| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013 | 6537 | 2013 |
| Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2 J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ... New England Journal of Medicine 369 (25), 2391-2405, 2013 | 1635 | 2013 |
| The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012 | 1614 | 2012 |
| Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 1506 | 2012 |
| Clinical and biological implications of driver mutations in myelodysplastic syndromes E Papaemmanuil, M Gerstung, L Malcovati, S Tauro, G Gundem, ... Blood 122 (22), 3616-3627, 2013 | 1365 | 2013 |
| Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 1304 | 2016 |
| The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1227 | 2012 |
| High burden and pervasive positive selection of somatic mutations in normal human skin I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ... Science 348 (6237), 880-886, 2015 | 1021 | 2015 |
| The evolutionary history of lethal metastatic prostate cancer G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ... Nature 520 (7547), 353-357, 2015 | 950 | 2015 |
| Spatial and temporal diversity in genomic instability processes defines lung cancer evolution EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ... Science 346 (6206), 251-256, 2014 | 896 | 2014 |
| Deciphering signatures of mutational processes operative in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton Cell reports 3 (1), 246-259, 2013 | 838 | 2013 |
| Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing J Zhang, J Fujimoto, J Zhang, DC Wedge, X Song, J Zhang, S Seth, ... Science 346 (6206), 256-259, 2014 | 753 | 2014 |
| Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature communications 5 (1), 1-13, 2014 | 692 | 2014 |
| Clock-like mutational processes in human somatic cells LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ... Nature genetics 47 (12), 1402, 2015 | 574 | 2015 |
| Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature medicine 21 (7), 751, 2015 | 569 | 2015 |
| Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ... Nature genetics 45 (12), 1479-1482, 2013 | 490 | 2013 |
| Effect of mutation order on myeloproliferative neoplasms CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ... New England Journal of Medicine 372 (7), 601-612, 2015 | 412 | 2015 |
| Genomic evolution of breast cancer metastasis and relapse LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ... Cancer cell 32 (2), 169-184. e7, 2017 | 353 | 2017 |
| Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ... Nature genetics 47 (4), 367-372, 2015 | 350 | 2015 |
| RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia E Papaemmanuil, I Rapado, Y Li, NE Potter, DC Wedge, J Tubio, ... Nature genetics 46 (2), 116-125, 2014 | 299 | 2014 |
Ludmil B. AlexandrovAssistant Professor, University of California San DiegoVerified email at ucsd.edu
