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Victoria von Saucken
Victoria von Saucken
Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program
Verifierad e-postadress på med.cornell.edu
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TREM2 in neurodegenerative diseases
TR Jay, VE von Saucken, GE Landreth
Molecular neurodegeneration 12 (1), 1-33, 2017
3512017
Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
U Dettmer, AJ Newman, F Soldner, ES Luth, NC Kim, VE Von Saucken, ...
Nature communications 6 (1), 1-16, 2015
3302015
The T rem 2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease
PJ Cheng-Hathaway, EG Reed-Geaghan, TR Jay, BT Casali, SM Bemiller, ...
Molecular neurodegeneration 13 (1), 1-12, 2018
1942018
KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity
U Dettmer, AJ Newman, VE von Saucken, T Bartels, D Selkoe
Proceedings of the National Academy of Sciences 112 (31), 9596-9601, 2015
1772015
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells
U Dettmer, N Ramalingam, VE von Saucken, TE Kim, AJ Newman, ...
Human molecular genetics 26 (18), 3466-3481, 2017
832017
TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment
TR Jay, VE von Saucken, B Muñoz, JF Codocedo, BK Atwood, BT Lamb, ...
Glia 67 (10), 1873-1892, 2019
712019
Corrigendum: Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
U Dettmer, AJ Newman, F Soldner, ES Luth, NC Kim, VE Von Saucken, ...
Nature communications 6, 2015
202015
The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease
VE von Saucken, TR Jay, GE Landreth
Neurobiology of disease 145, 105072, 2020
152020
Crowded organelles, lipid accumulation, and abnormal membrane tubulation in cellular models of enhanced α-synuclein membrane interaction
M Ericsson, V von Saucken, AJ Newman, L Doehr, C Hoesch, TE Kim, ...
Brain Research 1758, 147349, 2021
112021
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Artiklar 1–9