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Ute A. Hellmich
Ute A. Hellmich
Friedrich-Schiller-University Jena, Germany
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Year
Diverse relations between ABC transporters and lipids: An overview
J Neumann, D Rose-Sperling, UA Hellmich
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (4), 605-618, 2017
1552017
Phosphatidylinositol-4, 5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli
A Garcia-Elias, S Mrkonjić, C Pardo-Pastor, H Inada, UA Hellmich, ...
Proceedings of the National Academy of Sciences 110 (23), 9553-9558, 2013
1402013
Comparison of mechanistic transport cycle models of ABC exporters
D Szöllősi, D Rose-Sperling, UA Hellmich, T Stockner
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (4), 818-832, 2018
1132018
Structural biology of TRP channels
UA Hellmich, R Gaudet
Mammalian Transient Receptor Potential (TRP) Cation Channels: Volume II, 963-990, 2014
1052014
Quantum chemical-based protocol for the rational design of covalent inhibitors
T Schirmeister, J Kesselring, S Jung, TH Schneider, A Weickert, J Becker, ...
Journal of the American Chemical Society 138 (27), 8332-8335, 2016
762016
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus
A Zutz, J Hoffmann, UA Hellmich, C Glaubitz, B Ludwig, B Brutschy, ...
Journal of biological chemistry 286 (9), 7104-7115, 2011
742011
Proline-based allosteric inhibitors of Zika and Dengue virus NS2B/NS3 proteases
B Millies, F von Hammerstein, A Gellert, S Hammerschmidt, F Barthels, ...
Journal of Medicinal Chemistry 62 (24), 11359-11382, 2019
732019
Solid-state NMR and functional studies on proteorhodopsin
N Pfleger, AC Wörner, J Yang, S Shastri, UA Hellmich, L Aslimovska, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (6), 697-705, 2009
672009
Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy
UA Hellmich, S Lyubenova, E Kaltenborn, R Doshi, HW van Veen, ...
Journal of the American Chemical Society 134 (13), 5857-5862, 2012
632012
Dipeptidyl nitroalkenes as potent reversible inhibitors of cysteine proteases rhodesain and cruzain
A Latorre, T Schirmeister, J Kesselring, S Jung, P Johe, UA Hellmich, ...
ACS medicinal chemistry letters 7 (12), 1073-1076, 2016
592016
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of Neglected Tropical Diseases (NTDs)
S Previti, R Ettari, S Cosconati, G Amendola, K Chouchene, A Wagner, ...
Journal of Medicinal Chemistry 60 (16), 6911-6923, 2017
562017
Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR
SJ Ullrich, UA Hellmich, S Ullrich, C Glaubitz
Nature chemical biology 7 (5), 263-270, 2011
532011
Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA–protein interactions during small ribosomal subunit biogenesis
UA Hellmich, BL Weis, A Lioutikov, JP Wurm, M Kaiser, NA Christ, ...
Proceedings of the National Academy of Sciences 110 (38), 15253-15258, 2013
412013
19F NMR as a versatile tool to study membrane protein structure and dynamics
D Rose-Sperling, MA Tran, LM Lauth, B Goretzki, UA Hellmich
Biological chemistry 400 (10), 1277-1288, 2019
382019
The solution structure of the lantibiotic immunity protein NisI and its interactions with nisin
C Hacker, NA Christ, E Duchardt-Ferner, S Korn, C Göbl, L Berninger, ...
Journal of Biological Chemistry 290 (48), 28869-28886, 2015
372015
NMR and EPR studies of membrane transporters
UA Hellmich, C Glaubitz
Walter de Gruyter 390 (8), 815-834, 2009
352009
Structural basis of TRPV4 N terminus interaction with syndapin/PACSIN1-3 and PIP2
B Goretzki, NA Glogowski, E Diehl, E Duchardt-Ferner, C Hacker, ...
Structure 26 (12), 1583-1593. e5, 2018
332018
Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk
JC Heiby, B Goretzki, CM Johnson, UA Hellmich, H Neuweiler
Nature communications 10 (1), 4378, 2019
312019
Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance
A Siarheyeva, JJ Lopez, I Lehner, UA Hellmich, HW van Veen, C Glaubitz
Biochemistry 46 (11), 3075-3083, 2007
312007
Unstructural biology of TRP ion channels: the role of intrinsically disordered regions in channel function and regulation
B Goretzki, C Guhl, F Tebbe, JM Harder, UA Hellmich
Journal of Molecular Biology 433 (17), 166931, 2021
302021
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Articles 1–20