|PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression|
CL Day, DE Kaufmann, P Kiepiela, JA Brown, ES Moodley, S Reddy, ...
Nature 443 (7109), 350-354, 2006
|AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study|
B Ledergerber, M Egger, V Erard, R Weber, B Hirschel, H Furrer, ...
Jama 282 (23), 2220-2226, 1999
|Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy|
F Pereyra, MM Addo, DE Kaufmann, Y Liu, T Miura, A Rathod, B Baker, ...
The Journal of infectious diseases 197 (4), 563-571, 2008
|Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction|
DE Kaufmann, DG Kavanagh, F Pereyra, JJ Zaunders, EW Mackey, ...
Nature immunology 8 (11), 1246-1254, 2007
|Loss of HIV-1–specific CD8+ T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4+ T Cells|
M Lichterfeld, DE Kaufmann, XG Yu, SK Mui, MM Addo, MN Johnston, ...
The Journal of experimental medicine 200 (6), 701-712, 2004
|Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF|
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
|CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART).|
D Kaufmann, G Pantaleo
The Lancet 351 (9104), 723-724, 1998
|A blueprint for HIV vaccine discovery|
DR Burton, R Ahmed, DH Barouch, ST Butera, S Crotty, A Godzik, ...
Cell host & microbe 12 (4), 396-407, 2012
|Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 …|
TM Allen, M Altfeld, SC Geer, ET Kalife, C Moore, KM O'Sullivan, ...
Journal of virology 79 (21), 13239-13249, 2005
|IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells|
MA Brockman, DS Kwon, DP Tighe, DF Pavlik, PC Rosato, J Sela, ...
Blood 114 (2), 346-356, 2009
|PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention|
DE Kaufmann, BD Walker
The Journal of Immunology 182 (10), 5891-5897, 2009
|Limited durability of viral control following treated acute HIV infection|
DE Kaufmann, M Lichterfeld, M Altfeld, MM Addo, MN Johnston, PK Lee, ...
PLoS Med 1 (2), e36, 2004
|TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection|
H Chen, ZM Ndhlovu, D Liu, LC Porter, JW Fang, S Darko, MA Brockman, ...
Nature immunology 13 (7), 691, 2012
|Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides|
DE Kaufmann, PM Bailey, J Sidney, B Wagner, PJ Norris, MN Johnston, ...
Journal of virology 78 (9), 4463-4477, 2004
|Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity|
M Veillette, A Désormeaux, H Medjahed, NE Gharsallah, M Coutu, ...
Journal of virology 88 (5), 2633-2644, 2014
|CXCL13 is a plasma biomarker of germinal center activity|
C Havenar-Daughton, M Lindqvist, A Heit, JE Wu, SM Reiss, K Kendric, ...
Proceedings of the National Academy of Sciences 113 (10), 2702-2707, 2016
|Responsiveness of HIV-specific CD4 T cells to PD-1 blockade|
F Porichis, DS Kwon, J Zupkosky, DP Tighe, A McMullen, MA Brockman, ...
Blood, The Journal of the American Society of Hematology 118 (4), 965-974, 2011
|High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control|
CT Berger, N Frahm, DA Price, B Mothe, M Ghebremichael, KL Hartman, ...
Journal of virology 85 (18), 9334-9345, 2011
|Impaired replication capacity of acute/early viruses in persons who become HIV controllers|
T Miura, ZL Brumme, MA Brockman, P Rosato, J Sela, CJ Brumme, ...
Journal of virology 84 (15), 7581-7591, 2010
|The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals|
M Veillette, M Coutu, J Richard, LA Batraville, O Dagher, N Bernard, ...
Journal of virology 89 (1), 545-551, 2015