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Joseph A Marsh
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Sensitivity of secondary structure propensities to sequence differences between α‐and γ‐synuclein: implications for fibrillation
JA Marsh, VK Singh, Z Jia, JD Forman‐Kay
Protein Science 15 (12), 2795-2804, 2006
7762006
Structure, dynamics, assembly, and evolution of protein complexes
JA Marsh, SA Teichmann
Annual review of biochemistry 84, 551-575, 2015
4312015
Sequence determinants of compaction in intrinsically disordered proteins
JA Marsh, JD Forman-Kay
Biophysical journal 98 (10), 2383-2390, 2010
3962010
Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase
T Mittag, J Marsh, A Grishaev, S Orlicky, H Lin, F Sicheri, M Tyers, ...
Structure 18 (4), 494-506, 2010
2842010
Kinetic analysis of protein stability reveals age-dependent degradation
E McShane, C Sin, H Zauber, JN Wells, N Donnelly, X Wang, J Hou, ...
Cell 167 (3), 803-815. e21, 2016
2742016
Protein complexes are under evolutionary selection to assemble via ordered pathways
JA Marsh, H Hernandez, Z Hall, SE Ahnert, T Perica, CV Robinson, ...
Cell 153 (2), 461-470, 2013
2512013
Principles of assembly reveal a periodic table of protein complexes
SE Ahnert, JA Marsh, H Hernández, CV Robinson, SA Teichmann
Science 350 (6266), aaa2245, 2015
2342015
Relative solvent accessible surface area predicts protein conformational changes upon binding
JA Marsh, SA Teichmann
Structure 19 (6), 859-867, 2011
2112011
Structure and disorder in an unfolded state under nondenaturing conditions from ensemble models consistent with a large number of experimental restraints
JA Marsh, JD Forman-Kay
Journal of molecular biology 391 (2), 359-374, 2009
1852009
SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome
ND Shaw, H Brand, ZA Kupchinsky, H Bengani, L Plummer, TI Jones, ...
Nature genetics 49 (2), 238-248, 2017
1662017
Characterization of disordered proteins with ENSEMBLE
M Krzeminski, JA Marsh, C Neale, WY Choy, JD Forman-Kay
Bioinformatics 29 (3), 398-399, 2013
1562013
Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling
A Lepelley, MJ Martin-Niclós, M Le Bihan, JA Marsh, C Uggenti, GI Rice, ...
Journal of Experimental Medicine 217 (11), e20200600, 2020
1462020
Improved structural characterizations of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure
JA Marsh, C Neale, FE Jack, WY Choy, AY Lee, KA Crowhurst, ...
Journal of molecular biology 367 (5), 1494-1510, 2007
1392007
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions
P Heyn, CV Logan, A Fluteau, RC Challis, T Auchynnikava, CA Martin, ...
Nature genetics 51 (1), 96-105, 2019
1352019
Using deep mutational scanning to benchmark variant effect predictors and identify disease mutations
BJ Livesey, JA Marsh
Molecular systems biology 16 (7), e9380, 2020
1322020
Interrogation of mammalian protein complex structure, function, and membership using genome-scale fitness screens
J Pan, RM Meyers, BC Michel, N Mashtalir, AE Sizemore, JN Wells, ...
Cell systems 6 (5), 555-568. e7, 2018
1322018
Ensemble modeling of protein disordered states: experimental restraint contributions and validation
JA Marsh, JD Forman‐Kay
Proteins: Structure, Function, and Bioinformatics 80 (2), 556-572, 2012
1312012
Evolution of condensin and cohesin complexes driven by replacement of Kite by Hawk proteins
JN Wells, TG Gligoris, KA Nasmyth, JA Marsh
Current Biology 27 (1), R17-R18, 2017
1272017
Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators
JA Marsh, B Dancheck, MJ Ragusa, M Allaire, JD Forman-Kay, W Peti
Structure 18 (9), 1094-1103, 2010
1222010
Alpha helices are more robust to mutations than beta strands
G Abrusán, JA Marsh
PLoS computational biology 12 (12), e1005242, 2016
1162016
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Artiklar 1–20