| METLIN: a technology platform for identifying knowns and unknowns C Guijas, JR Montenegro-Burke, X Domingo-Almenara, A Palermo, ... Analytical chemistry 90 (5), 3156-3164, 2018 | 857 | 2018 |
| The runner's high: opioidergic mechanisms in the human brain H Boecker, T Sprenger, ME Spilker, G Henriksen, M Koppenhoefer, ... Cerebral cortex 18 (11), 2523-2531, 2008 | 768 | 2008 |
| Quantitative magnetic resonance imaging analysis of neovasculature volume in carotid atherosclerotic plaque W Kerwin, A Hooker, M Spilker, P Vicini, M Ferguson, T Hatsukami, ... Circulation 107 (6), 851-856, 2003 | 515 | 2003 |
| Conversion of α-linolenic acid in humans is influenced by the absolute amounts of α-linolenic acid and linoleic acid in the diet and not by their ratio PLL Goyens, ME Spilker, PL Zock, MB Katan, RP Mensink The American journal of clinical nutrition 84 (1), 44-53, 2006 | 513 | 2006 |
| Metabolomics activity screening for identifying metabolites that modulate phenotype C Guijas, JR Montenegro-Burke, B Warth, ME Spilker, G Siuzdak Nature biotechnology 36 (4), 316-320, 2018 | 372 | 2018 |
| Biodistribution and pharmacokinetics of the αvβ3-selective tracer 18F-galacto-RGD in cancer patients AJ Beer, R Haubner, M Goebel, S Luderschmidt, ME Spilker, HJ Wester, ... Journal of nuclear medicine 46 (8), 1333-1341, 2005 | 355 | 2005 |
| Compartmental modeling to quantify α-linolenic acid conversion after longer term intake of multiple tracer boluses PLL Goyens, ME Spilker, PL Zock, MB Katan, RP Mensink Journal of lipid research 46 (7), 1474-1483, 2005 | 201 | 2005 |
| Opioidergic activation in the medial pain system after heat pain T Sprenger, M Valet, H Boecker, G Henriksen, ME Spilker, F Willoch, ... PAIN® 122 (1-2), 63-67, 2006 | 137 | 2006 |
| A review of imaging agent development ED Agdeppa, ME Spilker The AAPS journal 11, 286-299, 2009 | 127 | 2009 |
| Metabolite and microbiome interplay in cancer immunotherapy CH Johnson, ME Spilker, L Goetz, SN Peterson, G Siuzdak Cancer research 76 (21), 6146-6152, 2016 | 98 | 2016 |
| Opioidergic changes in the pineal gland and hypothalamus in cluster headache: a ligand PET study T Sprenger, F Willoch, M Miederer, F Schindler, M Valet, A Berthele, ... Neurology 66 (7), 1108-1110, 2006 | 81 | 2006 |
| [18F]FLT–PET Imaging Does Not Always “Light Up” Proliferating Tumor Cells CC Zhang, Z Yan, W Li, K Kuszpit, CL Painter, Q Zhang, PB Lappin, ... Clinical Cancer Research 18 (5), 1303-1312, 2012 | 79* | 2012 |
| The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models S Palsson, TP Hickling, EL Bradshaw-Pierce, M Zager, K Jooss, ... BMC systems biology 7, 1-19, 2013 | 76 | 2013 |
| Applications of quantitative systems pharmacology in model‐informed drug discovery: perspective on impact and opportunities EL Bradshaw, ME Spilker, R Zang, L Bansal, H He, RDO Jones, K Le, ... CPT: pharmacometrics & systems pharmacology 8 (11), 777-791, 2019 | 59 | 2019 |
| Preclinical QSP modeling in the pharmaceutical industry: an IQ consortium survey examining the current landscape MJMA Nijsen, F Wu, L Bansal, E Bradshaw‐Pierce, JR Chan, BM Liederer, ... CPT: pharmacometrics & systems pharmacology 7 (3), 135-146, 2018 | 59 | 2018 |
| Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood–brain barrier A Rohner, ME Spilker, JL Lam, B Pascual, D Bartkowski, QJ Li, AH Yang, ... Molecular cancer therapeutics 11 (1), 57-65, 2012 | 58 | 2012 |
| Force level independent representations of predictive grip force–load force coupling: a PET activation study H Boecker, A Lee, M Mühlau, A Ceballos-Baumann, A Ritzl, ME Spilker, ... Neuroimage 25 (1), 243-252, 2005 | 57 | 2005 |
| Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids ME Kurczy, ZJ Zhu, J Ivanisevic, AM Schuyler, K Lalwani, AF Santidrian, ... Nature communications 6 (1), 5998, 2015 | 54 | 2015 |
| Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging PJ O’Brien, M Lee, ME Spilker, CC Zhang, Z Yan, TC Nichols, W Li, ... Cancer & metabolism 1, 1-14, 2013 | 51 | 2013 |
| A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies SH Liu, Y Gu, B Pascual, Z Yan, M Hallin, C Zhang, C Fan, W Wang, ... Blood advances 1 (15), 1088-1100, 2017 | 45 | 2017 |
