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Fernando Peláez
Fernando Peláez
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Platensimycin is a selective FabF inhibitor with potent antibiotic properties
J Wang, SM Soisson, K Young, W Shoop, S Kodali, A Galgoci, R Painter, ...
Nature 441 (7091), 358-361, 2006
10022006
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
B Zhang, G Salituro, D Szalkowski, Z Li, Y Zhang, I Royo, D Vilella, ...
Science 284 (5416), 974-977, 1999
6451999
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
J Wang, S Kodali, SH Lee, A Galgoci, R Painter, K Dorso, F Racine, ...
Proceedings of the National Academy of Sciences 104 (18), 7612-7616, 2007
4502007
Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain)
A Val, G Platas, A Basilio, A Cabello, J Gorrochategui, I Suay, F Vicente, ...
International Microbiology 4, 35-40, 2001
4502001
Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors
J Onishi, M Meinz, J Thompson, J Curotto, S Dreikorn, M Rosenbach, ...
Antimicrobial agents and chemotherapy 44 (2), 368-377, 2000
4162000
Screening of basidiomycetes for antimicrobial activities
I Suay, F Arenal, FJ Asensio, A Basilio, M Angeles Cabello, ...
Antonie van Leeuwenhoek 78, 129-140, 2000
3872000
The historical delivery of antibiotics from microbial natural products—can history repeat?
F Pelaez
Biochemical pharmacology 71 (7), 981-990, 2006
3552006
Primary structure and inhibition of protein synthesis in eukaryotic cell‐free system of a novel thionin, γ‐hordothionin, from barley endosperm
E Mendez, A Moreno, F Colilla, F Pelaez, GG Limas, R Mendez, F Soriano, ...
European journal of biochemistry 194 (2), 533-539, 1990
3171990
Farnesoid X receptor activates transcription of the phospholipid pump MDR3
L Huang, A Zhao, JL Lew, T Zhang, Y Hrywna, JR Thompson, N de Pedro, ...
Journal of Biological Chemistry 278 (51), 51085-51090, 2003
2992003
Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy
SB Singh, H Jayasuriya, JG Ondeyka, KB Herath, C Zhang, DL Zink, ...
Journal of the American Chemical Society 128 (36), 11916-11920, 2006
2972006
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump
J Cui, LI Huang, A Zhao, JL Lew, J Yu, S Sahoo, PT Meinke, I Royo, ...
Journal of Biological Chemistry 278 (12), 10214-10220, 2003
2802003
Microbial natural products as a source of antifungals
MF Vicente, A Basilio, A Cabello, F Peláez
Clinical microbiology and infection 9 (1), 15-32, 2003
2782003
Discovery of FabH/FabF inhibitors from natural products
K Young, H Jayasuriya, JG Ondeyka, K Herath, C Zhang, S Kodali, ...
Antimicrobial agents and chemotherapy 50 (2), 519-526, 2006
2562006
The farnesoid X receptor controls gene expression in a ligand-and promoter-selective fashion
JL Lew, A Zhao, J Yu, L Huang, N De Pedro, F Peláez, SD Wright, J Cui
Journal of Biological Chemistry 279 (10), 8856-8861, 2004
2522004
Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad‐spectrum antibiotic activity
H Jayasuriya, KB Herath, C Zhang, DL Zink, A Basilio, O Genilloud, ...
Angewandte Chemie International Edition 46 (25), 4684-4688, 2007
2452007
Geographical and seasonal influences on the distribution of fungal endophytes in Quercus ilex
J Collado, G Platas, I González, F Peláez
The New Phytologist 144 (3), 525-532, 1999
2371999
The discovery of enfumafungin, a novel antifungal compound produced by an endophytic Hormonema species biological activity and taxonomy of the producing organisms
F Peláez, A Cabello, G Platas, MT Díez, AG del Val, A Basilio, I Martán, ...
Systematic and applied microbiology 23 (3), 333-343, 2000
1932000
The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis producing organism, fermentation, isolation, and biological activity
SM Mandala, RA Thornton, BR Frommer, JE Curotto, W Rozdilsky, ...
The Journal of antibiotics 48 (5), 349-356, 1995
1891995
Endophytic fungi from plants living on gypsum soils as a source of secondary metabolites with antimicrobial activity
F Peláez, J Collado, F Arenal, A Basilio, A Cabello, MTD Matas, JB Garcia, ...
Mycological Research 102 (6), 755-761, 1998
1781998
Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays
GF Bills, G Platas, A Fillola, MR Jiménez, J Collado, F Vicente, J Martín, ...
Journal of applied microbiology 104 (6), 1644-1658, 2008
1672008
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Artiklar 1–20