| A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019 | 378 | 2019 |
| Species-specific activity of antibacterial drug combinations AR Brochado, A Telzerow, J Bobonis, M Banzhaf, A Mateus, J Selkrig, ... Nature 559 (7713), 259-263, 2018 | 235 | 2018 |
| The functional landscape of the human phosphoproteome D Ochoa, AF Jarnuczak, C Viéitez, M Gehre, M Soucheray, A Mateus, ... Nature biotechnology 38 (3), 365-373, 2020 | 221 | 2020 |
| Pervasive protein thermal stability variation during the cell cycle I Becher, A Andrés-Pons, N Romanov, F Stein, M Schramm, F Baudin, ... Cell 173 (6), 1495-1507. e18, 2018 | 166 | 2018 |
| A dual-mechanism antibiotic kills gram-negative bacteria and avoids drug resistance JK Martin II, JP Sheehan, BP Bratton, GM Moore, A Mateus, SHJ Li, H Kim, ... Cell 181 (7), 1518-1532. e14, 2020 | 145 | 2020 |
| Rapid measurement of intracellular unbound drug concentrations A Mateus, P Matsson, P Artursson Molecular pharmaceutics 10 (6), 2467-2478, 2013 | 143 | 2013 |
| CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil H Almqvist, H Axelsson, R Jafari, C Dan, A Mateus, M Haraldsson, ... Nature communications 7 (1), 11040, 2016 | 133 | 2016 |
| Thermal proteome profiling in bacteria: probing protein state in vivo A Mateus, J Bobonis, N Kurzawa, F Stein, D Helm, J Hevler, A Typas, ... Molecular systems biology 14 (7), e8242, 2018 | 126 | 2018 |
| Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes A Mateus, TA Määttä, MM Savitski Proteome science 15 (1), 1-7, 2016 | 117 | 2016 |
| Thermal proteome profiling for interrogating protein interactions A Mateus, N Kurzawa, I Becher, S Sridharan, D Helm, F Stein, A Typas, ... Molecular systems biology 16 (3), e9232, 2020 | 107 | 2020 |
| Bioaccumulation of therapeutic drugs by human gut bacteria M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ... Nature 597 (7877), 533-538, 2021 | 102 | 2021 |
| Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ... Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017 | 77 | 2017 |
| Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli M Banzhaf, HCL Yau, J Verheul, A Lodge, G Kritikos, A Mateus, B Cordier, ... The EMBO journal 39 (5), e102246, 2020 | 65* | 2020 |
| Intracellular drug bioavailability: a new predictor of system dependent drug disposition A Mateus, A Treyer, C Wegler, M Karlgren, P Matsson, P Artursson Scientific reports 7 (1), 43047, 2017 | 65 | 2017 |
| Direct measurement of intracellular compound concentration by rapidfire mass spectrometry offers insights into cell permeability LJ Gordon, M Allen, PER Artursson, MM Hann, BJ Leavens, A Mateus, ... Journal of biomolecular screening 21 (2), 156-164, 2016 | 60 | 2016 |
| Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients J Goncalves-Pereira, NE Silva, A Mateus, C Pinho, P Povoa BMC Pharmacology and Toxicology 15 (1), 1-7, 2014 | 54 | 2014 |
| Impact of phosphorylation on thermal stability of proteins CM Potel, N Kurzawa, I Becher, A Typas, A Mateus, MM Savitski Nature methods 18 (7), 757-759, 2021 | 52 | 2021 |
| Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems J Bobonis, K Mitosch, A Mateus, N Karcher, G Kritikos, J Selkrig, M Zietek, ... Nature 609 (7925), 144-150, 2022 | 47* | 2022 |
| Mechanistic modeling of pitavastatin disposition in sandwich-cultured human hepatocytes: a proteomics-informed bottom-up approach A Vildhede, A Mateus, EK Khan, Y Lai, M Karlgren, P Artursson, ... Drug Metabolism and Disposition 44 (4), 505-516, 2016 | 47 | 2016 |
| The functional proteome landscape of Escherichia coli A Mateus, J Hevler, J Bobonis, N Kurzawa, M Shah, K Mitosch, ... Nature 588 (7838), 473-478, 2020 | 38 | 2020 |
Mikhail SavitskiEMBLVerified email at embl.de
