| Preclinical characterization of 18F-MK-6240, a promising PET tracer for in vivo quantification of human neurofibrillary tangles ED Hostetler, AM Walji, Z Zeng, P Miller, I Bennacef, C Salinas, ... Journal of nuclear medicine 57 (10), 1599-1606, 2016 | 245 | 2016 |
| Discovery of 6-(Fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for … AM Walji, ED Hostetler, H Selnick, Z Zeng, P Miller, I Bennacef, C Salinas, ... Journal of medicinal chemistry 59 (10), 4778-4789, 2016 | 169 | 2016 |
| In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C … ED Hostetler, AD Joshi, S Sanabria-Bohórquez, H Fan, Z Zeng, M Purcell, ... Journal of Pharmacology and Experimental Therapeutics 347 (2), 478-486, 2013 | 132 | 2013 |
| Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans M Doss, HC Kolb, JJ Zhang, MJ Bélanger, JB Stubbs, MG Stabin, ... Journal of Nuclear Medicine 53 (5), 787-795, 2012 | 109 | 2012 |
| Brain imaging of Alzheimer dementia patients and elderly controls with 18F-MK-6240, a PET tracer targeting neurofibrillary tangles TG Lohith, I Bennacef, R Vandenberghe, M Vandenbulcke, CA Salinas, ... Journal of Nuclear Medicine 60 (1), 107-114, 2019 | 101 | 2019 |
| In vivo imaging of the programmed death ligand 1 by 18F PET DEG Trotter, X Meng, P McQuade, D Rubins, M Klimas, Z Zeng, ... Journal of Nuclear Medicine 58 (11), 1852-1857, 2017 | 100 | 2017 |
| In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1, 2, 4-triazol-5-ylmethoxy)-pyrazolo [1, 5-d]-[1, 2, 4] triazine (MRK-016), a GABAA … JR Atack, KA Maubach, KA Wafford, D O'Connor, AD Rodrigues, ... Journal of Pharmacology and Experimental Therapeutics 331 (2), 470-484, 2009 | 89 | 2009 |
| Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery RW Pipal, KT Stout, PZ Musacchio, S Ren, TJA Graham, S Verhoog, ... Nature 589 (7843), 542-547, 2021 | 70 | 2021 |
| The role of MRI and PET/SPECT in Alzheimer's disease A Coimbra, DS Williams, ED Hostetler Current topics in medicinal chemistry 6 (6), 629-647, 2006 | 67 | 2006 |
| Biodistribution and radiation dosimetry of the hypoxia marker 18F–HX4 in monkeys and humans determined by using whole-body PET/CT M Doss, JJ Zhang, MJ Bélanger, JB Stubbs, ED Hostetler, K Alpaugh, ... Nuclear medicine communications 31 (12), 1016-1024, 2010 | 66 | 2010 |
| Synthesis of 2-[18F] fluoroestradiol, a potential diagnostic imaging agent for breast cancer: Strategies to achieve nucleophilic substitution of an electron-rich aromatic ring … ED Hostetler, SD Jonson, MJ Welch, JA Katzenellenbogen The Journal of Organic Chemistry 64 (1), 178-185, 1999 | 65 | 1999 |
| A remote-controlled high pressure reactor for radiotracer synthesis with [11C] carbon monoxide ED Hostetler, HD Burns Nuclear medicine and biology 29 (8), 845-848, 2002 | 63 | 2002 |
| Characterization of ubrogepant: a potent and selective antagonist of the human calcitonin gene‒related peptide receptor E Moore, ME Fraley, IM Bell, CS Burgey, RB White, CC Li, CP Regan, ... Journal of Pharmacology and Experimental Therapeutics 373 (1), 160-166, 2020 | 59 | 2020 |
| MK-8719, a novel and selective O-GlcNAcase inhibitor that reduces the formation of pathological tau and ameliorates neurodegeneration in a mouse model of tauopathy X Wang, W Li, J Marcus, M Pearson, L Song, K Smith, G Terracina, J Lee, ... Journal of Pharmacology and Experimental Therapeutics 374 (2), 252-263, 2020 | 56 | 2020 |
| Synthesis, characterization, and monkey PET studies of [18F]MK‐1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK‐5435 ED Hostetler, W Eng, AD Joshi, S Sanabria‐Bohórquez, H Kawamoto, ... Synapse 65 (2), 125-135, 2011 | 56 | 2011 |
| Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist BM Connolly, A Vanko, P McQuade, I Guenther, X Meng, D Rubins, ... Molecular Imaging and Biology 14, 79-87, 2012 | 55 | 2012 |
| An improved synthesis of substituted [11C]toluenes via Suzuki coupling with [11C]methyl iodide ED Hostetler, GE Terry, H Donald Burns Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2005 | 51 | 2005 |
| Improved Methods for the Synthesis of [ω-11C]Palmitic Acid ED Hostetler, S Fallis, TJ McCarthy, MJ Welch, JA Katzenellenbogen The Journal of Organic Chemistry 63 (4), 1348-1351, 1998 | 51 | 1998 |
| An improved synthesis of substituted [11C]toluenes via Suzuki coupling with [11C]methyl iodide ED Hostetler, GE Terry, H Donald Burns Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2005 | 46 | 2005 |
| Synthesis, characterization, and monkey positron emission tomography (PET) studies of [18F] Y1-973, a PET tracer for the neuropeptide Y Y1 receptor ED Hostetler, S Sanabria-Bohórquez, H Fan, Z Zeng, L Gantert, ... Neuroimage 54 (4), 2635-2642, 2011 | 41 | 2011 |
