Ute A. Hellmich
Ute A. Hellmich
Friedrich-Schiller-University Jena, Germany
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Phosphatidylinositol-4, 5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli
A Garcia-Elias, S Mrkonjić, C Pardo-Pastor, H Inada, UA Hellmich, ...
Proceedings of the National Academy of Sciences 110 (23), 9553-9558, 2013
Diverse relations between ABC transporters and lipids: An overview
J Neumann, D Rose-Sperling, UA Hellmich
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (4), 605-618, 2017
Comparison of mechanistic transport cycle models of ABC exporters
D Szöllősi, D Rose-Sperling, UA Hellmich, T Stockner
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (4), 818-832, 2018
Structural biology of TRP channels
UA Hellmich, R Gaudet
Mammalian Transient Receptor Potential (TRP) Cation Channels, 963-990, 2014
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus
A Zutz, J Hoffmann, UA Hellmich, C Glaubitz, B Ludwig, B Brutschy, ...
Journal of Biological Chemistry 286 (9), 7104-7115, 2011
Solid-state NMR and functional studies on proteorhodopsin
N Pfleger, AC Wörner, J Yang, S Shastri, UA Hellmich, L Aslimovska, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (6), 697-705, 2009
Quantum chemical-based protocol for the rational design of covalent inhibitors
T Schirmeister, J Kesselring, S Jung, TH Schneider, A Weickert, J Becker, ...
Journal of the American Chemical Society 138 (27), 8332-8335, 2016
Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy
UA Hellmich, S Lyubenova, E Kaltenborn, R Doshi, HW van Veen, ...
Journal of the American Chemical Society 134 (13), 5857-5862, 2012
Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR
SJ Ullrich, UA Hellmich, S Ullrich, C Glaubitz
Nature chemical biology 7 (5), 263-270, 2011
Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA–protein interactions during small ribosomal subunit biogenesis
UA Hellmich, BL Weis, A Lioutikov, JP Wurm, M Kaiser, NA Christ, ...
Proceedings of the National Academy of Sciences 110 (38), 15253-15258, 2013
Dipeptidyl nitroalkenes as potent reversible inhibitors of cysteine proteases rhodesain and cruzain
A Latorre, T Schirmeister, J Kesselring, S Jung, P Johé, UA Hellmich, ...
ACS medicinal chemistry letters 7 (12), 1073-1076, 2016
Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance
A Siarheyeva, JJ Lopez, I Lehner, UA Hellmich, HW van Veen, C Glaubitz
Biochemistry 46 (11), 3075-3083, 2007
NMR and EPR studies of membrane transporters
UA Hellmich, C Glaubitz
Biological chemistry 390 (8), 815-834, 2009
The solution structure of the lantibiotic immunity protein NisI and its interactions with nisin
C Hacker, NA Christ, E Duchardt-Ferner, S Korn, C Göbl, L Berninger, ...
Journal of Biological Chemistry 290 (48), 28869-28886, 2015
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of Neglected Tropical Diseases (NTDs)
S Previti, R Ettari, S Cosconati, G Amendola, K Chouchene, A Wagner, ...
Journal of medicinal chemistry 60 (16), 6911-6923, 2017
Caught in the act: ATP hydrolysis of an ABC-multidrug transporter followed by real-time magic angle spinning NMR
UA Hellmich, W Haase, S Velamakanni, HW van Veen, C Glaubitz
FEBS letters 582 (23-24), 3557-3562, 2008
The First structure of a lantibiotic immunity protein, SpaI from Bacillus subtilis, reveals a novel fold
NA Christ, S Bochmann, D Gottstein, E Duchardt-Ferner, UA Hellmich, ...
Journal of Biological Chemistry 287 (42), 35286-35298, 2012
19F‐MAS NMR on Proteorhodopsin: Enhanced Protocol for Site‐Specific Labeling for General Application to Membrane Proteins
UA Hellmich, N Pfleger, C Glaubitz
Photochemistry and photobiology 85 (2), 535-539, 2009
Proline-based allosteric inhibitors of Zika and Dengue virus NS2B/NS3 proteases
B Millies, F von Hammerstein, A Gellert, S Hammerschmidt, F Barthels, ...
Journal of medicinal chemistry 62 (24), 11359-11382, 2019
Effects of nucleotide binding to LmrA: a combined MAS-NMR and solution NMR study
UA Hellmich, L Mönkemeyer, S Velamakanni, HW van Veen, C Glaubitz
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (12), 3158-3165, 2015
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