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Mahak Singhal
Mahak Singhal
European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University
Verified email at medma.uni-heidelberg.de
Title
Cited by
Cited by
Year
Preclinical mouse solid tumour models: status quo, challenges and perspectives
N Gengenbacher, M Singhal, HG Augustin
Nature Reviews Cancer 17 (12), 751-765, 2017
3022017
Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence
MR Garcia, B Steinbauer, K Srivastava, M Singhal, F Mattijssen, A Maida, ...
Cell metabolism 26 (6), 842-855. e5, 2017
2202017
Endothelial Tie1–mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis
S La Porta, L Roth, M Singhal, C Mogler, C Spegg, B Schieb, X Qu, ...
The Journal of clinical investigation 128 (2), 834-845, 2018
922018
Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis
S Jagadeeshan, YR Krishnamoorthy, M Singhal, A Subramanian, ...
Oncogene 34 (4), 455-464, 2015
602015
STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis
Y Shen, X Wang, Y Liu, M Singhal, C Gürkaşlar, AF Valls, Y Lei, W Hu, ...
Science Signaling 14 (712), eabj8393, 2021
592021
P21-activated kinase 1 (Pak1) signaling influences therapeutic outcome in pancreatic cancer
S Jagadeeshan, A Subramanian, S Tentu, S Beesetti, M Singhal, ...
Annals of oncology 27 (8), 1546-1556, 2016
452016
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis
M Singhal, N Gengenbacher, AA Abdul Pari, M Kamiyama, L Hai, ...
Science translational medicine 13 (609), eabe6805, 2021
412021
Endothelial cell fitness dictates the source of regenerating liver vasculature
M Singhal, X Liu, D Inverso, K Jiang, J Dai, H He, S Bartels, W Li, ...
Journal of Experimental Medicine 215 (10), 2497-2508, 2018
322018
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
MN O’Connor, DM Kallenberg, C Camilli, C Pilotti, A Dritsoula, ...
Med 2 (11), 1231-1252. e10, 2021
302021
Beyond angiogenesis: exploiting angiocrine factors to restrict tumor progression and metastasis
M Singhal, HG Augustin
Cancer research 80 (4), 659-662, 2020
302020
Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma
AA Abdul Pari, M Singhal, C Huebers, C Mogler, B Schieb, A Gampp, ...
Cancer research 80 (12), 2586-2598, 2020
282020
Timed Ang2-targeted therapy identifies the angiopoietin–tie pathway as key regulator of fatal lymphogenous metastasis
N Gengenbacher, M Singhal, C Mogler, L Hai, L Milde, AAA Pari, ...
Cancer discovery 11 (2), 424-445, 2021
232021
Emerging paradigms in metastasis research
AA Abdul Pari, M Singhal, HG Augustin
Journal of Experimental Medicine 218 (1), e20190218, 2020
232020
Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody
M Singhal, N Gengenbacher, S La Porta, S Gehrs, J Shi, M Kamiyama, ...
EMBO Molecular Medicine 12 (6), e11164, 2020
172020
Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
MA Karreman, AT Bauer, G Solecki, AS Berghoff, CD Mayer, K Frey, ...
Cancer research 83 (8), 1299-1314, 2023
152023
Primary tumor–derived systemic nANGPTL4 inhibits metastasis
C Hübers, AA Abdul Pari, D Grieshober, M Petkov, A Schmidt, T Messmer, ...
Journal of Experimental Medicine 220 (1), e20202595, 2022
152022
Threonine 209 phosphorylation on RUNX3 by Pak1 is a molecular switch for its dualistic functions
A Kumar, M Singhal, C Chopra, S Srinivasan, RP Surabhi, R Kanumuri, ...
Oncogene 35 (37), 4857-4865, 2016
152016
Molecular mechanism of regulation of MTA1 expression by granulocyte colony-stimulating factor
AS Kumar, S Jagadeeshan, A Subramanian, SB Chidambaram, ...
Journal of Biological Chemistry 291 (23), 12310-12321, 2016
112016
Caspase‐8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
N Tisch, C Mogler, A Stojanovic, R Luck, EA Korhonen, A Ellerkmann, ...
EMBO Molecular Medicine 14 (6), e14121, 2022
102022
Activating NO–sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury
H He, W Yang, N Su, C Zhang, J Dai, F Han, M Singhal, W Bai, X Zhu, ...
Journal of Experimental Medicine 220 (2), e20211422, 2022
52022
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