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Matthew A. Cooper
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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muņoz-Planillo, ...
Nature medicine 21 (3), 248-255, 2015
22552015
Optical biosensors in drug discovery
MA Cooper
Nature reviews Drug discovery 1 (7), 515-528, 2002
13952002
Emerging pathogenic links between microbiota and the gut–lung axis
KF Budden, SL Gellatly, DLA Wood, MA Cooper, M Morrison, ...
Nature Reviews Microbiology 15 (1), 55-63, 2017
11822017
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
JJ Fuster, S MacLauchlan, MA Zuriaga, MN Polackal, AC Ostriker, ...
Science 355 (6327), 842-847, 2017
11272017
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
AR Mridha, A Wree, AAB Robertson, MM Yeh, CD Johnson, ...
Journal of hepatology 66 (5), 1037-1046, 2017
8432017
Human monocytes engage an alternative inflammasome pathway
MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ...
Immunity 44 (4), 833-846, 2016
7302016
Natural product and natural product derived drugs in clinical trials
MS Butler, AAB Robertson, MA Cooper
Natural product reports 31 (11), 1612-1661, 2014
6252014
Fix the antibiotics pipeline
MA Cooper, D Shlaes
Nature 472 (7341), 32-32, 2011
6112011
Label-free screening of bio-molecular interactions
MA Cooper
Analytical and bioanalytical chemistry 377, 834-842, 2003
6102003
Biomarkers in chronic kidney disease: a review
RG Fassett, SK Venuthurupalli, GC Gobe, JS Coombes, MA Cooper, ...
Kidney international 80 (8), 806-821, 2011
5652011
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ...
Science translational medicine 10 (465), eaah4066, 2018
5612018
Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals
KL Ormerod, DLA Wood, N Lachner, SL Gellatly, JN Daly, JD Parsons, ...
Microbiome 4, 1-17, 2016
5502016
Antibiotics in the clinical pipeline in 2013
MS Butler, MA Blaskovich, MA Cooper
The Journal of antibiotics 66 (10), 571-591, 2013
5452013
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle-and high-income countries
BJA: British Journal of Anaesthesia 117 (5), 601-609, 2016
4962016
Tet2-mediated clonal hematopoiesis accelerates heart failure through a mechanism involving the IL-1β/NLRP3 inflammasome
S Sano, K Oshima, Y Wang, S MacLauchlan, Y Katanasaka, M Sano, ...
Journal of the American College of Cardiology 71 (8), 875-886, 2018
4922018
PtdIns (3) P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox
CD Ellson, S Gobert-Gosse, KE Anderson, K Davidson, ...
Nature cell biology 3 (7), 679-682, 2001
4862001
A survey of the 2001 to 2005 quartz crystal microbalance biosensor literature: applications of acoustic physics to the analysis of biomolecular interactions
MA Cooper, VT Singleton
Journal of Molecular Recognition: An Interdisciplinary Journal 20 (3), 154-184, 2007
4832007
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
G Arbore, EE West, R Spolski, AAB Robertson, A Klos, C Rheinheimer, ...
Science 352 (6292), aad1210, 2016
4702016
Aminoglycoside antibiotics in the 21st century
B Becker, MA Cooper
ACS chemical biology 8 (1), 105-115, 2013
4522013
Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice
C Dempsey, AR Araiz, KJ Bryson, O Finucane, C Larkin, EL Mills, ...
Brain, behavior, and immunity 61, 306-316, 2017
4422017
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Articles 1–20