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Eliot T. McKinley
Eliot T. McKinley
Principal Bioimaging Data Scientist, GSK
Verifierad e-postadress på gsk.com - Startsida
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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase
JT Garrett, MG Olivares, C Rinehart, ND Granja-Ingram, V Sánchez, ...
Proceedings of the National Academy of Sciences 108 (12), 5021-5026, 2011
5152011
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
3812020
Transfer of functional cargo in exomeres
Q Zhang, JN Higginbotham, DK Jeppesen, YP Yang, W Li, ET McKinley, ...
Cell reports 27 (3), 940-954. e6, 2019
3192019
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Q Zhang, DK Jeppesen, JN Higginbotham, R Graves-Deal, VQ Trinh, ...
Nature cell biology 23 (12), 1240-1254, 2021
2162021
Unsupervised trajectory analysis of single-cell RNA-seq and imaging data reveals alternative tuft cell origins in the gut
CA Herring, A Banerjee, ET McKinley, AJ Simmons, J Ping, JT Roland, ...
Cell systems 6 (1), 37-51. e9, 2018
1982018
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ...
Cell 184 (26), 6262-6280. e26, 2021
1532021
Succinate produced by intestinal microbes promotes specification of tuft cells to suppress ileal inflammation
A Banerjee, CA Herring, B Chen, H Kim, AJ Simmons, AN Southard-Smith, ...
Gastroenterology 159 (6), 2101-2115. e5, 2020
1482020
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity
ET McKinley, Y Sui, Y Al-Kofahi, BA Millis, MJ Tyska, JT Roland, ...
JCI insight 2 (11), 2017
1342017
Limits of [18F]-FLT PET as a Biomarker of Proliferation in Oncology
ET McKinley, GD Ayers, RA Smith, SA Saleh, P Zhao, MK Washington, ...
PloS one 8 (3), e58938, 2013
1312013
Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements
GD Ayers, ET McKinley, P Zhao, JM Fritz, RE Metry, BC Deal, KM Adlerz, ...
Journal of Ultrasound in Medicine 29 (6), 891-901, 2010
1242010
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer
HC Manning, NB Merchant, AC Foutch, JM Virostko, SK Wyatt, C Shah, ...
Clinical cancer research 14 (22), 7413-7422, 2008
1232008
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging
D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ...
Nature methods 19 (3), 311-315, 2022
1202022
Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer
C Shah, TW Miller, SK Wyatt, ET McKinley, MG Olivares, V Sanchez, ...
Clinical Cancer Research 15 (14), 4712-4721, 2009
1022009
In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy
X Jiang, H Li, J Xie, ET McKinley, P Zhao, JC Gore, J Xu
Magnetic resonance in medicine 78 (1), 156-164, 2017
942017
Interpreting heterogeneity in intestinal tuft cell structure and function
A Banerjee, ET McKinley, J von Moltke, RJ Coffey, KS Lau
The Journal of clinical investigation 128 (5), 1711-1719, 2018
862018
Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2, 5-dimethoxybenzyl)-2-phenoxyaniline
JR Buck, ET McKinley, MR Hight, A Fu, D Tang, RA Smith, MN Tantawy, ...
Journal of Nuclear Medicine 52 (1), 107-114, 2011
732011
Quantitative preclinical imaging of TSPO expression in glioma using N, N-diethyl-2-(2-(4-(2-18F-fluoroethoxy) phenyl)-5, 7-dimethylpyrazolo [1, 5-a] pyrimidin-3-yl) acetamide
D Tang, MR Hight, ET McKinley, A Fu, JR Buck, RA Smith, MN Tantawy, ...
Journal of Nuclear Medicine 53 (2), 287-294, 2012
712012
Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis
AE Powell, G Vlacich, ZY Zhao, ET McKinley, MK Washington, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 307 (1 …, 2014
682014
Magnetic resonance imaging of mean cell size in human breast tumors
J Xu, X Jiang, H Li, LR Arlinghaus, ET McKinley, SP Devan, BM Hardy, ...
Magnetic resonance in medicine 83 (6), 2002-2014, 2020
602020
18FDG-PET Predicts Pharmacodynamic Response to OSI-906, a Dual IGF-1R/IR Inhibitor, in Preclinical Mouse Models of Lung Cancer
ET McKinley, JE Bugaj, P Zhao, S Guleryuz, C Mantis, PC Gokhale, ...
Clinical Cancer Research 17 (10), 3332-3340, 2011
582011
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