Huaxi Xu
Huaxi Xu
rockefeller or burnham or sanford-burnham or einstein or xiamen
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Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
CC Liu, T Kanekiyo, H Xu, G Bu
Nature Reviews Neurology 9 (2), 106-118, 2013
Intraneuronal Aβ42 accumulation in human brain
GK Gouras, J Tsai, J Naslund, B Vincent, M Edgar, F Checler, ...
The American journal of pathology 156 (1), 15-20, 2000
APP processing in Alzheimer's disease
Y Zhang, R Thompson, H Zhang, H Xu
Molecular brain 4 (1), 1-13, 2011
Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
RH Takahashi, TA Milner, F Li, EE Nam, MA Edgar, H Yamaguchi, ...
The American journal of pathology 161 (5), 1869-1879, 2002
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
H Xu, GK Gouras, JP Greenfield, B Vincent, J Naslund, L Mazzarelli, ...
Nature medicine 4 (4), 447-451, 1998
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
L Gasparini, GK Gouras, R Wang, RS Gross, MF Beal, P Greengard, H Xu
Journal of Neuroscience 21 (8), 2561-2570, 2001
Chaperones increase association of tau protein with microtubules
F Dou, WJ Netzer, K Tanemura, F Li, FU Hartl, A Takashima, GK Gouras, ...
Proceedings of the National Academy of Sciences 100 (2), 721-726, 2003
Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes
KS Vetrivel, H Cheng, W Lin, T Sakurai, T Li, N Nukina, PC Wong, H Xu, ...
Journal of Biological Chemistry 279 (43), 44945-44954, 2004
Inhibition of amyloid-β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761
Y Luo, JV Smith, V Paramasivam, A Burdick, KJ Curry, JP Buford, I Khan, ...
Proceedings of the national academy of sciences 99 (19), 12197-12202, 2002
ApoE and Aβ in Alzheimer’s disease: accidental encounters or partners?
T Kanekiyo, H Xu, G Bu
Neuron 81 (4), 740-754, 2014
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
JP Greenfield, J Tsai, GK Gouras, B Hai, G Thinakaran, F Checler, ...
Proceedings of the National Academy of Sciences 96 (2), 742-747, 1999
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
Y Chen, K Zhou, R Wang, Y Liu, YD Kwak, T Ma, RC Thompson, Y Zhao, ...
Proceedings of the National Academy of Sciences 106 (10), 3907-3912, 2009
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease
S Tu, S Okamoto, SA Lipton, H Xu
Molecular neurodegeneration 9 (1), 1-12, 2014
Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation
X Zhang, K Zhou, R Wang, J Cui, SA Lipton, FF Liao, H Xu, Y Zhang
Journal of Biological Chemistry 282 (15), 10873-10880, 2007
Does insulin dysfunction play a role in Alzheimer's disease?
L Gasparini, WJ Netzer, P Greengard, H Xu
Trends in pharmacological sciences 23 (6), 288-293, 2002
Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides
GK Gouras, H Xu, RS Gross, JP Greenfield, B Hai, R Wang, P Greengard
Proceedings of the national academy of sciences 97 (3), 1202-1205, 2000
Generation of Alzheimer β-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
H Xu, D Sweeney, R Wang, G Thinakaran, ACY Lo, SS Sisodia, ...
Proceedings of the National Academy of Sciences 94 (8), 3748-3752, 1997
Proteolytic processing of Alzheimer’s β‐amyloid precursor protein
H Zhang, Q Ma, Y Zhang, H Xu
Journal of Neurochemistry: REVIEW 120, 9-21, 2012
Potential roles of insulin and IGF-1 in Alzheimer's disease
L Gasparini, H Xu
Trends in neurosciences 26 (8), 404-406, 2003
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1
W Luo, H Wang, H Li, BS Kim, S Shah, HJ Lee, G Thinakaran, TW Kim, ...
Journal of Biological Chemistry 278 (10), 7850-7854, 2003
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