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Chia-Yen Chen
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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
M Verbanck, CY Chen, B Neale, R Do
Nature genetics 50 (5), 693-698, 2018
40072018
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardińas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
1354*2022
Polygenic prediction via Bayesian regression and continuous shrinkage priors
T Ge, CY Chen, Y Ni, YCA Feng, JW Smoller
Nature communications 10 (1), 1776, 2019
9902019
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
8542022
FinnGen provides genetic insights from a well-phenotyped isolated population
MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ...
Nature 613 (7944), 508-518, 2023
7532023
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
5922019
Assessment of bidirectional relationships between physical activity and depression among adults: a 2-sample Mendelian randomization study
KW Choi, CY Chen, MB Stein, YC Klimentidis, MJ Wang, KC Koenen, ...
JAMA psychiatry 76 (4), 399-408, 2019
532*2019
Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations
RE Peterson, K Kuchenbaecker, RK Walters, CY Chen, AB Popejoy, ...
Cell 179 (3), 589-603, 2019
5202019
Comparative genetic architectures of schizophrenia in East Asian and European populations
M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma, H Gaspar, M Ikeda, ...
Nature genetics 51 (12), 1670-1678, 2019
5102019
Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability
LE Duncan, A Ratanatharathorn, AE Aiello, LM Almli, AB Amstadter, ...
Molecular psychiatry 23 (3), 666-673, 2018
4572018
International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci
CM Nievergelt, AX Maihofer, T Klengel, EG Atkinson, CY Chen, KW Choi, ...
Nature communications 10 (1), 4558, 2019
4432019
Improving polygenic prediction in ancestrally diverse populations
Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ...
Nature genetics 54 (5), 573-580, 2022
2762022
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank
JD Szustakowski, S Balasubramanian, E Kvikstad, S Khalid, PG Bronson, ...
Nature genetics 53 (7), 942-948, 2021
2762021
Being overweight or obese and risk of developing rheumatoid arthritis among women: a prospective cohort study
B Lu, LT Hiraki, JA Sparks, S Malspeis, CY Chen, JA Awosogba, ...
Annals of the rheumatic diseases 73 (11), 1914-1922, 2014
2662014
Phenome-wide heritability analysis of the UK Biobank
T Ge, CY Chen, BM Neale, MR Sabuncu, JW Smoller
PLoS genetics 13 (4), e1006711, 2017
2352017
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan
CJ Chen, LI Hsu, CH Wang, WL Shih, YH Hsu, MP Tseng, YC Lin, ...
Toxicology and applied pharmacology 206 (2), 198-206, 2005
2352005
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
P Gharahkhani, E Jorgenson, P Hysi, AP Khawaja, S Pendergrass, X Han, ...
Nature communications 12 (1), 1258, 2021
2182021
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four health care systems
AB Zheutlin, J Dennis, R Karlsson Linnér, A Moscati, N Restrepo, ...
American Journal of Psychiatry 176 (10), 846-855, 2019
1862019
Improved ancestry inference using weights from external reference panels
CY Chen, S Pollack, DJ Hunter, JN Hirschhorn, P Kraft, AL Price
Bioinformatics 29 (11), 1399-1406, 2013
1822013
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ...
Cell Genomics 2 (10), 2022
1812022
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