André Mateus
André Mateus
Assistant Professor at Umeå University | Team Leader at Molecular Infection Medicine Sweden (MIMS)
Verified email at - Homepage
Cited by
Cited by
A new antibiotic selectively kills Gram-negative pathogens
Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ...
Nature 576 (7787), 459-464, 2019
Species-specific activity of antibacterial drug combinations
AR Brochado, A Telzerow, J Bobonis, M Banzhaf, A Mateus, J Selkrig, ...
Nature 559 (7713), 259-263, 2018
The functional landscape of the human phosphoproteome
D Ochoa, AF Jarnuczak, C Viéitez, M Gehre, M Soucheray, A Mateus, ...
Nature biotechnology 38 (3), 365-373, 2020
A dual-mechanism antibiotic kills gram-negative bacteria and avoids drug resistance
JK Martin, JP Sheehan, BP Bratton, GM Moore, A Mateus, SHJ Li, H Kim, ...
Cell 181 (7), 1518-1532. e14, 2020
Pervasive protein thermal stability variation during the cell cycle
I Becher, A Andrés-Pons, N Romanov, F Stein, M Schramm, F Baudin, ...
Cell 173 (6), 1495-1507. e18, 2018
Bioaccumulation of therapeutic drugs by human gut bacteria
M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ...
Nature 597 (7877), 533-538, 2021
Rapid measurement of intracellular unbound drug concentrations
A Mateus, P Matsson, P Artursson
Molecular pharmaceutics 10 (6), 2467-2478, 2013
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
H Almqvist, H Axelsson, R Jafari, C Dan, A Mateus, M Haraldsson, ...
Nature communications 7 (1), 11040, 2016
Thermal proteome profiling for interrogating protein interactions
A Mateus, N Kurzawa, I Becher, S Sridharan, D Helm, F Stein, A Typas, ...
Molecular systems biology 16 (3), e9232, 2020
Thermal proteome profiling in bacteria: probing protein state in vivo
A Mateus, J Bobonis, N Kurzawa, F Stein, D Helm, J Hevler, A Typas, ...
Molecular systems biology 14 (7), e8242, 2018
Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes
A Mateus, TA Määttä, MM Savitski
Proteome science 15 (1), 1-7, 2016
Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli
M Banzhaf, HCL Yau, J Verheul, A Lodge, G Kritikos, A Mateus, B Cordier, ...
The EMBO journal 39 (5), e102246, 2020
Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery
A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ...
Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017
Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems
J Bobonis, K Mitosch, A Mateus, N Karcher, G Kritikos, J Selkrig, M Zietek, ...
Nature 609 (7925), 144-150, 2022
Intracellular drug bioavailability: a new predictor of system dependent drug disposition
A Mateus, A Treyer, C Wegler, M Karlgren, P Matsson, P Artursson
Scientific reports 7 (1), 43047, 2017
Impact of phosphorylation on thermal stability of proteins
CM Potel, N Kurzawa, I Becher, A Typas, A Mateus, MM Savitski
Nature methods 18 (7), 757-759, 2021
Direct measurement of intracellular compound concentration by rapidfire mass spectrometry offers insights into cell permeability
LJ Gordon, M Allen, PER Artursson, MM Hann, BJ Leavens, A Mateus, ...
Journal of biomolecular screening 21 (2), 156-164, 2016
The functional proteome landscape of Escherichia coli
A Mateus, J Hevler, J Bobonis, N Kurzawa, M Shah, K Mitosch, ...
Nature 588 (7838), 473-478, 2020
Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients
J Goncalves-Pereira, NE Silva, A Mateus, C Pinho, P Povoa
BMC Pharmacology and Toxicology 15 (1), 1-7, 2014
Mechanistic modeling of pitavastatin disposition in sandwich-cultured human hepatocytes: a proteomics-informed bottom-up approach
A Vildhede, A Mateus, EK Khan, Y Lai, M Karlgren, P Artursson, ...
Drug Metabolism and Disposition 44 (4), 505-516, 2016
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