Oliver Fleetwood
Oliver Fleetwood
CTO, Alex Therapeutics
Verifierad e-postadress på alextherapeutics.com - Startsida
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Molecular insights from conformational ensembles via machine learning
O Fleetwood, MA Kasimova, AM Westerlund, L Delemotte
Biophysical journal 118 (3), 765-780, 2020
342020
Energy landscapes reveal agonist control of G protein-coupled receptor activation via microswitches
O Fleetwood, P Matricon, J Carlsson, L Delemotte
Biochemistry 59 (7), 880-891, 2020
24*2020
Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling
O Fleetwood, J Carlsson, L Delemotte
Elife 10, e60715, 2021
82021
Network analysis reveals how lipids and other cofactors influence membrane protein allostery
AM Westerlund, O Fleetwood, S Perez-Conesa, L Delemotte
The Journal of Chemical Physics 153 (14), 141103, 2020
62020
Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
Y Chen, O Fleetwood, S Pérez-Conesa, L Delemotte
Journal of chemical information and modeling 61 (12), 6024-6037, 2021
2021
Elucidation of G-protein-coupled receptor activation via data-driven modeling
O Fleetwood, Y Chen, S Perez-Conesa, L Delemotte
European Biophysics Journal 50 (SUPPL 1), 74-74, 2021
2021
New approaches to data-driven analysis and enhanced sampling simulations of G protein-coupled receptors
O Fleetwood
KTH Royal Institute of Technology, 2021
2021
All Articles August 26, 2020
C Upadhyay, R Feyznezhad, L Cao, KW Chan, K Liu, W Yang, H Zhang, ...
Signal, 2020
2020
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Artiklar 1–8