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Luke E. Formosa
Luke E. Formosa
Group Leader, Department of Biochemistry and Molecular Biology, Monash Univerisity
Verifierad e-postadress på monash.edu
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Accessory subunits are integral for assembly and function of human mitochondrial complex I
DA Stroud, EE Surgenor, LE Formosa, B Reljic, AE Frazier, MG Dibley, ...
Nature 538 (7623), 123-126, 2016
4992016
Building a complex complex: Assembly of mitochondrial respiratory chain complex I
LE Formosa, MG Dibley, DA Stroud, MT Ryan
Seminars in cell & developmental biology 76, 154-162, 2018
1812018
Gene knockout using transcription activator-like effector nucleases (TALENs) reveals that human NDUFA9 protein is essential for stabilizing the junction between membrane and …
DA Stroud, LE Formosa, XW Wijeyeratne, TN Nguyen, MT Ryan
Journal of Biological Chemistry 288 (3), 1685-1690, 2013
972013
Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high‐intensity exercise training
VL Wyckelsma, I Levinger, MJ McKenna, LE Formosa, MT Ryan, ...
The Journal of physiology 595 (11), 3345-3359, 2017
862017
Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I
LE Formosa, M Mimaki, AE Frazier, M McKenzie, TL Stait, DR Thorburn, ...
Human molecular genetics 24 (10), 2952-2965, 2015
772015
The ‘mitochondrial contact site and cristae organising system’(MICOS) in health and human disease
MJ Eramo, V Lisnyak, LE Formosa, MT Ryan
The Journal of Biochemistry 167 (3), 243-255, 2020
762020
Biallelic mutations in TMEM126B cause severe complex I deficiency with a variable clinical phenotype
CL Alston, AG Compton, LE Formosa, V Strecker, M Oláhová, TB Haack, ...
The American Journal of Human Genetics 99 (1), 217-227, 2016
712016
Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
LE Formosa, L Muellner-Wong, B Reljic, AJ Sharpe, TD Jackson, ...
Cell Reports 31 (3), 107541, 2020
702020
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect
K Thompson, N Mai, M Oláhová, F Scialó, LE Formosa, DA Stroud, ...
EMBO Molecular Medicine 10 (11), e9060, 2018
692018
Mitochondrial OXPHOS complex assembly lines
LE Formosa, MT Ryan
Nature cell biology 20 (5), 511-513, 2018
612018
Fatal perinatal mitochondrial cardiac failure caused by recurrent de novo duplications in the ATAD3 locus
AE Frazier, AG Compton, Y Kishita, DH Hock, AME Welch, ...
Med 2 (1), 49-73. e10, 2021
512021
The mitochondrial acyl-carrier protein interaction network highlights important roles for LYRM family members in complex I and mitoribosome assembly
MG Dibley, LE Formosa, B Lyu, B Reljic, D McGann, L Muellner-Wong, ...
Molecular & Cellular Proteomics 19 (1), 65-77, 2020
432020
Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality
KM Quinn, T Hussain, F Kraus, LE Formosa, WK Lam, MJ Dagley, ...
Nature Communications 11 (1), 2857, 2020
372020
Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
E Fernandez-Vizarra, S Lopez-Calcerrada, A Sierra-Magro, ...
Cell Metabolism 34 (11), 1792-1808. e6, 2022
292022
Mitochondrial fusion: Reaching the end of mitofusin’s tether
LE Formosa, MT Ryan
The Journal of Cell Biology 215 (5), 597, 2016
292016
Optic atrophy–associated TMEM126A is an assembly factor for the ND4-module of mitochondrial complex I
LE Formosa, B Reljic, AJ Sharpe, DH Hock, L Muellner-Wong, DA Stroud, ...
Proceedings of the National Academy of Sciences 118 (17), e2019665118, 2021
232021
A homozygous variant in NDUFA8 is associated with developmental delay, microcephaly, and epilepsy due to mitochondrial complex I deficiency
Y Yatsuka, Y Kishita, LE Formosa, M Shimura, F Nozaki, T Fujii, KR Nitta, ...
Clinical Genetics 98 (2), 155-165, 2020
192020
SILAC-based complexome profiling dissects the structural organization of the human respiratory supercomplexes in SCAFIKO cells
E Fernández-Vizarra, S López-Calcerrada, LE Formosa, R Pérez-Pérez, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1862 (7), 148414, 2021
172021
Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module
TD Jackson, JJ Crameri, L Muellner-Wong, AE Frazier, CS Palmer, ...
Proceedings of the National Academy of Sciences 119 (13), e2115566119, 2022
162022
Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly
LE Formosa, S Maghool, AJ Sharpe, B Reljic, L Muellner-Wong, ...
Proceedings of the National Academy of Sciences 119 (9), e2110357119, 2022
15*2022
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Artiklar 1–20