| Rational optimization of conformational effects induced by hydrocarbon staples in peptides and their binding interfaces D Lama, ST Quah, CS Verma, R Lakshminarayanan, RW Beuerman, ... Scientific reports 3 (1), 3451, 2013 | 74 | 2013 |
| Anti‐apoptotic Bcl‐XL protein in complex with BH3 peptides of pro‐apoptotic Bak, Bad, and Bim proteins: Comparative molecular dynamics simulations D Lama, R Sankararamakrishnan Proteins: Structure, Function, and Bioinformatics 73 (2), 492-514, 2008 | 70 | 2008 |
| c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression WJ Sim, PV Iyengar, D Lama, SKL Lui, HC Ng, L Haviv-Shapira, ... Nature communications 10 (1), 4349, 2019 | 59 | 2019 |
| USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination PV Iyengar, P Jaynes, L Rodon, D Lama, KP Law, YP Lim, C Verma, ... Scientific reports 5 (1), 14733, 2015 | 53 | 2015 |
| Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic … D Lama, R Sankararamakrishnan Journal of Computer-Aided Molecular Design 25, 413-426, 2011 | 36 | 2011 |
| R248Q mutation—Beyond p53‐DNA binding JWK Ng, D Lama, S Lukman, DP Lane, CS Verma, AYL Sim Proteins: Structure, Function, and Bioinformatics 83 (12), 2240-2250, 2015 | 32 | 2015 |
| Identification of core structural residues in the sequentially diverse and structurally homologous Bcl-2 family of proteins D Lama, R Sankararamakrishnan Biochemistry 49 (11), 2574-2584, 2010 | 30 | 2010 |
| Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein D Lama, AM Liberatore, Y Frosi, J Nakhle, N Tsomaia, T Bashir, DP Lane, ... Chemical Science 10 (8), 2489-2500, 2019 | 22 | 2019 |
| Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent V Modi, D Lama, R Sankararamakrishnan Journal of Biomolecular Structure and Dynamics 31 (1), 65-77, 2013 | 19 | 2013 |
| Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase XY Koh, XH Koh, L Hwang, FJ Ferrer, SAB Rahmat, D Lama, DP Lane Oncogene 38 (48), 7342-7356, 2019 | 15 | 2019 |
| Gating by tryptophan 73 exposes a cryptic pocket at the Protein-Binding interface of the oncogenic eIF4E protein D Lama, CJ Brown, DP Lane, CS Verma Biochemistry 54 (42), 6535-6544, 2015 | 15 | 2015 |
| Behavior of Solvent-Exposed Hydrophobic Groove in the Anti-Apoptotic Bcl-XL Protein: Clues for Its Ability to Bind Diverse BH3 Ligands from MD Simulations D Lama, V Modi, R Sankararamakrishnan Plos one 8 (2), e54397, 2013 | 15 | 2013 |
| Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition D Lama, CS Verma Protein Science 29 (6), 1373-1386, 2020 | 14 | 2020 |
| Water-bridge mediates recognition of mRNA cap in eIF4E D Lama, MR Pradhan, CJ Brown, RS Eapen, TL Joseph, CK Kwoh, ... Structure 25 (1), 188-194, 2017 | 14 | 2017 |
| Evidence of a conserved intrinsically disordered region in the C-terminus of the stringent response protein Rel from mycobacteria L Ekal, B Ganesh, H Joshi, D Lama, V Jain FEBS letters 588 (9), 1839-1849, 2014 | 10 | 2014 |
| Mass spectrometry of RNA-binding proteins during liquid–liquid phase separation reveals distinct assembly mechanisms and droplet architectures C Sahin, A Motso, X Gu, H Feyrer, D Lama, T Arndt, A Rising, GV Gese, ... Journal of the American Chemical Society 145 (19), 10659-10668, 2023 | 9 | 2023 |
| TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signaling PV Iyengar, DL Marvin, D Lama, TZ Tan, S Suriyamurthy, F Xie, ... Molecular Cancer Research 20 (10), 1516-1531, 2022 | 9 | 2022 |
| Liquid–liquid phase separation primes spider silk proteins for fiber formation via a conditional sticker domain A Leppert, G Chen, D Lama, C Sahin, V Railaite, O Shilkova, T Arndt, ... Nano Letters 23 (12), 5836-5841, 2023 | 8 | 2023 |
| Homologous Lympho-Epithelial Kazal-type inhibitor domains delay blood coagulation by inhibiting factor X and XI with differential specificity K Ramesh, D Lama, KW Tan, FT Chew, CS Verma, YK Mok Structure 26 (9), 1178-1186. e3, 2018 | 7 | 2018 |
| Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex Y Frosi, YC Lin, J Shimin, SR Ramlan, K Hew, AH Engman, A Pillai, ... Nature communications 13 (1), 4854, 2022 | 6 | 2022 |
Chandra VermaBioinformatics InstituteVerifierad e-postadress på bii.a-star.edu.sg
