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Berkley Gryder
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Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed
BE Gryder, QH Sodji, AK Oyelere
Future medicinal chemistry 4 (4), 505-524, 2012
4452012
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ...
Nature communications 7 (1), 12320, 2016
4052016
PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ...
Cancer Discovery 7 (8), 884-899, 2017
2502017
Long noncoding RNA PURPL suppresses basal p53 levels and promotes tumorigenicity in colorectal cancer
XL Li, M Subramanian, MF Jones, R Chaudhary, DK Singh, X Zong, ...
Cell reports 20 (10), 2408-2423, 2017
1352017
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou, S Sindiri, A Mendoza, ...
Science translational medicine 10 (448), eaan4470, 2018
1242018
Chemical genomics reveals histone deacetylases are required for core regulatory transcription
BE Gryder, L Wu, GM Woldemichael, S Pomella, TR Quinn, PMC Park, ...
Nature communications 10 (1), 3004, 2019
1232019
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ...
Nature genetics 51 (12), 1714-1722, 2019
1222019
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group
V Patil, W Guerrant, PC Chen, B Gryder, DB Benicewicz, SI Khan, ...
Bioorganic & medicinal chemistry 18 (1), 415-425, 2010
1122010
MultiDimensional ClinOmics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: a report from the center for cancer research
W Chang, AS Brohl, R Patidar, S Sindiri, JF Shern, JS Wei, YK Song, ...
Clinical cancer research 22 (15), 3810-3820, 2016
1072016
Histone deacetylase inhibitors equipped with estrogen receptor modulation activity
BE Gryder, MK Rood, KA Johnson, V Patil, ED Raftery, LPD Yao, M Rice, ...
Journal of medicinal chemistry 56 (14), 5782-5796, 2013
982013
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a therapeutic strategy for p53 activation in high-risk neuroblastoma
V Veschi, Z Liu, TC Voss, L Ozbun, B Gryder, C Yan, Y Hu, A Ma, J Jin, ...
Cancer cell 31 (1), 50-63, 2017
892017
Antiandrogen gold nanoparticles dual-target and overcome treatment resistance in hormone-insensitive prostate cancer cells
EC Dreaden, BE Gryder, LA Austin, BA Tene Defo, SC Hayden, M Pi, ...
Bioconjugate chemistry 23 (8), 1507-1512, 2012
872012
Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3
R Chaudhary, B Gryder, WS Woods, M Subramanian, MF Jones, XL Li, ...
Elife 6, e23244, 2017
832017
Selectively targeting prostate cancer with antiandrogen equipped histone deacetylase inhibitors
BE Gryder, MJ Akbashev, MK Rood, ED Raftery, WM Meyers, P Dillard, ...
ACS chemical biology 8 (11), 2550-2560, 2013
812013
Selectively targeting prostate cancer with antiandrogen equipped histone deacetylase inhibitors
BE Gryder, MJ Akbashev, MK Rood, ED Raftery, WM Meyers, P Dillard, ...
ACS chemical biology 8 (11), 2550-2560, 2013
812013
Insights into pediatric rhabdomyosarcoma research: Challenges and goals
ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ...
Pediatric blood & cancer 66 (10), e27869, 2019
702019
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
IM Tenente, MN Hayes, MS Ignatius, K McCarthy, M Yohe, S Sindiri, ...
Elife 6, e19214, 2017
682017
Vangl2/RhoA signaling pathway regulates stem cell self-renewal programs and growth in rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
662018
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
AM Chiarella, KV Butler, BE Gryder, D Lu, TA Wang, X Yu, S Pomella, ...
Nature biotechnology 38 (1), 50-55, 2020
592020
Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma
D Bogen, JS Wei, DO Azorsa, P Ormanoglu, E Buehler, R Guha, JM Keller, ...
Oncotarget 6 (34), 35247, 2015
582015
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