Jessica Thomaston
Title
Cited by
Cited by
Year
High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction
JL Thomaston, M Alfonso-Prieto, RA Woldeyes, JS Fraser, ML Klein, ...
Proceedings of the National Academy of Sciences 112 (46), 14260-14265, 2015
732015
High-density grids for efficient data collection from multiple crystals
EL Baxter, L Aguila, R Alonso-Mori, CO Barnes, CA Bonagura, ...
Acta Crystallographica Section D: Structural Biology 72 (1), 2-11, 2016
482016
Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters
JL Thomaston, NF Polizzi, A Konstantinidi, J Wang, A Kolocouris, ...
Journal of the American Chemical Society 140 (45), 15219-15226, 2018
392018
XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction
JL Thomaston, RA Woldeyes, T Nakane, A Yamashita, T Tanaka, ...
Proceedings of the National Academy of Sciences 114 (51), 13357-13362, 2017
372017
Packing of apolar side chains enables accurate design of highly stable membrane proteins
M Mravic, JL Thomaston, M Tucker, PE Solomon, L Liu, WF DeGrado
Science 363 (6434), 1418-1423, 2019
352019
Crystal structure of the drug‐resistant S31N influenza M2 proton channel
JL Thomaston, WF DeGrado
Protein Science 25 (8), 1551-1554, 2016
322016
Detection of drug‐induced conformational change of a transmembrane protein in lipid bilayers using site‐directed spin labeling
JL Thomaston, PA Nguyen, EC Brown, MA Upshur, J Wang, WF DeGrado, ...
Protein Science 22 (1), 65-73, 2013
192013
C‐terminal juxtamembrane region of full‐length M2 protein forms a membrane surface associated amphipathic helix
S Huang, B Green, M Thompson, R Chen, J Thomaston, WF DeGrado, ...
Protein Science 24 (3), 426-429, 2015
112015
X-ray crystal structure of the influenza A M2 proton channel S31N mutant in two conformational states: an open and shut case
JL Thomaston, Y Wu, N Polizzi, L Liu, J Wang, WF DeGrado
Journal of the American Chemical Society 141 (29), 11481-11488, 2019
72019
X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance
JL Thomaston, A Konstantinidi, L Liu, G Lambrinidis, J Tan, M Caffrey, ...
Biochemistry 59 (4), 627-634, 2020
62020
Selected publications
L Chen
Acc Chem Res 36, 713-722, 2003
12003
STRUCTURAL BASIS OF ADAMANTANE RESISTANCE IN THE INFLUENZA A M2 PROTON CHANNEL
J Thomaston, Y Wu, L Liu, J Wang, W DeGrado
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 75, E140-E140, 2019
2019
Structural characterization of adamantane-resistant mutants of the influenza M2 proton channel
JL Thomaston, WF DeGrado
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 74, A187-A187, 2018
2018
Proton Stabilization and Conduction Pathway in the Matrix Protein M2
HT Kratochvil, JL Thomaston, F Gai, WF DeGrado
Biophysical Journal 114 (3), 240a-241a, 2018
2018
Molecular Design and X-Ray Crystal Structure of Engineered Phospholamban Transmembrane Variant
M Mravic, J Thomaston, WF DeGrado
Biophysical Journal 114 (3), 36a, 2018
2018
X-Ray Crystal Structures of the Influenza a M2 Proton Channel Bound to Amantadine, Rimantadine, and Inhibiting Compounds
JL Thomaston, WF DeGrado
Biophysical Journal 114 (3), 204a, 2018
2018
X-ray crystal structures of the influenza A M2 proton channel
JL Thomaston
University of California–San Francisco, 2018
2018
X-ray Crystal Structures of the Influenza A M2 Proton Channel Bound to Amantadine, Rimantadine, and Inhibitors
J Thomaston, W DeGrado
PROTEIN SCIENCE 26, 136-136, 2017
2017
X-‐ray crystal structures of the influenza A M2 proton channel bound to amantadine, rimantadine, and inhibiting compounds
JL Thomaston, WF DeGrado
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A78-A78, 2017
2017
XFEL structures of the influenza M2 proton channel at 1.4 angstrom: room temperature water networks and insights into proton conduction
JL Thomaston, RA Woldeyes, T Nakane, K Koiwai, A Yamashita, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A40-A40, 2017
2017
The system can't perform the operation now. Try again later.
Articles 1–20