| Enhanced nonenzymatic RNA copying with 2-aminoimidazole activated nucleotides L Li, N Prywes, CP Tam, DK O’flaherty, VS Lelyveld, EC Izgu, A Pal, ... Journal of the American Chemical Society 139 (5), 1810-1813, 2017 | 158 | 2017 |
| Enantioselective Pd (II)-catalyzed aerobic oxidative amidation of alkenes and insights into the role of electronic asymmetry in pyridine-oxazoline ligands RI McDonald, PB White, AB Weinstein, CP Tam, SS Stahl Organic letters 13 (11), 2830-2833, 2011 | 135 | 2011 |
| Common and potentially prebiotic origin for precursors of nucleotide synthesis and activation AC Fahrenbach, C Giurgiu, CP Tam, L Li, Y Hongo, M Aono, JW Szostak Journal of the American Chemical Society 139 (26), 8780-8783, 2017 | 85 | 2017 |
| The mechanism of nonenzymatic template copying with imidazole‐activated nucleotides T Walton, W Zhang, L Li, CP Tam, JW Szostak Angewandte Chemie International Edition 58 (32), 10812-10819, 2019 | 67 | 2019 |
| Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex W Zhang, CP Tam, T Walton, AC Fahrenbach, G Birrane, JW Szostak Proceedings of the National Academy of Sciences 114 (29), 7659-7664, 2017 | 33 | 2017 |
| Structure-guided development of covalent TAK1 inhibitors L Tan, D Gurbani, EL Weisberg, JC Hunter, L Li, DS Jones, SB Ficarro, ... Bioorganic & medicinal chemistry 25 (3), 838-846, 2017 | 33 | 2017 |
| Unusual base-pairing interactions in monomer–template complexes W Zhang, CP Tam, J Wang, JW Szostak ACS Central Science 2 (12), 916-926, 2016 | 30 | 2016 |
| Bidirectional direct sequencing of noncanonical RNA by two-dimensional analysis of mass chromatograms A Björkbom, VS Lelyveld, S Zhang, W Zhang, CP Tam, JC Blain, ... Journal of the American Chemical Society 137 (45), 14430-14438, 2015 | 28 | 2015 |
| Structural rationale for the enhanced catalysis of nonenzymatic RNA primer extension by a downstream oligonucleotide W Zhang, CP Tam, L Zhou, SS Oh, J Wang, JW Szostak Journal of the American Chemical Society 140 (8), 2829-2840, 2018 | 27 | 2018 |
| A mechanistic explanation for the regioselectivity of nonenzymatic RNA primer extension C Giurgiu, L Li, DK O’Flaherty, CP Tam, JW Szostak Journal of the American Chemical Society 139 (46), 16741-16747, 2017 | 23 | 2017 |
| Downstream oligonucleotides strongly enhance the affinity of GMP to RNA primer–template complexes CP Tam, AC Fahrenbach, A Björkbom, N Prywes, EC Izgu, JW Szostak Journal of the American Chemical Society 139 (2), 571-574, 2017 | 21 | 2017 |
| Selective Access to Trisubstituted Macrocyclic E- and Z-Alkenes from the Ring-Closing Metathesis of Vinylsiloxanes Y Wang, M Jimenez, P Sheehan, C Zhong, AW Hung, CP Tam, ... Organic letters 15 (6), 1218-1221, 2013 | 21 | 2013 |
| Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization W Zhang, C Kim, CP Tam, V Lelyveld, S Bala, J Chaput, JW Szostak Nucleic Acids Research 49 (2), 646-656, 2021 | 12 | 2021 |
| Synthesis of a nonhydrolyzable nucleotide phosphoroimidazolide analogue that catalyzes nonenzymatic RNA primer extension CP Tam, L Zhou, AC Fahrenbach, W Zhang, T Walton, JW Szostak Journal of the American Chemical Society 140 (2), 783-792, 2018 | 12 | 2018 |
| Catalytic Metal Ion–Substrate Coordination during Nonenzymatic RNA Primer Extension Z Fang, LT Pazienza, J Zhang, CP Tam, JW Szostak Journal of the American Chemical Society, 2024 | | 2024 |
| Nonhydrolyzable Ribonucleotide Phosphoroimidazolide Analogues for Mechanistic Studies of Nonenzymatic RNA Replication CP Tam PQDT-Global, 2018 | | 2018 |
