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Michael Gundry
Michael Gundry
Boston Children's Hospital
Verifierad e-postadress på childrens.harvard.edu
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Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9
MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ...
Cell reports 17 (5), 1453-1461, 2016
2772016
Mutant NPM1 maintains the leukemic state through HOX expression
L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ...
Cancer cell 34 (3), 499-512. e9, 2018
2392018
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ...
Genome biology 18, 1-11, 2017
2162017
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang, Y Zhou, W Li, ...
Nature communications 8 (1), 16026, 2017
2082017
DNMT3A in Leukemia
L Brunetti, MC Gundry, MA Goodell
Cold Spring Harbor perspectives in medicine 7 (2), a030320, 2017
1762017
Direct mutation analysis by high-throughput sequencing: from germline to low-abundant, somatic variants
M Gundry, J Vijg
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 729 (1 …, 2012
1142012
Direct, genome-wide assessment of DNA mutations in single cells
M Gundry, W Li, SB Maqbool, J Vijg
Nucleic acids research 40 (5), 2032-2040, 2012
862012
5-aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1
AY Maslov, M Lee, M Gundry, S Gravina, N Strogonova, C Tazearslan, ...
Oncogene 31 (50), 5172-5179, 2012
832012
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity
AE Pohodich, H Yalamanchili, AT Raman, YW Wan, M Gundry, S Hao, ...
Elife 7, e34031, 2018
482018
Highly efficient gene disruption of murine and human hematopoietic progenitor cells by CRISPR/Cas9
L Brunetti, MC Gundry, A Kitano, D Nakada, MA Goodell
JoVE (Journal of Visualized Experiments), e57278, 2018
392018
New insights into the biology of acute myeloid leukemia with mutated NPM1
L Brunetti, MC Gundry, MA Goodell
International Journal of Hematology 110, 150-160, 2019
362019
Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells
R Basar, M Daher, N Uprety, E Gokdemir, A Alsuliman, E Ensley, G Ozcan, ...
Blood advances 4 (14), 3357-3367, 2020
302020
Tissue-biased expansion of DNMT3A-mutant clones in a mosaic individual is associated with conserved epigenetic erosion
A Tovy, JM Reyes, MC Gundry, L Brunetti, H Lee-Six, M Petljak, HJ Park, ...
Cell Stem Cell 27 (2), 326-335. e4, 2020
262020
It’s all about MEis: menin-MLL inhibition eradicates NPM1-mutated and MLL-rearranged acute leukemias in mice
MC Gundry, MA Goodell, L Brunetti
Cancer Cell 37 (3), 267-269, 2020
252020
Technical considerations for the use of CRISPR/Cas9 in hematology research
MC Gundry, DP Dever, D Yudovich, DE Bauer, S Haas, AC Wilkinson, ...
Experimental hematology 54, 4-11, 2017
152017
Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage
Q Zhu, Y Niu, M Gundry, C Zong
Science Advances 7 (27), eabf3329, 2021
132021
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells
R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ...
Nature cell biology 25 (4), 528-539, 2023
102023
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities
JH Rogers, R Gupta, JM Reyes, MC Gundry, G Medrano, A Guzman, ...
Blood Advances 5 (19), 3876-3890, 2021
102021
Loss of de novo DNA methyltransferase DNMT3A impacts alternative splicing in hematopoietic stem cells
R Ramabadran, J Wang, A Guzman, SM Cullen, L Brunetti, M Gundry, ...
Blood 130, 1, 2017
72017
Two-pronged cell therapy for B-cell malignancies: engineering NK cells to target CD22 and redirect bystander T cells to CD19
MP Velasquez, A Szoor, CL Bonifant, A Vaidya, L Brunetti, MC Gundry, ...
Blood 128 (22), 4560, 2016
62016
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Artiklar 1–20