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George L. Hamilton
George L. Hamilton
Clemson University Graduate Researcher
Verified email at g.clemson.edu
Title
Cited by
Cited by
Year
Identifying weak interdomain interactions that stabilize the supertertiary structure of the N-terminal tandem PDZ domains of PSD-95
IS Yanez Orozco, FA Mindlin, J Ma, B Wang, B Levesque, M Spencer, ...
Nature communications 9 (1), 3724, 2018
552018
Specific conformational dynamics and expansion underpin a multi-step mechanism for specific binding of p27 with Cdk2/Cyclin A
M Tsytlonok, K Hemmen, G Hamilton, N Kolimi, S Felekyan, CAM Seidel, ...
Journal of molecular biology 432 (9), 2998-3017, 2020
312020
A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories
M Götz, A Barth, SSR Bohr, R Börner, J Chen, T Cordes, DA Erie, ...
Nature communications 13 (1), 5402, 2022
282022
Ensemble switching unveils a kinetic rheostat mechanism of the eukaryotic thiamine pyrophosphate riboswitch
J Ma, N Saikia, S Godar, GL Hamilton, F Ding, J Alper, H Sanabria
RNA 27 (7), 771-790, 2021
192021
Fuzzy supertertiary interactions within PSD-95 enable ligand binding
GL Hamilton, N Saikia, S Basak, FS Welcome, F Wu, J Kubiak, C Zhang, ...
Elife 11, e77242, 2022
172022
Multiparameter fluorescence spectroscopy of single molecules
G Hamilton, H Sanabria
Spectroscopy and dynamics of single molecules, 269-333, 2019
162019
Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25
N Saikia, IS Yanez-Orozco, R Qiu, P Hao, S Milikisiyants, E Ou, ...
Cell Reports Physical Science 2 (11), 2021
142021
Intrinsically disordered regions of the DNA-binding domain of human FoxP1 facilitate domain swapping
E Medina, P Villalobos, GL Hamilton, EA Komives, H Sanabria, ...
Journal of molecular biology 432 (19), 5411-5429, 2020
142020
Spectroscopy and Dynamics of Single Molecules
G Hamilton, H Sanabria, CK Johnson
Elsevier, 2019
82019
Coevolution and smFRET Enhances Conformation Sampling and FRET Experimental Design in Tandem PDZ1–2 Proteins
A Krishnamohan, GL Hamilton, R Goutam, H Sanabria, F Morcos
The Journal of Physical Chemistry B 127 (4), 884-898, 2023
42023
Inferring kinetic rate constants from single-molecule FRET trajectories–a blind benchmark of kinetic analysis tools
M Götz, A Barth, SSR Bohr, R Börner, J Chen, T Cordes, DA Erie, ...
bioRxiv, 2021.11. 23.469671, 2021
32021
Reporting on the future of integrative structural biology ORAU workshop
GL Hamilton, J Alper, H Sanabria
Frontiers in bioscience (Landmark edition) 25, 43, 2020
22020
DNA facilitates heterodimerization between human transcription factors FoxP1 and FoxP2 by increasing their conformational flexibility
R Coñuecar, I Asela, M Rivera, P Galaz-Davison, J González-Higueras, ...
Iscience 26 (7), 2023
12023
Enhancing protein dynamics studies with an automated FRET network design informed by direct coupling analysis
A Krishnamohan, GL Hamilton, FX Duffy, F Morcos, H Sanabria
Biophysical Journal 123 (3), 462a, 2024
2024
Inter-domain linkers modulate supertertiary structural dynamics in the N-terminal PDZ tandem of PSD-95
GL Hamilton, N Saikia, B Levesque, RK Goutam, C Zhang, H Sanabria, ...
Biophysical Journal 121 (3), 41a-42a, 2022
2022
Fuzzy Supertertiary Interactions within PSD-95 Enable Ligand Binding
F Wu, F Ding, CAM Seidel, S Basak, FS Welcome, ME Bowen, N Saikia, ...
Zenodo, 2022
2022
Sequence and Structure Based Approach for Automated FRET Network Design
GL Hamilton, H Sanabria, F Morcos, N Kolimi, A Krishnamohan
Biophysical Journal 120 (3), 188a, 2021
2021
Interdomain Dynamics Underlie Function and Regulation of Postsynaptic Density Protein 95
GL Hamilton, N Saikia, J Park, J Kubiak, CA Seidel, ME Bowen, F Ding, ...
Biophysical Journal 118 (3), 336a, 2020
2020
Expansion Upon Binding Guides p27 Binding to Cdk2/cyclinA
M Tsytlonok, K Hemmen, GL Hamilton, N Kolimi, S Felekyan, CA Seidel, ...
Biophysical Journal 118 (3), 371a, 2020
2020
Dynamic Organization in the Supertertiary Structure of PDZ3-SH3-GuK Core Supramodule of PSD-95 Scaffold Protein
N Saikia, GL Hamilton, H Sanabria, ME Bowen, F Ding
Biophysical Journal 118 (3), 206a, 2020
2020
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