Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration H Yang, P Tyagi, RS Kadam, CA Holden, UB Kompella ACS nano 6 (9), 7595-7606, 2012 | 207 | 2012 |
Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs CA Holden, P Tyagi, A Thakur, R Kadam, G Jadhav, UB Kompella, ... Nanomedicine: nanotechnology, biology and medicine 8 (5), 776-783, 2012 | 162 | 2012 |
Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells GC Baltazar, S Guha, W Lu, J Lim, K Boesze-Battaglia, AM Laties, P Tyagi, ... PloS one 7 (12), e49635, 2012 | 141 | 2012 |
Oral peptide delivery: Translational challenges due to physiological effects P Tyagi, S Pechenov, JA Subramony Journal of controlled release 287, 167-176, 2018 | 109 | 2018 |
Light-activated, in situ forming gel for sustained suprachoroidal delivery of bevacizumab P Tyagi, M Barros, JW Stansbury, UB Kompella Molecular pharmaceutics 10 (8), 2858-2867, 2013 | 99 | 2013 |
Targeted Intraceptor Nanoparticle Therapy reduces Angiogenesis and Fibrosis in Primate & Murine Macular Degeneration. L Luo, X Zhang, Y Hirano, P Tyagi, P Barabás, H Uehara, TR Miya, ... ACS nano, 2013 | 95 | 2013 |
Comparison of suprachoroidal drug delivery with subconjunctival and intravitreal routes using noninvasive fluorophotometry P Tyagi, RS Kadam, UB Kompella PloS one 7 (10), e48188, 2012 | 70 | 2012 |
Nanotherapeutics in oral and parenteral drug delivery: Key learnings and future outlooks as we think small P Tyagi, JA Subramony Journal of controlled release 272, 159-168, 2018 | 69 | 2018 |
Intravitreal poly(l-lactide) microparticles sustain retinal and choroidal delivery of TG-0054, a hydrophilic drug intended for neovascular diseases NB Shelke, R Kadam, P Tyagi, VR Rao, UB Kompella Drug delivery and translational research 1, 76-90, 2011 | 66 | 2011 |
Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor J Jin, KK Zhou, K Park, Y Hu, X Xu, Z Zheng, P Tyagi, UB Kompella, J Ma Investigative ophthalmology & visual science 52 (9), 6230-6237, 2011 | 64 | 2011 |
Supercritical fluid technology based large porous celecoxib–PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks … DS Dhanda, P Tyagi, SS Mirvish, UB Kompella Journal of controlled release 168 (3), 239-250, 2013 | 56 | 2013 |
Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries N Tewari-Singh, AK Jain, S Inturi, DA Ammar, C Agarwal, P Tyagi, ... Toxicology and applied pharmacology 264 (1), 23-31, 2012 | 55 | 2012 |
RETRACTED: Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide RS Kadam, P Tyagi, HF Edelhauser, UB Kompella International journal of pharmaceutics 434 (1-2), 140-147, 2012 | 51 | 2012 |
Suprachoroidal delivery in a rabbit ex vivo eye model: influence of drug properties, regional differences in delivery, and comparison with intravitreal and intracameral routes RS Kadam, J Williams, P Tyagi, HF Edelhauser, UB Kompella Molecular vision 19, 1198, 2013 | 49 | 2013 |
Biopolymer‐based carriers for DNA vaccine design CO Franck, L Fanslau, A Bistrovic Popov, P Tyagi, L Fruk Angewandte Chemie International Edition 60 (24), 13225-13243, 2021 | 44 | 2021 |
Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone YK Cho, H Uehara, JR Young, P Tyagi, UB Kompella, X Zhang, L Luo, ... Investigative ophthalmology & visual science 53 (4), 2328-2336, 2012 | 44 | 2012 |
Macromolecule nanotherapeutics: approaches and challenges P Tyagi, JL Santos Drug Discovery Today 23 (5), 1053-1061, 2018 | 38 | 2018 |
Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization Z Wang, R Cheng, K Lee, P Tyagi, L Ding, UB Kompella, J Chen, X Xu, ... Arteriosclerosis, thrombosis, and vascular biology 35 (4), 855-864, 2015 | 36 | 2015 |
Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease S Pechenov, J Revell, S Will, J Naylor, P Tyagi, C Patel, L Liang, L Tseng, ... Scientific reports 11 (1), 22521, 2021 | 33 | 2021 |
Dendrimer hydrogels H Yang, PN Desai, CA Holden, UB Kompella, P Tyagi US Patent App. 13/022,974, 2011 | 33 | 2011 |