐ and N,O‐Heterocycles: The Effect of Heteroatom‐Guided Peri‐Fusion on Their Structure and Reactivity Profiles‐A Theoretical …
D Tzeli, P Kozielewicz, M Zloh, D Antonow, PG Tsoungas, ID Petsalakis
ChemistrySelect 3 (33), 9743-9752, 2018
N‐glycosylation and expression in human tissues of the orphan GPR61 receptor
P Kozielewicz, H Alomar, S Yusof, G Grafton, AJ Cooper, SJ Curnow, ...
FEBS Open bio 7 (12), 1982-1993, 2017
2, 2′‐Dihydroxybenzophenones and Derivatives. Efficient Synthesis and Structure Endoscopy by DFT and NMR. Credentials as Potent Antiinflammatory Agents.
D Tzeli, P Kozielewicz, M Zervou, C Potamitis, K Kokkotou, B Rak, ...
ChemistrySelect 1 (10), 2426-2438, 2016
Overexpression of orphan receptor GPR61 increases cAMP levels upon Forskolin stimulation in HEK293 cells: in vitro and in silico validation of 5-(Nonyloxy) Tryptamine as a low …
P Kozielewicz, G Grafton, JJ Sajkowska-Kozielewicz, NM Barnes
Pharmacology 104 (5-6), 377-382, 2019
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