Konrad Scheffler
Konrad Scheffler
Verifierad e-postadress på illumina.com
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Detecting individual sites subject to episodic diversifying selection
B Murrell, JO Wertheim, S Moola, T Weighill, K Scheffler, ...
PLoS genetics 8 (7), e1002764, 2012
11182012
FUBAR: a fast, unconstrained bayesian approximation for inferring selection
B Murrell, S Moola, A Mabona, T Weighill, D Sheward, ...
Molecular biology and evolution 30 (5), 1196-1205, 2013
7612013
A random effects branch-site model for detecting episodic diversifying selection
SL Kosakovsky Pond, B Murrell, M Fourment, SDW Frost, W Delport, ...
Molecular biology and evolution 28 (11), 3033-3043, 2011
4222011
Strelka2: fast and accurate calling of germline and somatic variants
S Kim, K Scheffler, AL Halpern, MA Bekritsky, E Noh, M Källberg, X Chen, ...
Nature methods 15 (8), 591-594, 2018
3912018
Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection
MD Smith, JO Wertheim, S Weaver, B Murrell, K Scheffler, ...
Molecular biology and evolution 32 (5), 1342-1353, 2015
3242015
Gene-wide identification of episodic selection
B Murrell, S Weaver, MD Smith, JO Wertheim, S Murrell, A Aylward, ...
Molecular biology and evolution 32 (5), 1365-1371, 2015
2722015
RELAX: detecting relaxed selection in a phylogenetic framework
JO Wertheim, B Murrell, MD Smith, SL Kosakovsky Pond, K Scheffler
Molecular biology and evolution 32 (3), 820-832, 2015
2332015
Robust inference of positive selection from recombining coding sequences
K Scheffler, DP Martin, C Seoighe
Bioinformatics 22 (20), 2493-2499, 2006
2122006
Automatic learning of dialogue strategy using dialogue simulation and reinforcement learning
K Scheffler, S Young
Proceedings of HLT 2, 2002
1852002
Evolutionary origins of human herpes simplex viruses 1 and 2
JO Wertheim, MD Smith, DM Smith, K Scheffler, SL Kosakovsky Pond
Molecular biology and evolution 31 (9), 2356-2364, 2014
1312014
Corpus-based dialogue simulation for automatic strategy learning and evaluation
K Scheffler, S Young
Proc. NAACL Workshop on Adaptation in Dialogue Systems, 64-70, 2001
1192001
Social and genetic networks of HIV-1 transmission in New York City
JO Wertheim, SL Kosakovsky Pond, LA Forgione, SR Mehta, B Murrell, ...
PLoS pathogens 13 (1), e1006000, 2017
1132017
Models of coding sequence evolution
W Delport, K Scheffler, C Seoighe
Briefings in bioinformatics 10 (1), 97-109, 2009
862009
CodonTest: modeling amino acid substitution preferences in coding sequences
W Delport, K Scheffler, G Botha, MB Gravenor, SV Muse, ...
PLoS computational biology 6 (8), e1000885, 2010
792010
Evolutionary fingerprinting of genes
SL Kosakovsky Pond, K Scheffler, MB Gravenor, AFY Poon, SDW Frost
Molecular biology and evolution 27 (3), 520-536, 2010
682010
Deep sequencing reveals minor protease resistance mutations in patients failing a protease inhibitor regimen
R Fisher, GU van Zyl, SAA Travers, SL Kosakovsky Pond, S Engelbrech, ...
Journal of virology 86 (11), 6231-6237, 2012
592012
Frequent toggling between alternative amino acids is driven by selection in HIV-1
W Delport, K Scheffler, C Seoighe
PLoS pathogens 4 (12), e1000242, 2008
582008
Probabilistic simulation of human-machine dialogues
K Scheffler, S Young
2000 IEEE International Conference on Acoustics, Speech, and Signal …, 2000
582000
Correcting the bias of empirical frequency parameter estimators in codon models
S Kosakovsky Pond, W Delport, SV Muse, K Scheffler
PloS one 5 (7), e11230, 2010
522010
Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial
PT Edlefsen, M Rolland, T Hertz, S Tovanabutra, AJ Gartland, ...
PLoS computational biology 11 (2), e1003973, 2015
492015
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Artiklar 1–20