Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery N Boehnke, JP Straehla, HC Safford, M Kocak, MG Rees, M Ronan, ... Science 377 (6604), eabm5551, 2022 | 90 | 2022 |
A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles JP Straehla, C Hajal, HC Safford, GS Offeddu, N Boehnke, TG Dacoba, ... Proceedings of the National Academy of Sciences 119 (23), e2118697119, 2022 | 51 | 2022 |
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ... Journal of the American Chemical Society 145 (8), 4691-4706, 2023 | 43 | 2023 |
β-Lactamase triggered visual detection of bacteria using cephalosporin functionalized biomaterials D Alkekhia, H Safford, S Shukla, R Hopson, A Shukla Chemical Communications 56 (75), 11098-11101, 2020 | 9 | 2020 |
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta HC Safford, KL Swingle, HC Geisler, AG Hamilton, AS Thatte, ... Small, 2303568, 2023 | 7 | 2023 |
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ... Small 20 (11), 2304378, 2024 | 6 | 2024 |
Rational design of nanomedicine for placental disorders: birthing a new era in women's reproductive health HC Geisler, HC Safford, MJ Mitchell Small, 2300852, 2023 | 4 | 2023 |
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ... Theranostics 14 (1), 1, 2024 | 3 | 2024 |
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering AJ Mukalel, AG Hamilton, MM Billingsley, J Li, AS Thatte, X Han, ... Advanced Functional Materials, 2312038, 2024 | 1 | 2024 |
DDEL-04. ENGINEERED NANOCARRIERS TO ENHANCE DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER JP Straehla, C Hajal, H Safford, G Offeddu, J Wyckoff, RD Kamm, ... Neuro-Oncology 22 (Suppl 3), iii284, 2020 | 1 | 2020 |
Chromogenic beta-lactamase substrate A Shukla, D Alkekhia, S Shukla, H Safford US Patent 11,957,690, 2024 | | 2024 |
DDEL-17. POOLED CANCER CELL SCREENING IDENTIFIES GENOMIC DETERMINANTS OF NANOPARTICLE DELIVERY TO CANCER CELLS: SUB ANALYSIS OF CENTRAL NERVOUS SYSTEM TUMOR CELL LINES J Straehla, N Boehnke, H Safford, M Kocak, M Rees, M Ronan, ... Neuro-Oncology 24 (Supplement_7), vii97-vii97, 2022 | | 2022 |
Identification of a predictive biomarker for liposomal nanoparticle delivery through pan-cancer pooled screening JP Straehla, N Boehnke, H Safford, M Kocak, MG Rees, M Ronan, ... Cancer Research 82 (12_Supplement), 293-293, 2022 | | 2022 |
A PREDICTIVE MICROFLUIDIC MODEL OF VASCULARIZED GLIOMA TUMORS TO ASSESS TRAFFICKING OF THERAPEUTICS ACROSS THE BLOOD-BRAIN BARRIER C Hajal, J Straehla, G Offeddu, H Safford, P Hammond, R Kamm NEURO-ONCOLOGY 23, 217-218, 2021 | | 2021 |
LAYER-BY-LAYER NANOPARTICLES DESIGNED FOR DUAL BLOOD-BRAIN BARRIER AND GLIOMA TARGETING J Straehla, C Hajal, H Safford, G Offeddu, J Wyckoff, R Kamm, ... NEURO-ONCOLOGY 23, 168-169, 2021 | | 2021 |
Development of a multi-omic, pooled cancer cell screen for nanoparticle delivery JP Straehla, N Boehnke, M Kocak, M Ronan, H Safford, MG Rees, ... Cancer Research 81 (13_Supplement), 309-309, 2021 | | 2021 |