| Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth H Zhang, DZ Qian, YS Tan, KA Lee, P Gao, YR Ren, S Rey, H Hammers, ... Proceedings of the National Academy of Sciences 105 (50), 19579-19586, 2008 | 716 | 2008 |
| Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization KA Lee, H Zhang, DZ Qian, S Rey, JO Liu, GL Semenza Proceedings of the National Academy of Sciences 106 (42), 17910-17915, 2009 | 561 | 2009 |
| Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer ML Zhu, CM Horbinski, M Garzotto, DZ Qian, TM Beer, N Kyprianou Cancer research 70 (20), 7992-8002, 2010 | 417 | 2010 |
| Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1α DZ Qian, SK Kachhap, SJ Collis, HMW Verheul, MA Carducci, P Atadja, ... Cancer research 66 (17), 8814-8821, 2006 | 373 | 2006 |
| Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells KA Lee, DZ Qian, S Rey, H Wei, JO Liu, GL Semenza Proceedings of the National Academy of Sciences 106 (7), 2353-2358, 2009 | 352 | 2009 |
| Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589 DZ Qian, Y Kato, S Shabbeer, Y Wei, HMW Verheul, B Salumbides, ... Clinical Cancer Research 12 (2), 634-642, 2006 | 320 | 2006 |
| The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor … DZ Qian, X Wang, SK Kachhap, Y Kato, Y Wei, L Zhang, P Atadja, R Pili Cancer research 64 (18), 6626-6634, 2004 | 279 | 2004 |
| Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: therapy with sequential 1-β-D-arabinofuranosylcytosine, mitoxantrone … JE Karp, I Gojo, R Pili, CD Gocke, J Greer, C Guo, D Qian, L Morris, ... Clinical Cancer Research 10 (11), 3577-3585, 2004 | 254 | 2004 |
| HDAC4 protein regulates HIF1α protein lysine acetylation and cancer cell response to hypoxia H Geng, CT Harvey, J Pittsenbarger, Q Liu, TM Beer, C Xue, DZ Qian Journal of Biological Chemistry 286 (44), 38095-38102, 2011 | 227 | 2011 |
| Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours R Pili, B Salumbides, M Zhao, S Altiok, D Qian, J Zwiebel, MA Carducci, ... British journal of cancer 106 (1), 77-84, 2012 | 177 | 2012 |
| HIF1α protein stability is increased by acetylation at lysine 709 H Geng, Q Liu, C Xue, LL David, TM Beer, GV Thomas, MS Dai, DZ Qian Journal of Biological Chemistry 287 (42), 35496-35505, 2012 | 176 | 2012 |
| Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data D Sun, X Guan, AE Moran, LY Wu, DZ Qian, P Schedin, MS Dai, ... Nature biotechnology 40 (4), 527-538, 2022 | 154 | 2022 |
| Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model HMW Verheul, H Hammers, K Van Erp, Y Wei, T Sanni, B Salumbides, ... Clinical Cancer Research 13 (14), 4201-4208, 2007 | 146 | 2007 |
| CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel‐induced cytotoxicity DZ Qian, BLS Rademacher, J Pittsenbarger, CY Huang, A Myrthue, ... The Prostate 70 (4), 433-442, 2010 | 143 | 2010 |
| The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin SK Kachhap, D Faith, DZ Qian, S Shabbeer, NL Galloway, R Pili, ... PloS one 2 (9), e844, 2007 | 140 | 2007 |
| Identification of a potent inhibitor of CREB-mediated gene transcription with efficacious in vivo anticancer activity F Xie, BX Li, A Kassenbrock, C Xue, X Wang, DZ Qian, RC Sears, X Xiao Journal of medicinal chemistry 58 (12), 5075-5087, 2015 | 139 | 2015 |
| Platelets take up the monoclonal antibody bevacizumab HMW Verheul, MPJ Lolkema, DZ Qian, YHA Hilkes, E Liapi, ... Clinical cancer research 13 (18), 5341-5347, 2007 | 130 | 2007 |
| Combination strategy targeting the hypoxia inducible factor-1α with mammalian target of rapamycin and histone deacetylase inhibitors HMW Verheul, B Salumbides, K Van Erp, H Hammers, DZ Qian, T Sanni, ... Clinical cancer research 14 (11), 3589-3597, 2008 | 119 | 2008 |
| Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target CR Chong, DZ Qian, F Pan, Y Wei, R Pili, DJ Sullivan, JO Liu Journal of medicinal chemistry 49 (9), 2677-2680, 2006 | 113 | 2006 |
| Identification of ABR‐215050 as lead second generation quinoline‐3‐carboxamide anti‐angiogenic agent for the treatment of prostate cancer JT Isaacs, R Pili, DZ Qian, SL Dalrymple, JB Garrison, N Kyprianou, ... The Prostate 66 (16), 1768-1778, 2006 | 110 | 2006 |
