Implications of receptor-mediated endocytosis and intracellular trafficking dynamics in the development of antibody drug conjugates M Ritchie, L Tchistiakova, N Scott MAbs 5 (1), 13-21, 2013 | 279 | 2013 |
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis BJ Hawkins, KM Irrinki, K Mallilankaraman, YC Lien, Y Wang, ... Journal of cell biology 190 (3), 391-405, 2010 | 258 | 2010 |
STIM protein coupling in the activation of Orai channels Y Wang, X Deng, Y Zhou, E Hendron, S Mancarella, MF Ritchie, XD Tang, ... Proceedings of the National Academy of Sciences 106 (18), 7391-7396, 2009 | 162 | 2009 |
The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels Y Zhou, S Mancarella, Y Wang, C Yue, M Ritchie, DL Gill, J Soboloff Journal of biological chemistry 284 (29), 19164-19168, 2009 | 145 | 2009 |
STIM1 is required for attenuation of PMCA‐mediated Ca2+ clearance during T‐cell activation MF Ritchie, E Samakai, J Soboloff The EMBO journal 31 (5), 1123-1133, 2012 | 114 | 2012 |
The next generation of antibody drug conjugates F Mack, M Ritchie, P Sapra Seminars in oncology 41 (5), 637-652, 2014 | 85 | 2014 |
Wilms tumor suppressor 1 (WT1) and early growth response 1 (EGR1) are regulators of STIM1 expression MF Ritchie, C Yue, Y Zhou, PJ Houghton, J Soboloff Journal of biological chemistry 285 (14), 10591-10596, 2010 | 64 | 2010 |
Location and function of STIM1 in the activation of Ca2+ entry signals T Hewavitharana, X Deng, Y Wang, MF Ritchie, GV Girish, J Soboloff, ... Journal of biological chemistry 283 (38), 26252-26262, 2008 | 63 | 2008 |
Transcriptional mechanisms regulating Ca2+ homeostasis MF Ritchie, Y Zhou, J Soboloff Cell calcium 49 (5), 314-321, 2011 | 44 | 2011 |
WT1/EGR1-mediated control of STIM1 expression and function in cancer cells MF Ritchie, Y Zhou, J Soboloff Frontiers in bioscience: a journal and virtual library 16, 2402, 2011 | 40 | 2011 |
Development and applications of patient‐derived xenograft models in humanized mice for oncology and immune‐oncology drug discovery B Verma, M Ritchie, M Mancini Current Protocols in Pharmacology 78 (1), 14.41. 1-14.41. 12, 2017 | 11 | 2017 |
Selecting an optimal antibody for antibody-drug conjugate therapy M Ritchie, L Bloom, G Carven, P Sapra Antibody-drug conjugates: the 21st century magic bullets for Cancer, 23-48, 2015 | 7 | 2015 |
Pharmaco-Pheno-Multiomic integration reveals biomarker profiles and therapeutic response prediction models in leukemia and ovarian cancer G Silberberg, B Walling, A Wesa, A Audia, I Sloma, Y Zeng, G Han, J Tang, ... bioRxiv, 2022.06. 14.495846, 2022 | 2 | 2022 |
A novel gene signature predicting fibroblast composition in the TME allows for an improved selection of patient-derived xenograft (PDX) models for preclinical studies M Gilardi, G Silberberg, HW Tsai, S Cairo, C Killick-Cole, M Ritchie Cancer Research 84 (6_Supplement), 2941-2941, 2024 | | 2024 |
Raptamer-drug conjugates as molecularly targeted cancer therapeutics SP Vega, NE Ward, U Saini, L Castan-Chibas, G Kaushik, D Ciznadija, ... Cancer Research 84 (6_Supplement), 3210-3210, 2024 | | 2024 |
Mutational signatures in PDXs for improved understanding of drug response and companion biomarkers identification H Khoury, S Cairo, M Gilardi, M Ritchie, G Silberberg Cancer Research 84 (6_Supplement), 7115-7115, 2024 | | 2024 |
MADVAR: An algorithm that improves the relevance of computational biology output, while reducing compute time and space requirements G Silberberg, M Ritchie Cancer Research 84 (6_Supplement), 2327-2327, 2024 | | 2024 |
Deep Immunophenotyping Using High Complexity Flow Cytometry in Acute Myeloid Leukemia J Pearl, E Bruni, H Hsu, B Walling, P Schiavini, M Ritchie, M Mancini Blood 142 (Supplement 1), 6002-6002, 2023 | | 2023 |
Correlation Revealed between Gemtuzumab-Ozogamicin Efficacy and CD33+ Expression in AML Primary Samples through a Novel AML in Vitro Model M Gilardi, G Kaushik, B Walling, V Sambandam, P Schiavini, S Cairo, ... Blood 142, 7151, 2023 | | 2023 |
1286 A novel gene signature predicts immune infiltration phenotypes in humanized patient derived xenograft models M Gilardi, G Silberberg, HW Tsai, S Cairo, C Baer, K Cruz, KA Heidemann, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |