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Pawel Kozielewicz
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The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
7422019
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
4452021
Mitochondrial protein biogenesis in the synapse is supported by local translation
B Kuzniewska, D Cysewski, M Wasilewski, P Sakowska, J Milek, ...
EMBO reports 21 (8), e48882, 2020
732020
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
SC Wright, P Kozielewicz, M Kowalski-Jahn, J Petersen, CF Bowin, ...
Nature communications 10 (1), 667, 2019
652019
Structural insight into small molecule action on Frizzleds
P Kozielewicz, A Turku, CF Bowin, J Petersen, J Valnohova, MCA Cañizal, ...
Nature communications 11 (1), 414, 2020
462020
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, AA Mathie, ...
British journal of pharmacology 180, S23-S144, 2023
332023
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled
J Wesslowski, P Kozielewicz, X Wang, H Cui, H Schihada, D Kranz, ...
Journal of Biological Chemistry 295 (26), 8759-8774, 2020
332020
Molecular pharmacology of class F receptor activation
P Kozielewicz, A Turku, G Schulte
Molecular pharmacology 97 (2), 62-71, 2020
312020
Antioxidant, cytotoxic, and antiproliferative activities and total polyphenol contents of the extracts of Geissospermum reticulatum bark
JJ Sajkowska-Kozielewicz, P Kozielewicz, NM Barnes, I Wawer, ...
Oxidative medicine and cellular longevity 2016, 2016
292016
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
L Xu, B Chen, H Schihada, SC Wright, A Turku, Y Wu, GW Han, ...
Cell research 31 (12), 1311-1314, 2021
262021
Structural insight into Class F receptors–What have we learnt regarding agonist‐induced activation?
G Schulte, P Kozielewicz
Basic & Clinical Pharmacology & Toxicology 126, 17-24, 2020
262020
A NanoBRET-based binding assay for smoothened allows real-time analysis of ligand binding and distinction of two binding sites for BODIPY-cyclopamine
P Kozielewicz, CF Bowin, A Turku, G Schulte
Molecular pharmacology 97 (1), 23-34, 2020
222020
Quantitative profiling of WNT-3A binding to all human frizzled paralogues in HEK293 cells by NanoBiT/BRET assessments
P Kozielewicz, R Shekhani, S Moser, CF Bowin, J Wesslowski, ...
ACS Pharmacology & Translational Science 4 (3), 1235-1245, 2021
182021
Intramolecular cyclization of β-nitroso-o-quinone methides. A theoretical endoscopy of a potentially useful innate ‘reclusive’reaction
D Tzeli, PG Tsoungas, ID Petsalakis, P Kozielewicz, M Zloh
Tetrahedron 71 (2), 359-369, 2015
182015
Novel vitamin D analogues; cytotoxic and anti-proliferative activity against a diffuse large B-cell lymphoma cell line and B-cells from healthy donors
P Kozielewicz, G Grafton, A Kutner, SJ Curnow, J Gordon, NM Barnes
The Journal of Steroid Biochemistry and Molecular Biology 164, 98-105, 2016
172016
Residue 6.43 defines receptor function in class F GPCRs
A Turku, H Schihada, P Kozielewicz, CF Bowin, G Schulte
Nature Communications 12 (1), 3919, 2021
162021
Insights into mechanism of anticancer activity of pentacyclic oxindole alkaloids of Uncaria tomentosa by means of a computational reverse virtual screening and …
P Kozielewicz, K Paradowska, S Erić, I Wawer, M Zloh
Monatshefte für Chemie-Chemical Monthly 145, 1201-1211, 2014
162014
Naphthalene Peri Annelated N,N‐ and N,O‐Heterocycles: The Effect of Heteroatom‐Guided Peri‐Fusion on Their Structure and Reactivity Profiles‐A Theoretical …
D Tzeli, P Kozielewicz, M Zloh, D Antonow, PG Tsoungas, ID Petsalakis
ChemistrySelect 3 (33), 9743-9752, 2018
102018
N‐glycosylation and expression in human tissues of the orphan GPR61 receptor
P Kozielewicz, H Alomar, S Yusof, G Grafton, AJ Cooper, SJ Curnow, ...
FEBS Open bio 7 (12), 1982-1993, 2017
102017
WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction
CF Bowin, P Kozielewicz, L Grätz, M Kowalski-Jahn, H Schihada, ...
Science Signaling 16 (779), eabo4974, 2023
92023
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