IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer S Grivennikov, E Karin, J Terzic, D Mucida, GY Yu, S Vallabhapurapu, ... Cancer cell 15 (2), 103-113, 2009 | 2456 | 2009 |
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression EJ Park, JH Lee, GY Yu, G He, SR Ali, RG Holzer, CH Österreicher, ... Cell 140 (2), 197-208, 2010 | 1957 | 2010 |
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth SI Grivennikov, K Wang, D Mucida, CA Stewart, B Schnabl, D Jauch, ... Nature 491 (7423), 254-258, 2012 | 1372 | 2012 |
Hepatocyte necrosis induced by oxidative stress and IL-1α release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis T Sakurai, G He, A Matsuzawa, GY Yu, S Maeda, G Hardiman, M Karin Cancer cell 14 (2), 156-165, 2008 | 579 | 2008 |
Hepatocyte IKKβ/NF-κB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation G He, GY Yu, V Temkin, H Ogata, C Kuntzen, T Sakurai, W Sieghart, ... Cancer cell 17 (3), 286-297, 2010 | 490 | 2010 |
Palmitoylation and polymerization of hepatitis C virus NS4B protein GY Yu, KJ Lee, L Gao, MMC Lai Journal of virology 80 (12), 6013-6023, 2006 | 188 | 2006 |
Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish DW Yeh, YL Liu, YC Lo, CH Yuh, GY Yu, JF Lo, Y Luo, R Xiang, ... Proceedings of the National Academy of Sciences 110 (51), 20711-20716, 2013 | 135 | 2013 |
IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ LC Hsu, T Enzler, J Seita, AM Timmer, CY Lee, TY Lai, GY Yu, LC Lai, ... Nature immunology 12 (2), 144-150, 2011 | 132 | 2011 |
The ubiquitin-proteasome system facilitates the transfer of murine coronavirus from endosome to cytoplasm during virus entry GY Yu, MMC Lai Journal of virology 79 (1), 644-648, 2005 | 112 | 2005 |
Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine production GY Yu, G He, CY Li, M Tang, S Grivennikov, WT Tsai, MS Wu, CW Hsu, ... Molecular cell 48 (2), 313-321, 2012 | 76 | 2012 |
Multiple type A/B heterogeneous nuclear ribonucleoproteins (hnRNPs) can replace hnRNP A1 in mouse hepatitis virus RNA synthesis ST Shi, GY Yu, MMC Lai Journal of virology 77 (19), 10584-10593, 2003 | 64 | 2003 |
Immunostimulatory activities of CpG-oligodeoxynucleotides in teleosts: toll-like receptors 9 and 21 CY Lai, GY Yu, Y Luo, R Xiang, TH Chuang Frontiers in immunology 10, 179, 2019 | 53 | 2019 |
Recent advances in the development of toll-like receptor agonist-based vaccine adjuvants for infectious diseases JX Yang, JC Tseng, GY Yu, Y Luo, CYF Huang, YR Hong, TH Chuang Pharmaceutics 14 (2), 423, 2022 | 48 | 2022 |
The Effects of Aβ1-42 Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2 JTA Hsu, CF Tien, GY Yu, S Shen, YH Lee, PC Hsu, Y Wang, PK Chao, ... International Journal of Molecular Sciences 22 (15), 8226, 2021 | 48 | 2021 |
Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy WT Tsai, YC Lo, MS Wu, CY Li, YP Kuo, YH Lai, Y Tsai, KC Chen, ... Journal of biological chemistry 291 (37), 19299-19311, 2016 | 40 | 2016 |
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation WC Hsu, MY Chen, SC Hsu, LR Huang, CY Kao, WH Cheng, CH Pan, ... Proceedings of the National Academy of Sciences 115 (34), E8027-E8036, 2018 | 39 | 2018 |
CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses DW Yeh, CY Lai, YL Liu, CH Lu, PH Tseng, CH Yuh, GY Yu, SJ Liu, ... Scientific reports 7 (1), 17297, 2017 | 28 | 2017 |
Establishment of a mouse model for the complete mosquito-mediated transmission cycle of Zika virus YP Kuo, KN Tsai, YC Luo, PJ Chung, YW Su, Y Teng, MS Wu, YF Lin, ... PLoS Neglected Tropical Diseases 12 (4), e0006417, 2018 | 26 | 2018 |
Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis Y Simonin, S Vegna, L Akkari, D Grégoire, E Antoine, J Piette, N Floc'h, ... PLoS pathogens 9 (3), e1003234, 2013 | 26 | 2013 |
Zika virus NS3 protease pharmacophore anchor model and drug discovery N Pathak, YP Kuo, TY Chang, CT Huang, HC Hung, JTA Hsu, GY Yu, ... Scientific reports 10 (1), 8929, 2020 | 25 | 2020 |